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Are Psychedelics the Fountain of Youth?

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Dr. Andrew Steele, a physics professor who has ventured into the field of biology, presents a fascinating perspective on longevity in his new book. He emphasizes that it’s not cancer or heart disease but aging that is the root cause of the most significant suffering and deaths worldwide. Dr. Steele proposes that by finding pharmacological remedies that target the cells responsible for degrading tissue function, we could unlock the potential for humans to live up to 200 years old.

 

A group of Harvard Medical School researchers has uncovered a groundbreaking finding that sheds new light on aging. In an unprecedented international study, the team discovered that alterations to the organization and regulation of DNA, known as epigenetics, can trigger aging in an organism, regardless of any genetic code changes. Their research revealed that a disruption in epigenetic information leads to aging in mice, and when the integrity of the epigenome is restored, the signs of aging are reversed.

 

According to David Sinclair, a professor of genetics at Harvard Medical School and co-director of the Paul F. Glenn Center for Biology of Aging Research, the recent discovery reinforces the notion that mammalian cells possess a backup copy of epigenetic software. By accessing this backup, it may be possible to rejuvenate aging cells and restore them to a more youthful and healthy state.

 

As reported in the Genetics Literacy Project, pursuing molecules capable of reversing the aging process is expected to attract tens of billions of dollars in research funding. Sinclair, who also heads Life Biosciences, a biotech firm that focuses on developing therapeutics to prevent, treat, and potentially reverse age-related diseases, is leading this effort to extend the human lifespan.

 

Psychedelics to Become a Significant Substance of Focus

The Longevity Science Foundation (LSF) made an exciting announcement at the Wonderland 2022 conference in November. The nonprofit organization, committed to funding research to promote a prolonged and healthier human lifespan, revealed a new funding initiative for psychedelics research. This new project is a collaboration between the LSF and PsyMed Ventures, a company focused on investments in the psychedelics sector.

 

The Longevity Science Foundation (LSF) reports that the use of psychedelics for mental health treatments is gaining momentum at an unprecedented pace. Compounds such as MDMA, ketamine, and psilocybin have demonstrated encouraging outcomes in treating PTSD, depression, and addiction. In addition, researchers have shown that ketamine and psilocybin may assist in regenerating neural connections, which could have far-reaching implications in the development of treatments for neurodegenerative disorders associated with aging, as per the LSF.

 

The LSF has pledged $1 billion in research funding, institutional support, and project financing over the next decade to support its mission to promote healthy human longevity. As part of this initiative, the foundation is looking to back psychedelics companies that are engaged in research aimed at managing, delaying, or even reversing age-related mental and brain diseases, investigating the mechanisms underlying the effects of psychedelic compounds, or other pioneering studies that have relevance to both the longevity and psychedelics fields.

 

The Healthy Longevity Medicine Society (HLMS), a partner of LSF, has set itself the goal of creating, coordinating, and promoting a comprehensive clinical research program that covers all facets of longevity medicine. The society intends to initiate various programs, such as the standardization of diagnostics and the creation of a clinical trial network.

 

Researchers have discovered drugs that can prolong the lifespan of animals, and one of LSF’s partners, rapamycin, has demonstrated the ability to prevent aging in mice. The drug has been found to reduce cognitive decline and delay the onset of Alzheimer’s disease, according to the LSF.

 

Scientists have discovered that a drug utilized to fight leukemia, when combined with a natural chemical substance derived from plants, exhibits the potential to lengthen human life. In addition, metformin, a drug that has been prescribed for diabetes for decades, is also demonstrating promise in the field of lifespan extension research.

 

Psychedelic therapy is finally getting recognition as a legitimate treatment option.

The executive coordinator of the LSF, Garri Zmudze, emphasizes the importance of mental health in longevity, stating that a healthy mind is just as crucial as a healthy body. The LSF’s funding of psychedelic research contributes to a growing body of knowledge transforming brain health and longevity.

 

Psychedelics researchers are exploring the potential role of psychedelics in extending life by examining their effects on neurons. The brain’s ability to change throughout life, known as neuroplasticity, is thought to be a critical component of life extension. Neuroplasticity involves changes in cell structure, structural plasticity, and alterations in the efficacy of synaptic transmission, also known as functional plasticity.

 

The ability of psychedelics to repair atrophied neurons, which occurs in depressed patients, results in improved synaptic connections or cell-to-cell communication. Experimental studies with LSD, ayahuasca, and psilocybin in placebo-controlled settings have shown positive results in reducing symptoms of depression, anxiety, and addiction after just one or two doses, with measurable effects lasting between three weeks and six months. Researchers believe that the persistence of psychological effects beyond the presence of the substance in the blood suggests a biological adaptation.

