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Shadow Banning Psilocybin Businesses: Local Governments May Rely on Development Code To Deny Permitting

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As we previously covered, Oregon counties and cities are currently considering whether to opt-out of Measure 109 and ban psilocybin manufacturers and service centers within their jurisdiction. Local governments automatically enroll into the Measure 109 program unless they refer an opt-out ordinance for approval to local voters in the upcoming November election. City and county governments may also refer ordinances with a sunset clause that essentially act as a temporary moratorium on psilocybin businesses to provide local governments the opportunity to develop time, place, and manner (TPM) restrictions.

In researching which local governments in Oregon are planning to refer opt-out ordinances to voters, we discovered another avenue local governments may use to prohibit psilocybin businesses in their area. Dallas, Oregon, is currently considering referring an opt-out ordinance to their voters and a staff report discussing the matter explains that the city could either refer a full opt-out ordinance to voters, refer a moratorium ordinance with a sunset clause, or:

A third and final option is to do nothing. If the Dallas Council elects this third option, city staff will rely on our development code provision requiring businesses to comply with federal, state and local laws. Since psilocybin is currently a schedule I drug, the city’s development code language would not allow us to permit psilocybin uses.

For those unfamiliar with land use law, development codes are promulgated by local governments to create zoning districts that determine what type of buildings and uses are allowed within a given area. A simple example is a city can ban construction of commercial buildings in areas zoned “residential,” and relegate construction of those buildings to other areas of the city that are reserved for commercial activity.

Dallas currently relies on its development code to outright deny permitting of marijuana businesses in the city, and the practice seems effective as there are currently no dispensaries in the town. The staff report prepared for the Dallas city council does note that legal challenges may arise should the city rely solely on its development code to prohibit psilocybin facilities. It is hard to predict the chance of success in challenging such a practice in court, but regardless, the possibility of local government using development codes in this fashion presents an additional barrier to opening psilocybin businesses in some parts of Oregon.

Accordingly, businesses should remain apprised of the development code in any jurisdiction they are thinking of purchasing real estate in to ensure there are no general prohibitions against issuing permits to business acting out of compliance with federal law. While it is unsettled whether local governments can rely on their development code in this way, it is another factor to consider in addition to the still unknown TPM restrictions that local governments will institute.

The Oregon Health Authority is expected to begin rulemaking on TPM regulations this September, and we will keep readers apprised of those regulations and any developments in the meantime that may affect your psilocybin business and real estate decisions.

Contact Brett Mulligan at info@gl-lg.com or (503) 488-5424.



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Amanita Muscaria

Psyched Wellness is Bringing You Amanita Mushrooms – And It’s All Legal

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Magic mushrooms are the new buzz word, but they don’t all fall into just one category. Sure, there are psilocybin magic mushrooms, but there are also amanita mushrooms, for a different kind of high and unique medical advantages. Now, the company Psyched Wellness is offering amanita mushroom products, and the best part is, it’s all legal.

We all know about psilocybin mushrooms, right? Well, now there’s a new mushroom to know about, Amanita muscaria, and these mushrooms are not only legal, but come with a host of medical benefits. If you’re into independent drug reporting concerning the cannabis and psychedelics fields, this is the publication for you. We provide the Cannadelics Weekly Newsletter so readers can stay updated on current events, as well as have access to tons of deals on cannabis products including popular cannabinoid compounds Delta 8 THC, and HHC, and all upcoming hallucinogenic products. Check the ‘best of’ lists for offers, and choose the products you’re most comfortable using.


What are amanita mushrooms?

When you hear the term ‘magic mushrooms’ the go-to association is with psilocybin mushrooms, the shrooms readily found in North and South America, which cause trips and highs by activating serotonin receptors. These mushrooms, along with LSD, DMT, and other compounds, are considered psychedelic hallucinogens.

This group of psychedelic hallucinogens doesn’t include other drugs we often think of as psychedelics, like ketamine. That drug, along with PCP and DXM are all dissociative hallucinogens. There is a third group as well, called deliriant hallucinogens, which includes scopolamine, the drug used to rob people by taking away their ability to argue with perpetrators. These three represent serotonergic, dopaminergic, and anticholinergic hallucinogens only.

