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What is Neuroplasticity and How Does Cannabis Help with That and Other Brain Health Issues?



neuroplasticity and cannabis

What Is Neuroplasticity? Why You Should Care, And How Cannabis Contributes To It


Neuroplasticity is the medical term given to the brain’s ability to adapt and changed based on its environment and experience. The neural networks in the brain can change, organize themselves, and even grow new connections because of its malleability.


It is known that younger brains, such as those of children, are generally more malleable. Their brains are more sensitive to experience compared to those of older adults. Aging causes the brain to degenerate over time, due to the lack of brain cells, leading to disorders such as Alzheimer’s. However, science tells us that older adults are still capable of experiencing neuroplasticity especially with the help of cannabinoids. Our very own brain contains cannabinoid receptors too, so when we consume cannabinoids, studies show that it can help create new brain cells, forge new synapses, and ensure the viability of existing brain cells.


Certain negative experiences such as stress, trauma, and depression can weaken the synapses in the brain, resulting in impaired memory, learning, and overall plasticity. Meanwhile, physical conditions such as strokes, inflammation (due to diet or exposure to stress), traumatic brain injuries (TBI) and others can also impair the brain’s ability to heal itself and forge new connections.


Again, that’s where cannabis can help.


Here’s what the studies have to say:


Cannabinoids Reduce Plaque Proteins Which Leads to Alzheimer’s Disease


A 2016 study conducted by researchers at the La Jolla Salk Institute discovered that tetrahydrocannabinol (THC) as well as other cannabinoids can help get rid of amyloid beta, a protein considered as toxic because its accumulation can lead to Alzheimer’s disease especially in aging brains. The presence of amyloid beta is a hallmark feature of Alzheimer’s.


“Although other studies have offered evidence that cannabinoids might be neuroprotective against the symptoms of Alzheimer’s, we believe our study is the first to demonstrate that cannabinoids affect both inflammation and amyloid beta accumulation in nerve cells,” explains senior author David Schubert.


They also found that high levels of amyloid beta have been linked to cellular inflammation and higher risk for neuron death.


Cannabis Protects Neurons In Injured Brains and Traumatic Brain Injury (TBI)


A 2012 study involved researchers causing injuries on purpose, to the brains of rodent subject. They did this through repeated exposure to MDMA, carbon monoxide, and pentobarbital.


The rodents were administered with one low dose of THC, following the ratio of .002mg per kilogram of body weight. They found that just one low dose was protective against any damage to neurons, which are the cells in the nervous system responsible for transmitting signals and aiding us in memory, thinking, movement, and other cognitive functions.


A 2019 study that was published in the medical journal, Brain Injury, found that while cannabis use had no impact on the recovery time for those who suffered concussions, it was linked to a reduction in symptom burden especially during the 3rd and 4th weeks following injury.


Additionally, a July 2020 literature review stated that “the use of cannabinoids in TBI increases neurobehavioral function and working memory performance.” They explain that it does this through the “down-regulation of pro-inflammatory markers, edema formation and blood-brain barrier permeability, preventing neuronal cell loss and up-regulating the levels of adherence junction proteins.”


Cannabis Aids In Neurogenesis


Neurogenesis is the name given to the process of creating new brain cells. Neurogenesis plays an important role in improving synaptic plasticity, regulating our moods, and better memory.


There have been several studies proving how cannabis contributes to neurogenesis. In one study out of Italy, scientists discovered that cannabichromene (CBC), one of the lesser known cannabinoids in marijuana, can actually contribute to the growth of brain cells through neurogenesis.


In another study conducted by researchers from the University of Saskatchewan in Canada, they sought to understand how cannabinoids impact the brain. Mice were injected with a synthetic drug called HU210, which is 100 times more potent than THC. A chemical tracer was then used to monitor the growth of any new cells. They found that HU210 was effective in promoting the growth of new brain cells, similar to how antidepressants work. “Most ‘drugs of abuse’ suppress neurogenesis,” says Dr. Zhang, who participated in the study. “Only marijuana promotes neurogenesis.”