 

Researchers have suggested that psychedelics may have an anti-aging effect, albeit more related to personality changes. With up to 20% of the world’s population projected to be over 60 years old by 2050, research into aging is a critical scientific pursuit. However, the ultimate goal remains unclear: will the research lead to therapies to prevent diseases or directly target extending lifespan?

 

Sinclair has predicted that reversing human aging may happen as soon as 2025. Reportedly, psychedelic businesses are showing interest in the work of Sinclair, who has secured a remarkable $158 million in funding for Life Biosciences.

 

Conclusion

The psychedelics field has long been dedicated to discovering new therapies for medical issues that have yet to be addressed. Eleusis, a company in this industry, is focusing on the impact of aging and has discovered that LSD may help treat cognitive decline related to Alzheimer’s disease.

 

Their research indicates that aging is linked to decreased neuroplasticity and that age is a crucial risk factor for dementia. “The decline in neuroplasticity that comes with aging may play a significant role in the loss of synapses and neurons in Alzheimer’s disease,” Eleusis explains.

 

PSYCHEDELICS FOR HEALTH, READ ON…

PSYCHEDELICS FOR MENTAL HEALTH FORM

PSYCHEDELICS FOR MENTAL HEALTH, WHICH ONES ARE WORKING RIGHT NOW!



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The Grinch Stole SAFE Banking from the Cannabis Industry This Christmas, Yet Again!

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no safe banking in 2024

The landscape of cannabis legislation in the United States has been a complex and evolving issue, particularly concerning banking regulations. As of December 2024, it has become official: the current Congress will not provide any protections for banks that serve state-legal marijuana businesses. This decision has significant implications for the cannabis industry, which continues to grow rapidly despite the lack of federal support. In this article, we will explore the reasons behind this decision, the implications for cannabis businesses, and the broader context of cannabis legalization in America.

 

The State of Cannabis Legalization

 

 A Growing Industry

 

The cannabis industry has seen remarkable growth over the past decade. As of late 2024, 23 states and Washington D.C. have legalized recreational marijuana use, while 38 states allow medical marijuana. According to recent estimates, the legal cannabis market in the U.S. is projected to reach over $40 billion by 2025. This growth has been fueled by changing public perceptions of marijuana, increased advocacy for legalization, and significant tax revenues generated by state-legal cannabis sales.

 

 The Banking Dilemma

 

Despite this rapid expansion, cannabis businesses face unique challenges, primarily due to their inability to access traditional banking services. Federal law classifies marijuana as a Schedule I controlled substance under the Controlled Substances Act. This classification creates a significant barrier for banks and financial institutions that wish to work with cannabis businesses, as they risk federal penalties for facilitating transactions related to an illegal substance.

 

As a result, many cannabis companies operate on a cash-only basis. This situation not only poses safety risks—such as increased theft and violence—but also limits these businesses’ ability to manage finances effectively, pay taxes electronically, and build credit histories.

 

 Legislative Attempts at Reform

 

One of the most prominent legislative efforts aimed at addressing these banking issues is the Secure and Fair Enforcement (SAFE) Banking Act. First introduced in 2019, the SAFE Banking Act sought to provide protections for banks that serve legal cannabis businesses by preventing federal regulators from penalizing them for doing so.

 

The act garnered significant bipartisan support in both the House and Senate. In previous sessions of Congress, it passed multiple times in the House but faced hurdles in the Senate due to opposition from certain lawmakers who were concerned about broader implications of marijuana legalization.

 

In light of ongoing discussions about federal spending and budgetary priorities, advocates had hoped that some version of the SAFE Banking Act would be included in recent spending bills. However, during negotiations leading up to December 2024, a House committee led by Republicans removed any provisions related to marijuana banking protections from key spending legislation.

 

This decision reflects a broader trend within Congress where discussions around cannabis reform have become increasingly contentious. While there is still bipartisan support for certain aspects of cannabis legislation—particularly when it comes to medical use—more comprehensive reforms like banking protections have struggled to gain traction.

 

 Implications for Cannabis Businesses

 

Continued Cash-Only Operations

 

The removal of banking protections means that many cannabis businesses will continue to operate primarily on a cash basis. This situation presents several challenges:

 

  • Safety Risks: Cash-only operations make cannabis dispensaries and cultivation facilities prime targets for theft and robber Employees often have to handle large amounts of cash daily, increasing their risk of violence.

