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Rare & Strange Medical Disorders Crossword Puzzle – Cannabis News, Lifestyle

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The human body is super duper weird. It’s a complex, intricate puzzle of functions coming together and creating life. Sometimes, the most bizarre things can go wrong. For the unlucky people who live with rare medical disorders, life is harder in the strangest ways. The worst part is that physically, you know something is going on but most of the time, you don’t know why. It can be hard to pinpoint a rare and strange medical disorder because most people don’t know they exist…

Before going any further into this subject, let’s see what you know about rare medical disorders. Try the crossword below and be ready to think outside the box. It’s all about unusual medical conditions and if you don’t know an answer, you’ll find it below the puzzle. Expect to be surprised.

Foreign accent syndrome is a real and extremely rare condition caused by a brain injury or stroke. It’s a speech impediment that happens when there is damage to the language coordination center of the brain. Recorded accent changes have included Spanish to Hungarian, English to French, and Japanese to Korean.

Runny nose or not?

Honeymoon rhinitis is a condition that causes you to develop a stuffy nose every time you are aroused. There are small structures in our nose called turbinates, that cleanse and humidify the air we breathe. It just so happens that they contain erectile tissue. 

Here’s how it goes:

  • Sexual arousal triggers the sympathetic nervous system, causing vasoconstriction. 
  • Erectile tissue present within the nose swells, causing congestion.
  • There is less blood flow to the nose because it’s going to other places. So the congestion remains.
  • Post orgasm, blood flow returns to normal and the nasal congestion clears up.

Is my brain leaking?

A cerebral spinal fluid leak is a very serious condition that carries a high risk of meningitis. It’s very treatable and 85% of cases clear up by themselves in the first week. CSF leaks happen when the fluid surrounding your brain and spinal cord leak out of your nose. Usually caused by a traumatic injury or genetic factors, a small hole forms in the membrane containing this fluid. As a result, a clear thin fluid drips out of the nose and causes severe headaches at the back of the head. A CSF leak is different from a standard runny nose in two noticeable ways:

  1. If you wipe your nose with a tissue, the fluid will not stiffen.
  2. The runny nose will become noticeably worse during certain positions such as bending over to put on shoes.

Stomach 

Auto brewery syndrome is a condition that causes intoxication after eating carbohydrate-rich foods. Also known as gut fermentation syndrome, pure ethanol is produced in the person’s stomach due to an excess of yeast.

This one sucks…

Fish odor syndrome, also known as trimethylaminuria, causes a person’s sweat, breath, and urine to smell like rotting fish. It’s caused when the body is unable to break down the compound trimethylamine. As a result, it builds up in the body until it is excreted. Trimethylamine has been described as smelling like decaying fish, hot garbage, and rotten eggs; sadly, so do the people with this condition.

Thanks for playing this week’s crossword on strange medical conditions. Want more? Click here for last week’s Cannabis Concentrate Crossword Puzzle!

Footnote(s)

https://www.human.com.sg/stuffy-nose-while-having-sex#3
https://www.medicalnewstoday.com/articles/323395#Auto-brewery-syndrome
https://my.clevelandclinic.org/health/diseases/16854-cerebrospinal-fluid-csf-leak
https://www.nhs.uk/conditions/trimethylaminuria/#:~:text=Trimethylaminuria%20(TMAU)%20is%20an%20uncommon,are%20things%20that%20can%20help.





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Eating Ultra Processed Foods Has This Weird Effect On Your Brain

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Ultra-processed foods is a term we’re likely all familiar with: junk foods that have very little to no nutritional value. More specifically, the term refers to “industrial formulations of food substances (oils, fats, sugars, starch, and protein isolates) that contain little or no whole foods and typically include flavorings, colorings, emulsifiers, and other cosmetic additives,” according to a new study that found these foods are bad for our brains.

The study was presented at this week’s Alzheimer’s Association International Conference in San Diego and pointed out how these foods are linked to cognitive decline.

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The results of the study are concerning since ultra-processed foods can be easily packaged and disguised as healthy, particularly since they’re convenient and can save a lot of time for people, including frozen meals, hot dogs, ice cream, breads, crackers, and more.

Researchers in Brazil examined 10,000 middle-aged and older adults and found that those who consumed over 20% of their calories from processed foods experienced a faster decline in cognitive performance. In America, where diets are made up of 58% ultra-processed foods, this is very concerning.

RELATED: High Protein Diets May Hurt Your Heart

Previous studies have linked ultra-processed foods with a variety of diseases, from obesity to cardiovascular disease. This new study focused on the food’s effect on the mind and found that inflammation was the culprit.

