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New Study Finds Wide Evidence Of Mislabeling For CBD Products

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By Joana Scopel

In a new study, Johns Hopkins Medicine researchers tested more than a hundred topical cannabidiol (CBD) products, that are available online and at retail stores and found “significant evidence of inaccurate and misleading labeling of CBD content.”

In addition, some of these products claimed to be free of THC, the main active ingredient in cannabis that can cause a “high.” However, the study showed that some of these nonprescription products actually contained amounts of THC (delta-9 tetrahydrocannabinol).

CBD
Photo by Erin_Hinterland via Pixabay

RELATED: Report: CBD Content On Labels Differs From Levels Found In Actual Products

Moreover, researchers found that some CBD products made therapeutic claims not approved by the U.S. Food and Drug Administration (FDA).

“To date, the FDA has only approved one prescription CBD product to treat seizures associated with rare epilepsy disorders, and two prescription THC products for nausea and vomiting associated with chemotherapy and for loss of appetite and weight loss associated with HIV/AIDS,” reads the study published July 20 in JAMA Network Open, and supported by the Substance Abuse and Mental Health Services Administration (SAMHSA).

Tory Spindle, Ph.D., assistant professor of psychiatry and behavioral sciences at the Johns Hopkins University School of Medicine, and lead author of the study expressed that “misleading labels can result in people using poorly regulated and expensive CBD products instead of FDA-approved products that are established as safe and effective for a given health condition.”

“Recent research has shown that people who use CBD products containing even small amounts of THC could potentially test positive for cannabis using a conventional drug test,” Spindle added. However, that has not been determined yet for topical CBD products.

Study Results

Researchers purchased 105 CBD topical products, including lotions, creams, and patches, to begin the study. Those products were tested using a technology called “gas chromatography-mass spectrometry” to identify the actual amount of CBD and THC they contained.

“Only 89 (85%) of the 105 tested products listed the total amount of CBD in milligrams on the label. Of the 89 products, 16 (18%) contained less CBD than advertised, 52 (58%) contained more CBD than advertised, and 21 (24%) were accurately labeled,” stated the study.

Not All CBD Topicals Are Treated Equal
Photo by Sora Shimazaki from Pexels

RELATED: CBD Is Expensive: How The Industry Can Re-Think Its Pricing For Consumers

“On average, the in-store products contained 21% more CBD than advertised and the online products contained 10% more CBD than advertised, though CBD label accuracy varied widely across products.”

THC was detected in 37 (35%) of the 105 products, though all were within the legal limit of 0.3%. Four (11%) of those 37 were labeled as “THC free,” 14 (38%) stated they contained less than 0.3% THC and 19 (51%) did not reference THC on the label.

“Of the 105 products, 29 (28%) made a therapeutic claim, mostly about pain/inflammation, 15 (14%) made a cosmetic/beauty claim (e.g., that they alleviate wrinkles or nourish/improve skin) and 49 (47%) noted they were not FDA approved. The other 56 (53%) products made no reference to the FDA,” expressed the researchers.

“It’s important to note that the FDA has not approved CBD products to treat any of the conditions advertised on the products we tested,” added Spindle, who also is a faculty member at the Johns Hopkins Cannabis Science Laboratory.

Ryan Vandrey, Ph.D., professor of psychiatry and behavioral sciences at the Johns Hopkins University School of Medicine and the study’s senior author said that “the variability in the chemical content and labeling found in our study highlights the need for better regulatory oversight of CBD products to ensure consumer safety.”

The study’s authors understood that “such regulation would ensure CBD products meet established standards for quality assurance so consumers can make informed decisions about product selection and are not misled by unproven therapeutic or cosmetic claims.”

The researchers concluded the study by saying that people should consult with their doctor before starting any CBD regimen.

CBD
Photo by CRYSTALWEED cannabis via Unsplash

Is The Labeling Of Cannabis Products Assertive?

According to another study that examined almost 90,000 samples across six states, labels on cannabis products are not very useful since researchers found that “commercial labels do not consistently align with the observed chemical diversity,” of cannabis products.

Researchers asked for a labeling system similar to the FDA’s “nutrition fact panel” for food. “Our findings suggest that the prevailing labeling system is not an effective or safe way to provide information about these products,” said co-author Brian Keegan, an assistant professor of Information Science at CU Boulder. “This is a real challenge for an industry that is trying to professionalize itself.”

This article originally appeared on Benzinga and has been reposted with permission.



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Why Cannabis Dabbing Is An Emerging Trend

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Dr. Matthew Halpert – An inside look at Medterra CBD

John Malanca talks through good, bad, and exciting in cannabis medicine in this discussion of CBD with Dr. Halpert. When the Farm Bill expanded access to cannabidiol, manufacturers’ interest exploded. However, in order to make honest claims, Dr. Halpert teamed with Medterra CBD to determine the real healing powers of this remarkable cannabinoid.



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breast cancer

The Latest Cannabis Clinical Trials in 2022

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Nurse Mark’s Budding Interest

Tune in to watch John Malanca as he hosts this remarkable man.  Personable and joyous it is hard to believe Mark has struggled with mental illness and depression most of his life.  At a time when many of us would sit back and enjoy the fruits of our labor, Mark opened the books and became an RN, BSN and now will be among the first health care professionals to receive a master’s degree in Cannabis Therapeutics.



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5 Reasons to Celebrate National CBD Day  – Cannabis News, Lifestyle

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August 8 is National CBD Day! This day is to celebrate one of our favourite cannabinoids and spread awareness about its benefits. And here are five reasons to celebrate it!

CBD stands for Cannabidiol, the second most active ingredient in cannabis. CBD is also present in the hemp plant. Hemp and “marijuana” are technically the same plant genus. Hemp has no psychoactive properties that make users feel stoned or high. 