 

  • Operational Inefficiencies: Without access to banking services, businesses cannot easily manage payroll or pay bills electronically. This inefficiency can lead to operational delays and increased costs.

 

 

 

Impact on Public Safety

 

Advocates argue that providing banking access would enhance public safety by reducing the amount of cash circulating within the community. By allowing cannabis businesses to deposit their earnings into banks, it would minimize the risks associated with cash transactions, making both employees and customers safer.

 

Moreover, having a transparent financial system would help law enforcement track illicit activities more effectively. Currently, without proper banking oversight, there are concerns that some cash-only operations may be involved in money laundering or other illegal activities.

 

Politics and Public Opinion

 

Changing Attitudes Toward Cannabis

 

Public opinion on marijuana legalization has shifted dramatically over recent years. According to various polls, a significant majority of Americans now support legalizing marijuana for both medical and recreational use. This shift has put pressure on lawmakers to address outdated federal policies regarding cannabis.

 

Despite this growing acceptance among the public, political divisions remain strong within Congress regarding how best to approach cannabis reform. Some lawmakers advocate for full legalization at the federal level, while others prefer a more cautious approach that prioritizes regulation over outright legalization.

 

 The Role of Advocacy Groups

 

Advocacy groups play a crucial role in pushing for legislative change regarding cannabis banking protections. Organizations such as the National Cannabis Industry Association (NCIA) and Americans for Safe Access (ASA) have been vocal proponents of reforming banking laws to support state-legal cannabis businesses.

 

These groups have mobilized public support through campaigns highlighting the safety risks associated with cash-only operations and advocating for policies that promote financial inclusion for cannabis entrepreneurs.

 

Future Prospects for Cannabis Banking Reform

While current congressional efforts have stalled regarding marijuana banking protections, there are still potential avenues for reform:

 

 

  • Incremental Reforms: Rather than pursuing comprehensive federal legislation like the SAFE Banking Act all at once, lawmakers may consider incremental reforms that address specific issues related to banking access without fully legalizing marijuana at the federal level.

 

 

The Role of Public Awareness

 

As public awareness about the challenges faced by cannabis businesses grows, there may be increased pressure on lawmakers to act decisively on this issue. Continued advocacy efforts can help ensure that banking reform remains a priority on Congress’s agenda.

 

Conclusion

 

The decision by Congress not to include marijuana banking protections in its current spending bill underscores ongoing tensions surrounding cannabis legislation in America. While public opinion increasingly favors legalization and reform, political divisions continue to hinder progress on critical issues such as banking access for state-legal marijuana businesses.

 

As the industry continues to grow despite these challenges, stakeholders must remain vigilant in advocating for change while exploring alternative solutions at both state and federal levels. The future of cannabis banking reform remains uncertain; however, with continued advocacy and public support, there is hope that meaningful progress can be made in addressing these pressing issues facing one of America’s fastest-growing industries.

 

SAFE BANKING SINCE 2018, WHAT A FAILURE, READ ON…

SAFER BANKING ACT FAILS AGAIN

SAFER BANKING ACT FAILS AGAINS, SAME OF BANANA IN THE TAILPIPE!



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HHC vs. Delta 9: Differences & Similarities

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Cannabis has so many compounds, and two that have been making the rounds lately are HHC and Delta 9 THC. They’re not the same thing, even though they’re both cannabinoids that interact with the body’s endocannabinoid system. Some people want a mild, steady experience, while others might be looking for something more intense. Understanding these two can help you figure out what’s right for you.

What Is HHC?

HHC, short for hexahydrocannabinol, is a hydrogenated version of THC. It’s not something you’d find naturally in large amounts in cannabis plants. Instead, it’s made through a process that adds hydrogen molecules to THC. The result? A more stable compound that’s less prone to breaking down when exposed to heat or UV light.

How HHC Is Made

Think of it like a science experiment. HHC is usually created in a lab by taking Delta 9 or Delta 8 THC and using hydrogenation—basically, combining it with hydrogen under pressure and in the presence of a catalyst. This process changes its structure while keeping its effects somewhat similar to THC.

Common Uses and Effects of HHC

People who use HHC say it’s somewhere between Delta 8 and Delta 9 in terms of effects. It’s often described as relaxing but without being overly sedative. You might feel a light buzz, reduced stress, or mild euphoria. Some even claim it helps with discomfort or improving sleep, but solid research is still catching up. Since it’s less potent than Delta 9, it’s often favored by those who want a manageable experience without the strong psychoactive punch.

If you’re interested in trying HHC and Delta 9 for yourself, check out their wide range of products at trycandycloud.com. They’ve got everything from gummies to disposable vapes, all crafted for a smooth experience.