“That’s because they cause inflammation, which can affect neurotransmitters in the brain. Processed foods also operate on a micro level with billions and billions of bacteria cells that (impair) functioning,” Rafael Perez-Escamilla, professor of public health at Yale University, told USA Today.

RELATED: Drinking This Popular Beverage Increases Your Odds Of Dementia

Ultra-processed foods are a serious problem in the US, being cheaper and easier to access than a large number of healthy, whole foods. They have longer shelf lives and are easier to cook, becoming a convenient option for people who don’t have the time to cook or are simply looking for cheaper options.

Still, it’s important for people to know this information on these types of foods, and to keep in mind that they take a toll in the long run, depriving you of years of health.



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High-Strength THC Balanced With CBD Is Better For Your Brain, Study Shows

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By Nina Zdinjak

CBD and THC are the two major compounds found in the cannabis plant that seem to have opposing effects on our brains.

According to a new study published in the Journal of Psychopharmacology, CBD can minimize some of the negative effects THC has on the brain.

Will Congress Boost Hemp Total THC Limit To 1%?
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RELATED: CBD And CBG Show Promising Results In Treating Glioblastoma Brain Tumors

“Cannabis is a very popular recreational drug, and is also starting to be used medically for some purposes, but we still don’t know a great deal about how different cannabinoids affect the brain,” study author Matt Wall, a senior imaging scientist at Invicro, told PsyPost.

Study Highlights

The researchers used data from another study that examined the brain activity of 17 healthy participants taking various marijuana strains (some high in both THC and CBD, others high in THC but without CBD, and placebo), using functional magnetic resonance imaging (fMRI).

In this new research, Wall and his colleagues measured brain activity in 23 healthy participants after they consumed oral CBD and a placebo. They also used fMRI to examine brain activity.

Results

The researchers revealed that THC and CBD have opposing effects. The first study confirmed the significant disruptive effect of both THC and THC + CBD on connectivity in the associative and sensorimotor networks, and also a certain effect of THC in the limbic striatum network that was not noticed with the combination of THC and CBD.

The second study showed CBD boosts connectivity in the associative network while causing relatively minimal disruptions in the limbic and sensorimotor networks.

In short, consuming marijuana strains with both THC and CBD should decrease striatum connectivity, but to a lesser extent than THC-only marijuana strain.

The findings suggest that “different types of cannabis have different effects on the brain,” Wall told the outlet. “High-strength, relatively pure-THC cannabis can severely affect some brain networks, but when THC is combined with cannabidiol (CBD) in a more ‘balanced’ way, these effects may be reduced somewhat, making a balanced strain of cannabis potentially safer to use. CBD by itself seems to have quite minimal effects on the brain networks we looked at, which means it’s probably safe for use as a potential therapy.”

Study Limitations

The two studies were both small, and need replication in larger groups, which Wall and his colleagues are currently exploring. “Also, we used data from two different cohorts of subjects here, so direct comparison between those two groups is not really possible,” he added.

RELATED: Marijuana & Brain: Can Cannabis Cause Psychiatric Disorders? Neuroscientist Weighs In

cannabis brain
Photo by Feodora Chiosea/Getty Images

Conclusions

Despite these limitations, the study can serve as a guideline on what future studies should be conducted, revealing the importance of truly understanding how different cannabis compounds affect our health. Scientific insights on these effects may help the public better understand cannabis-related disorders, as well as the development of cannabinoid therapeutics.

“Cannabis is transitioning to legal or semi-legal status in a lot of places around the world, and that means more people will potentially be exposed to cannabinoids,” Wall said. “Understanding the effects of different cannabinoids is a vital effort to ensure that people have the best information about the cannabis they use and can make well-informed choices.

This article originally appeared on Benzinga and has been reposted with permission.



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Does Medical Cannabis Work For Meningitis?

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This article originally appeared on Cannabis.net and has been reposted with permission.

Meningitis is a condition characterized by inflammation that occurs within the brain’s protective membranes. It’s caused by a viral or bacterial infection of the fluid around the brain and the spinal cord, which causes swelling.