There are plenty of reasons to enjoy daily CBD supplementation. But here are our top five.

Reason #1: Anti-Anxiety

National CBD Day 

Research suggests CBD helps regulate serotonin, a transmitter associated with a sense of well-being. Many anti-anxiety pharmaceuticals target serotonin levels but with plenty of adverse side effects. The side effects of CBD are nil. 

While researchers speculate on why CBD works for anxiety, their clinical research demonstrates that it does indeed work. One study saw researchers use tomographic imaging to peer inside the brains of people with a social anxiety disorder (SAD), a placebo group, and a healthy control group.

Their findings confirmed that CBD significantly reduced anxiety in SAD patients. The study concludes: that CBD interacts with our cannabinoid receptors to inhibit social anxiety. 

Reason #2: CBDa Benefits

Cannabidiolic acid, known as CBDa, is the acidic precursor of CBD. If you’ve ever made edibles or concentrates, you will likely put your bud through a “decarb” process. This process removes the acidic form and makes the cannabinoid pharmacologically active.

All is well if you’re making THC-infused butter. But what about the benefits of CBDa?

CBDA doesn’t interact with our endocannabinoid system, nor does it bind to our cannabinoid receptors. So what’s the point? Researchers think CBDa may interact with COX-2, an enzyme associated with inflammation. 

“Since the COVID news came out, proving that CBDa helps prevent spike proteins from entering your body, the whole world is shifting toward CBDa,” says Inesa Ponomariovaite, cannabis expert and founder of Nesas Hemp. “This plant is meant to heal people, not to get you high or destroy your life.”

Reason #3: Neuroprotective Properties 

According to some research, CBD’s role in the endocannabinoid system may provide benefits for those with neurological disorders. CBD shows much promise in treating neurological conditions such as epilepsy and MS. 

One study essentially proved beyond a reasonable doubt that CBD significantly reduces seizure activity in children with Dravet syndrome. In fact, there’s only ever been one CBD product to receive approval from the Food & Drug Administration. Epidiolex is used to treat seizures associated with Lennox Gastaut syndrome, Dravet syndrome, or tuberous sclerosis complex.

Promising research also links CBD to improved quality of life in people with Parkinson’s disease.

Reason #4: Protect Yourself Against COVID on CBD Day

National CBD Day 

In March 2021, the National Institute of Health released a study that shocked the internet and went virtually ignored in the corporate press. To quote from the abstract: 

“CBD and its metabolite, 7-OH-CBD… potently block SARS-CoV-2 replication in lung epithelial cells. CBD acts after cellular infection, inhibiting viral gene expression and reversing many effects of SARS-CoV-2 on host gene transcription.”

In other words: “Cannabidiol from the cannabis plant has potential to prevent and inhibit SARS-CoV-2 infection.”

That’s right – a daily CBD supplementation can protect you against covid. And this isn’t the only study suggesting this.

Earlier this yearresearchers found that patients taking FDA-approved cannabidiol for their epilepsy had a lower rate of positive COVID tests than a nationwide sample.

And a third study found that CBDa and CBGa bind to the spike proteins of SARSCOV-2. These cannabinoids prevented the virus from entering cells and causing infection.

If this hasn’t convinced you to try cannabidiol, then what will?

Reason #5: Improve Heart Health

national CBD Day 

Growing evidence that the mRNA vaccines cause myocarditis in young males is too hard to ignore. Myocarditis weakens the heart, so the rest of the body doesn’t receive enough blood. Clots form in the heart, leading to a stroke or heart attack.

And as suspected, young people are dying at higher rates than any other demographic. The corporate press calls it a “mysterious syndrome,” called Sudden Adult Death Syndrome, which directly affects the heart.

CBD directly affects the heart but in a positive way. One small study showed it could lower high blood pressure. Researchers treated nine healthy men with CBD oil and a placebo, indicating that CBD did something the placebo could not.

The study also showed how CBD limited blood pressure increases when researchers put the subjects in stressful situations.

Another study looked at 26 healthy men, CBD and reductions in blood pressure and came to the same results. They also found that CBD improved blood flow through their arteries compared to the placebo group.

However, the researchers noted you lose CBD’s benefits after one week of cessation. So, like any medication or supplement, you must be consistent with it.

CBD Day for the Win!

These are just five reasons to try cannabidiol today. But there are plenty more, and we’ve barely scratched the surface here. 

Cannabidiol is a cannabinoid like the endogenous cannabinoids that make our brain and body function normally. When our natural cannabinoids are out of whack, or we feel we need that extra boost, supplementing with CBD helps.

CBD could be the solution you’re looking for. And scientific research backs up its beneficial claims. So what are you waiting for? August 8 is its national day! Is there any better day of the year to try CBD? 

Footnote(s)

https://pubmed.ncbi.nlm.nih.gov/24525548/
https://pubmed.ncbi.nlm.nih.gov/26724101/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161868/
https://www.ncbi.nlm.nih.gov/books/NBK539859/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470879/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256118/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7987002/
https://www.uchicagomedicine.org/forefront/research-and-discoveries-articles/researchers-recommend-clinical-trials-for-cbd
https://pubs.acs.org/doi/10.1021/acs.jnatprod.1c00946#
https://www.nature.com/articles/npp20116?foxtrotcallback=true
https://www.dailymail.co.uk/news/article-10895067/Doctors-trying-determine-young-people-suddenly-dying.html
https://www.medrxiv.org/content/10.1101/2021.12.02.21267156v1.full.pdf
https://www.medrxiv.org/content/10.1101/2021.08.30.21262866v1.full.pdf
https://pubmed.ncbi.nlm.nih.gov/34432976/
https://www.nature.com/articles/s41591-021-01630-0.pdf





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