What Is Delta 9 THC?

Delta 9 THC is the main psychoactive compound in cannabis. It’s the reason you feel “high” when you use weed. Chemically speaking, Delta 9 has a double bond in its ninth carbon chain, which plays a big role in how it interacts with your brain.

Natural Occurrence in Cannabis

This one is straightforward: Delta 9 is found in high concentrations in marijuana plants. It’s what most people think of when they hear “THC.” Unlike HHC, there’s no need for a lab process—it’s already there. Hemp plants, however, contain much lower levels of Delta 9 THC, which is why it’s primarily extracted from marijuana.

Common Uses and Effects of Delta 9 THC

The effects of Delta 9 are well-documented. Depending on the dose, you might feel euphoria, increased appetite, or deep relaxation. For medical users, it’s often used to manage chronic pain, nausea, and other conditions. It’s also been studied for its potential benefits in anxiety relief, though higher doses might have the opposite effect, causing paranoia. Delta 9 THC is versatile, but it’s not without its risks, particularly for new users or those sensitive to its psychoactive effects.

Key Differences Between HHC and Delta 9 THC

Chemical Structure and Composition

The main difference is in their structure. Delta 9 THC has that iconic double bond, while HHC’s hydrogenation makes it more stable. This difference might not mean much to the average person, but it’s why HHC is less likely to degrade over time.

Potency Levels

Delta 9 THC is generally more potent. HHC might require a higher dose to get a comparable effect, but some people prefer its lighter touch. Potency differences can also depend on the method of consumption, with edibles typically providing a stronger, longer-lasting effect compared to vaping or smoking.

Duration of Effects

Both last a few hours, but some users report that HHC’s effects fade more gradually. Delta 9, on the other hand, can have a sharper comedown. HHC’s gradual fade makes it appealing for those who want a smooth end to their experience.

Benefits and Drawbacks of HHC and Delta 9 THC

HHC: Pros and Cons

Pros:

  • More stable, so it lasts longer on the shelf.
  • Effects are milder, making it less overwhelming for beginners.
  • Can be a functional option for daytime use.

Cons:

  • Limited research, so we don’t know its full impact yet.
  • Availability can be hit or miss depending on where you live.
  • Legal gray area in many regions.

Delta 9 THC: Pros and Cons

Pros:

  • Well-studied with established medical uses.
  • Widely available in areas where cannabis is legal.
  • Stronger effects make it ideal for experienced users or those with high tolerance.

Cons:

  • Higher chance of side effects like anxiety.
  • More likely to show up on drug tests.
  • Shorter shelf life compared to HHC.

Frequently Asked Questions (FAQ)

Q. Is HHC safer than Delta 9 THC?

Not enough research exists to say definitively, but HHC’s milder effects might make it feel safer to some users.

Q. Will HHC or Delta 9 THC show up on a drug test?

Yes, both can potentially show up on a drug test, so use with caution if that’s a concern.

Q. Which one is better for recreational use?

That depends on your preferences. HHC is great for a mellow time, while Delta 9 is better if you’re looking for something more intense.

HHC vs. Delta 9: Choosing the Right One for You

The choice comes down to what you’re after. If you want a milder, more laid-back experience, HHC might be a good option. On the other hand, if you’re looking for something stronger or need it for medical reasons, Delta 9 is the way to go. It also depends on what’s legal and available where you are. And always consider your tolerance levels and experience before diving in. If you’re unsure, consult with a knowledgeable dispensary staff.

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What Federally Illegal Drug Has Created Almost $10 Billion in Sales Tax Revenue for States in the Last 40 Months?

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sales tax revenue with marijuana

In a significant development for the burgeoning cannabis industry, the U.S. Census Bureau has reported that states across the nation have collectively amassed over **$9.7 billion** in tax revenue from marijuana sales since mid-2021. This figure underscores the economic impact of legalized cannabis and highlights the growing acceptance of marijuana as both a recreational and medicinal substance in various states. As more states move toward legalization, the financial implications both positive and negative are becoming increasingly evident.

 

 The Landscape of Cannabis Legalization

 

The journey toward cannabis legalization in the United States has been long and complex. Initially criminalized in the early 20th century, cannabis began to regain acceptance in the late 20th century, particularly for medical use. The first state to legalize medical marijuana was California in 1996, setting a precedent that many states would follow.

 

By 2012, Colorado and Washington became the first states to legalize recreational cannabis, paving the way for a wave of legalization efforts across the country. As of now, more than 20 states have legalized recreational marijuana, while over 30 states allow medical use. This shift reflects changing public attitudes toward cannabis and recognition of its potential benefits.