Other possible causes of meningitis include drugs, injuries, various infections, and cancer. Because of the many possible causes of meningitis, there are several names for this condition including bacterial meningitis, viral meningitis, fungal meningitis, parasitic meningitis, and many others. The symptoms can show up within a few days or in as little as a few hours, and it can include fever, confusion, stiff neck, and severe headaches.

headache
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RELATED: CBD And CBG Show Promising Results In Treating Glioblastoma Brain Tumors

Bacterial meningitis can be extremely fatal if diagnosis and antibiotic treatment has been delayed. The longer treatment is delayed, the more it can cause permanent brain damage or even death. This condition has also been associated with other complications such as memory and hearing loss, learning difficulties (especially among children), kidney failure, problems with gait, and shock. According to the World Health Organization, untreated meningitis has a high fatality rate

Depending on the cause of the condition, treatment may vary though it usually includes intravenous antibiotics, corticosteroids, bed rest, and medications to counter the fever and body aches. However, due to the sensitive nature of this condition, the use of other alternative medications such as cannabis can help prevent further complications.

How Cannabis Helps

The human endocannabinoid system is responsible for helping suppress inflammation while improving neuroprotection and immunodilation. Even though there are very few studies documenting the use of cannabis specifically for meningitis, there have been other case studies suggesting that cannabis can be a powerful anti-inflammatory, antibacterial, and antiviral agent for treating the symptoms of this condition.

There’s a 2021 study, however, conducted by researchers at the University of Queensland together with Botanix Pharmaceuticals Limited. They found that cannabidiol (CBD), the non-psychoactive compound in marijuana, was effective in treating many different types of bacteria. “This is the first time CBD has been shown to kill some types of Gram-negative bacteria. These bacteria have an extra outer membrane, an additional line of defence that makes it harder for antibiotics to penetrate,” explains Dr. Blaskovich, Associate Professor at the University of Queensland.

“Our company is now primed to commercialize viable antimicrobial treatments which we hope will reach more patients in the near future. This is a major breakthrough that the world needs now,” he said. “Those Phase 2a clinical results are expected early this year and we hope that this will pave the way for treatments for gonorrhea, meningitis, and legionnaires disease,” he adds.

cannabis brain
Photo by Feodora Chiosea/Getty Images

RELATED: Can Cannabis Keep Your Brain Young?

Blaskovich has been involved in other similar studies, and in 2019 he presented the findings of his analysis on CBD for treatment-resistant bacteria. “The first thing we looked at is CBD’s ability to kill bacteria,” Blaskovich says. “In every case, CBD had a very similar potency to that of common antibiotics.” Together with his team, they looked at how CBD worked compared to common antibiotics such has daptomycin and vancomycin. “We looked at how quickly the CBD killed the bacteria. It’s quite fast, within 3 hours, which is pretty good. Vancomycin kills over 6 to 8 hours.”

They also discovered that CBD was effective in breaking the biofilm around bacteria which makes it harder for antibiotics to penetrate and thus kill it off.

In another study, researchers from the University of Southern Denmark led by Janne Kudsk Klitgaard, PhD, showed promising results of CBD treating antibiotic-resistant bacteria. For the study, they tested Staphylococcus aureus bacteria, a major pathogen that causes many types of diseases that cause people to be hospitalized. The researchers believe that combining CBD with antibiotics could be a novel treatment for infections especially for antibiotic-resistant cases. When the bacteria was given a combination of both, they were found to be unable to normally divide.

“Based on these observations, the combination of CBD and BAC is suggested to be a putative novel treatment in clinical settings for treatment of infections with antibiotic-resistant Gram-positive bacteria,” they wrote in their research paper. “With fewer antibiotics available to treat MDR bacterial infections, the possibility of entering a pre-antibiotic era is looming ahead,” they wrote.

Using Cannabis For Pain Management
Photo by Jesper Aggergaard via Unsplash

Symptoms of Meningitis

Medical marijuana can be used to help alleviate the painful and uncomfortable symptoms of meningitis as well. This is due to its potent neuroprotectant and anti-inflammatory properties from THC and as well as CBD. Since meningitis affects the brain and spinal cord, these benefits are important since cannabis can help reduce the potential of further damage, saving people’s lives.

Pain: Patients with meningitis struggle with extreme pain due to inflammation in the membranes that surround the brain and spinal cord. The exact way it works to treat pain is unknown although there are several hypothesis, such as the ability of cannabinoids to regulate our pain thresholds by acting on the nociceptors. It also reduces the production of cytokines to minimize the amount of pain we feel while decreasing inflammation, among many others.

Skin rashes: Some cases of meningitis are characterized by skin rashes, another symptom that cannabis can help with. CBD products can be applied topically to the affected area to treat with itching and inflammation, though it can also be taken orally to address inflammation from the inside.

Patients can also take cannabis to help address the depression and anxiety that often comes with this condition.

Given the great risk of fatality and serious brain damage that can occur with meningitis, it’s in the best interest of patients and their loved ones to maximize all the available alternative medications that can work well with conventional treatment.

This article originally appeared on Cannabis.net and has been reposted with permission.



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