This is where amanita mushrooms come in, as hallucinogens that act on a different neurotransmitter, GABA. Amanita muscaria mushrooms – AKA fly agaric, (for their ability to attract and trap flies), are also wild mushrooms that produce some trippy effects, but with an entirely different mode of action then psilocybin mushrooms. Amanita mushrooms are considered poisonous mushrooms, and contain a compound called muscimol, which is GABAergic. This means it acts as an agonist on GABA receptors, and does so in the same way as GABA itself; rather than attaching to different receptor sites like benzodiazepines, barbiturates, and Quaaludes.

amanita mushrooms
Amanita mushrooms

These mushrooms also contain ibotenic acid, which is the compound more likely to make a person sick. This compound is a prodrug (a compound which is biologically inactive until metabolization), and is metabolized in the body to become muscimol. This is similar to psilocybin, which is also a prodrug, and which is useless in the human body until it changes into the other compound found in magic mushrooms, and the real compound of interest, psilocin.

Whereas psilocin acts on serotonin receptors, creating a stimulant response along with its psychedelic effects, muscimol acts on GABA receptors that calm the body down. Amanita mushrooms therefore won’t cause the same kind of ‘bad trip’ as psilocybin mushrooms, since there’s no stimulant effect. They do, however, come with their own reasons for caution in how they’re prepared and eaten, so as not to make a user feel sick. Neither mushroom group is known to cause death (despite the name ‘poisonous’), so even a bad experience with either is only temporary.

Amanita mushrooms are less well-known in the Americas as they’re not native to this region. For the most part they’re found around Northern Europe and Russia (particularly Siberia), and factor into medicinal and shamanistic traditions in those regions. This is probably why they aren’t scheduled in the US Controlled Substances list, which makes them legal to have and use in the US.

A little about Psyched Wellness & Calm

Psyched Wellness is a publicly traded company on the Canadian Securities Exchange under (CSE:PSYC), which used to be Duncan Park Holdings Corporation. Based out of Toronto, Psyched Wellness is a life sciences company which just finished a pilot run for its new amanita mushrooms product, Calm.

This main offering of the company, Calm, is the first approved amanita mushroom product to hit US markets. According to the company, its made 100% from amanita mushroom caps, is lab tested, detoxified to ensure no bad effects (no ibotenic acid), and can be used to “reduce stress, ease muscular tension, and promote restorative sleep.” The company is taking preorders for the product right now, and interested buyers can reserve themselves a 1 fluid ounce bottle for $49.99. Products are expected to officially hit the market in the fall.

Calm registers as a dietary supplement, which is advertised as ethically sourced. The main component, according to the company’s site, is AME-1 which was developed in the Psyched Wellness laboratories to mimic the naturally extracted compound muscimol. It does not contain naturally occurring muscimol. As this is not a controlled substance, and doesn’t require a prescription, the company is free to sell it without the same complications that currently exist with psilocybin mushrooms, which are still federally illegal as they sit in Schedule I of the controlled substances list.

medical amanita mushrooms

The company is looking to expand its product offering in the future. According to CEO Jeffrey Stevens, “It has been a long journey to get to this point, and I would like to take this opportunity to thank my co-founder, David Shisel, our team, KGK Science and Vantage Hemp for all of their hard work and commitment to get us to where we are today. The most exciting part for me is that we have just scratched the surface with respect to potential uses and delivery forms for AME-1. Stay tuned for more to come from Psyched.”

Aside from this compound, the company also sells accompanying sweatshirts, bags, T-shirts, phone covers, water bottles, hats, and mugs, some emblazoned with the well-known image of the red capped mushroom with white spots. While Super Mario Brothers certainly kept this image alive for years, its new entrance into the US sales market is sure to give it an extra popularity boost in the near future.

A bit more on muscimol from amanita mushrooms

For many people, these mushrooms represent something completely new. Whereas psilocybin mushrooms have been used in the Americas for millennia, both for medical and recreational purposes, amanita mushrooms are not well-known to this part of the world. They are therefore a mystery to Americans in terms of what they can do, what to be wary of, and how they differ from standard magic mushrooms. In an interview with Technology Networks, Jeff Stevens gave some insight into these ‘other’ hallucinogenic mushrooms.

Of muscimol he says, “Muscimol is one of the main psychoactive compounds found in the Amanita muscaria mushroom along with ibotenic acid and muscarine. Although it does have psychoactive properties, the effect is very different from psilocybin or psilocin. It reacts with the GABAA receptor and when ingested, it can provide feelings of euphoria and tranquility, an altered sense of hearing and taste, changes to sensory perception and vivid dreams.”

He goes on to stipulate that “If it is not processed properly, where the ibotenic acid is not converted to muscimol, it can provide quite a nasty experience including sweating, nausea, loss of balance and involuntary bodily movements.” This helps explain how amanita mushrooms can cause negative effects, but don’t have to so long as the right usage techniques are employed.