Other studies show that cannabidiol (CBD) is just as beneficial as THC for the brain, but both CBD and THC have neurogenic properties. “The pro-neurogenic effects of CBD might explain some of the positive therapeutic features of CBD-based compounds,” report German scientists back in 2010. In addition, CBD and THC have antidepressant properties, as well as other compounds in the cannabis plant, which help humans adapt to exposure to stress and injury.


Cannabis Aids In Healing of Mental Health Disorders


Many mental health disorders are affected by neuroplasticity. For one, post-traumatic stress disorder, which is characterized by recurrent nightmares, severe anxiety, and flashbacks. Trauma can change the actual structure of one’s brain, so there is a physical explanation to the changes in how the brain works.

Studies show that cannabis can help heal the brain and in doing so, help individuals heal from PTSD. A recent study revealed that CBD can boost blood flow to the brain, and positively affect memory processing. “There is evidence that CBD may help reduce symptoms of psychosis and anxiety. There is some evidence to suggest that CBD may improve memory function,” says the study’s lead author, Dr. Michael Bloomfield.


“Additionally, CBD changes how the brain processes emotional memories, which could help to explain its reputed therapeutic effects in PTSD and other psychiatric disorders,” he adds.




With all the valuable mechanisms that cannabis can help the human brain, it certainly is an excellent all-natural way to support our cognitive functions while also healing from emotional distress or brain injury. Making cannabis a part of your wellness regimen is a great way to give your brain the support it needs.






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You Got Arrested for Weed, But Now Qualify for a Pardon, How Do You Apply? (Canadian Version)




Applying for a cannabis pardon can be daunting, but it is essential to a brighter future. Due to their criminal record, many people with cannabis-related convictions may face barriers to employment, housing, and other opportunities. A pardon can help remove these barriers and provide a second chance for those who have paid their debt to society.

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New York Cannabis: Social and Economic Equity Applicants




As we previously broadly summarized on December 27, 2022 (here), in late December 2022, the Office of Cannabis Management (“OCM”) released its first proposed adult-use cannabis rules and regulation for New York (the “Proposed Regulations”). The official document is 282 pages, so we won’t cover every detail. But we will highlight the big-ticket items, significant issues that all applicants should be aware of, and the license application process as a whole.  This post will go into detail the Social and Economic Equity sections and commentary provided for in the Proposed Regulations.  Keep in mind, the Proposed Regulations are still pending as OCM receives the final public comments to the Proposed Regulations.

For anyone considering applying for an adult-use license, we reiterate our recommendation of hiring an experienced, local cannabis attorney. At a minimum, understanding the overall framework of the licenses and the licensing process is a precursor to an in-depth consultation on a license application.

One of the more notable topics covered in depth by the Proposed Regulations is the establishment of a social and economic equity applicant, and licensee. If you remember, the Marijuana Regulation and Tax Act (“MRTA”) established a goal to award 50% of all adult-use cannabis licenses to social and economic equity applicants.

During the evaluation of an application, the OCM may prioritize application submission, review, selection and issuance by social and economic equity status. Those applications that demonstrate that the applicant is seeking to qualify as a social and economic equity licensee are eligible for extra priority.

In short, to qualify as a social economic equity applicant, an applicant must demonstrate, through documentation provided to the OCM, that that sole control of the applicant is held by either:

  1. an individual from a community disproportionately impacted by the enforcement of cannabis prohibition;
  2. a minority-owned business;
  3. a women-owned business;
  4. a distressed farmer; or
  5. a service-disabled veteran owned business.

The Proposed Regulations provide for specific documents required to establish the status of the social economic applicant, with respect to any of the above.

Note that “sole control” in this context may be a misnomer. It does not mean that the applicant is the sole owner of the license, but that the social and economic equity applicant exercises the authority to, among other things: exercise authority over the business, and materially influence the day-to-day business decisions. Further, no other person or persons may exercise or have the ability to control the majority of voting rights, or remove the applicant.