In terms of why we’re only hearing about muscimol now, he says, “We believe the reason muscimol has not been studied to a large degree is because it has been mislabeled as poisonous and as such was overlooked. As a result, there’s not been a lot of scientific studies conducted on muscimol so groups like Psyched Wellness need to start from the ground up, making it more time consuming and more expensive.”

muscimol mushrooms
Muscimol

When it comes to the legality of the mushrooms, he explains, “Amanita muscaria are considered food and are principally regulated under the Federal Drug Act and the Consumer Packaging and Labelling Act in Canada and the Federal Food, Drug and Cosmetic Act and The Nutrition Labelling and Education Act in the USA. As a result, the challenges that other compounds face with extraction, regulation and or administration are not a factor.”

Psyched Wellness has been going over accumulated research on these mushrooms, looking for different applications. Says Stevens, “we believe muscimol could show positive indications for various mental and physical health issues, including sleep, insomnia, addiction and pain.”

Conclusion

Amanita mushrooms represent a different option in the world of hallucinogenic treatment. It’s not just about standard psychedelics anymore, and amanita mushrooms, with their main psychoactive constituent muscimol, offer an entirely different approach to helping with mental and physical health.

Hello and welcome! Thanks for making it to Cannadelics.com, a top platform for independent coverage of everything in the cannabis and psychedelics worlds. Read-thru the site daily for updates, and subscribe to the Cannadelics Weekly Newsletter, for news items and the best in product offerings.





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Psychedelics

SENATOR WIENER’S STATEMENT ON AMENDMENTS TO PSYCHEDELICS LEGISLATION AND FUTURE OF THE BILL

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SACRAMENTO – Senator Scott Wiener’s (D-San Francisco) released the following statement:

“I’ve now confirmed that SB 519 – decriminalizing possession and use of small quantities of certain psychedelic drugs – was amended by the Assembly Appropriations Committee to remove the decriminalization aspect of the bill.

As a result, the soon-to-be-amended version of SB 519 is limited to a study. While I am extremely disappointed by this result, I am looking to reintroducing this legislation next year and continuing to make the case that it’s time to end the War on Drugs.

Psychedelic drugs, which are not addictive, have incredible promise when it comes to mental health and addiction treatment. We are not giving up.”

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Psychedelic Alpha Report: “Compass “milked” researcher for trade secrets before “secretly” filing patent on same technology, alleges lawsuit”

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What with the MAPS “therapy” disaster followed by the ABC (Australia) Mind Medicine expose and now this, all in all it has not been a good month for those that believe in the future of a regulated psychedelics environment. Apply $’s to psychedelics and all sorts of problems occur…..Me thinks our counterculture hereos of the 60’s and 70′ would be laughing their socks off.

This week’s drama comes courtesy of Terran Biosciences, which alleged in a lawsuit filed on the 5th August that Compass Pathways stole trade secrets from a University of Maryland, Baltimore (UMB) researcher Dr. Scott Thompson then filed patents claiming them.

Why does Terran care? Well, in 2021 the stealth biotech company inked an exclusive licensing deal for a suite of psychedelic-related patents and data from UMB. Thompson’s work was among it.

Thompson researches methods of antidepressant drug action, and depression itself, in his role as professor of physiology at UMB. According to the lawsuit filed by Terran, Thompson has been working on the “idea of co-administration of psilocybin with a 5-HT2A antagonist” since 2016. The purpose of this co-administration would be to tamp down or eliminate the hallucinogenic effects of a psychedelic (in this case psilocybin) while maintaining any therapeutic (in this case antidepressant) effects.

Read the full report https://psychedelicalpha.com/news/psychedelic-bulletin-114-lawsuit-alleges-compass-stole-trade-secrets-mindmed-cmo-turns-activist-shareholder-california-decrim-bill-tentatively-clears-hurdle#:~:text=Psychedelic%20Sector%20News-,Compass,-%E2%80%9Cmilked%E2%80%9D%20researcher%20for

 

and then this…  

Exclusive: Tweet from Compass Account Calls Terran “slime” and Lawsuit “Publicity ploy” — Compass Blames Hac

In the course of writing-up tthe above story we felt that even mentioning the possibility of a fishing expedition on Terran’s part was overly cynical.

That’s until a tweet steeped in even more cynicism came to our attention. The tweet was posted in response to a thread we wrote as the news broke, and read:

Publicity ploy for Terran. What slime

What surprised us was that the tweet was posted from Compass Pathways’ Twitter account (ownership of the account was confirmed to Psychedelic Alpha in writing).

We reached out to Compass, who told us that “COMPASS did not make this comment”. A representative from the company went on to tell us that they would “assume we have been hacked”.

The tweet was deleted within minutes of being posted.



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