If, at any time after a social and economic equity applicant has been granted a license, the Office determines that the sole control requirement is violated, the Office may institute an action to suspend or revoke such license, provided the Office provides an opportunity to cure.

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Cannabis and Orgasm Inequality – Solving the Dry Partner Phenomenon You Never Knew About!




cannabis orgasm men vs. women

cannabis orgasm men vs. women

Cannabis and Orgasm Inequality – The Problem you didn’t know existed!


A recent article in Marijuana Moment brought to my attention the problem of “Orgasm Inequality”. It covered a study that was led by Amanda Moser of East Carolina University and published in the Journal of Cannabis Research.


The Denver-based sexologist, surveyed 811 adults who have used cannabis and found that greater perceived sexual functioning and satisfaction can be achieved regardless of age or gender.


It appears that cannabis is a true aphrodisiac, with over 70% of participants reporting increased desire and improved orgasms when using cannabis before sex. And for those who prefer solo play, cannabis also enhances pleasure with 62.5% of participants reporting enhanced pleasure while masturbating.


But the study’s findings are especially relevant for women’s pleasure. The results “suggest that cannabis can potentially close the orgasm inequality gap,” the authors write, referring to past findings that women who have sex with men are typically less likely to orgasm than their partners.


So, ladies and gentlemen, next time you’re looking to spice things up in the bedroom, consider reaching for some cannabis.



Orgasm inequality refers to the disparity in the likelihood of men and women experiencing orgasm during sexual activity.


Studies have shown that men are more likely to orgasm during sexual intercourse than women. Of course, we don’t really need studies to prove that men cum quicker. This phenomenon is often referred to as the “orgasm gap” and can be attributed to a variety of factors, including societal and cultural influences, lack of education and communication about sexual pleasure, and biological differences between men and women.


Here’s a few more reasons why women aren’t cumming as often as men:


  • Lack of Communication: One of the most common reasons why women don’t experience orgasm during sex is due to a lack of communication between partners. This could include not knowing what feels good for the woman, not understanding her sexual preferences, or not being comfortable enough to express these desires.


  • Physical Factors: Certain physical factors can also play a role in preventing women from experiencing orgasm during sex. These can include pain during intercourse, vaginal dryness, or other health conditions such as vaginismus which causes spasms of the vaginal muscles that can make intercourse uncomfortable or impossible.


  • Psychological Factors: Psychological factors can also play a role in preventing women from experiencing orgasm during sex. These can include stress, anxiety, or past experiences that have left a negative impact on the woman’s sexuality. Additionally, women with low self-esteem, or body image issues may also find it hard to orgasm.


However, I believe that the main reason is because their partners don’t know how to please them. This is because most men are eager to get “off” and get on with their lives. Especially in a world of “one night stands”.


Yet when you “know what you’re doing” and you understand how to touch your partner…you can actually get women to cum quicker than men. In fact, you can give a woman multiple orgasms prior to even inserting your member into her cave of passion. Not to mention, some women can even experience orgasm via a story…literally, you could tell them how you’re gonna make them cum and they can do the rest.


However, most men are not such considered lovers but it seems that cannabis has the ability to mend this gap. But how exactly can a plant-based substance help close this divide? The answer lies in a combination of factors that work together to create a more satisfying sexual experience for everyone involved.


First, cannabis has a reputation for making people less self-conscious and more relaxed. For women, this can mean feeling less inhibited and more comfortable expressing their desires. For men, it can mean being more attuned to their partners’ needs and responding accordingly.


Second, cannabis is known to enhance the senses, particularly taste, touch, and smell. This can lead to a more immersive and pleasurable sexual experience, as the body is able to fully engage with the sensation of touch and the other person’s presence.


Third, cannabis has been shown to help people “match frequency” with their partners, both physically and mentally. This can lead to a deeper connection and understanding, as well as a more satisfying sexual experience for both parties.


So, next time you’re looking to spice up your sex life, consider reaching for a little bit of the green stuff. With its ability to make us less self-conscious, more attuned to our partners, and more in tune with our own bodies, cannabis just might be the key to closing the orgasm gap once and for all.


So get stoned and get boned!







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