 

Economic Implications of Legalization

 

The legalization of cannabis has not only transformed social norms but has also created a substantial economic impact. States that have embraced legalization have seen significant increases in tax revenue, job creation, and investment opportunities.

 

According to the latest Census Bureau report, states like California, Colorado, Illinois, and Michigan have emerged as leaders in cannabis tax revenue generation. These states have implemented various tax structures on marijuana sales, including excise taxes, sales taxes, and local taxes. The revenue generated is often earmarked for essential public services such as education, healthcare, infrastructure improvements, and drug rehabilitation programs.

 

Breakdown of Tax Revenue by State

 

 

As the largest legal cannabis market in the United States, California has been at the forefront of marijuana tax revenue generation. Since mid-2021, California has contributed approximately $2.5 billion to state coffers from cannabis taxes. This revenue is derived from both recreational and medical marijuana sales.

 

California’s tax structure includes a 15% excise tax on retail sales, along with local taxes that can vary significantly by city and county. The state has allocated a portion of these funds to various programs aimed at addressing issues related to drug abuse and public health.

 

 

Colorado was one of the pioneers in cannabis legalization and continues to serve as a model for other states. Since mid-2021, Colorado has generated around $1.8 billion in tax revenue from marijuana sales. The state imposes a 15% excise tax on wholesale marijuana transactions and a 2.9% sales tax on retail sales.

 

The revenue generated from cannabis taxes has been instrumental in funding education initiatives through the Public School Fund, as well as supporting mental health programs and substance abuse treatment services.

 

 

Illinois has seen remarkable growth in its cannabis market since legalizing recreational use in January 2020. In just two years, Illinois has collected approximately $1 billion in tax revenue from marijuana sales. The state imposes a tiered excise tax based on the potency of the product, ranging from 10% to 25%.

 

The funds collected are allocated to various initiatives, including community reinvestment programs aimed at addressing social equity issues related to past drug enforcement practices.

 

 

Michigan’s cannabis market has also flourished since legalization. Since mid-2021, Michigan has generated about $700 million in tax revenue from marijuana sales. The state’s tax structure includes a 10% excise tax on recreational marijuana and a 6% sales tax.

 

The revenue is utilized for various purposes, including education funding and support for local governments impacted by legalization.

 

Broader Economic Impact

 

 

The legalization of cannabis has led to significant job creation across various sectors. According to industry reports, the legal cannabis market supports hundreds of thousands of jobs nationwide—from cultivation and processing to retail and distribution. As more states legalize marijuana, this trend is expected to continue.

 

 

With the growth of the legal cannabis industry comes increased investment opportunities. Entrepreneurs are entering the market at an unprecedented rate, leading to innovations in product development, marketing strategies, and distribution channels. This influx of investment not only benefits individual businesses but also stimulates local economies.

 

Social Equity Considerations

 

While the financial benefits of cannabis legalization are clear, it is essential to address social equity issues that arise alongside this new industry. Many states have recognized that communities disproportionately affected by past drug enforcement policies should benefit from legalization efforts.

 

 

States like Illinois have implemented community reinvestment programs that allocate a portion of cannabis tax revenues to support communities impacted by previous drug laws. These funds can be used for education initiatives, job training programs, and mental health services—aiming to rectify historical injustices associated with cannabis prohibition.

 

 

In addition to financial support for communities affected by past policies, some states are also working to create equitable licensing opportunities for individuals from those communities. By prioritizing applications from minority-owned businesses or those directly impacted by previous drug laws, states can foster a more inclusive cannabis industry.

 

 Challenges Ahead

 

Despite the significant progress made through legalization efforts, challenges remain on both state and federal levels.

 

Federal Legalization Uncertainty

 

One major hurdle is the ongoing conflict between state and federal laws regarding cannabis. While many states have legalized marijuana for recreational or medical use, it remains classified as a Schedule I substance under federal law. This discrepancy creates complications for businesses operating legally at the state level but facing potential federal prosecution.

 

Efforts toward federal legalization or decriminalization have gained traction recently; however, progress remains slow due to political divisions and differing opinions on drug policy reform.

 

Regulatory Hurdles

 

As more states enter the legal cannabis market, regulatory frameworks must evolve to ensure consumer safety while promoting fair competition among businesses. States face challenges related to product testing standards, labeling requirements, advertising restrictions, and taxation policies that can impact market dynamics.

 

Conclusion

 

The U.S. Census Bureau reports that states have collected over $9.7 billion in marijuana tax revenue since mid-2021, highlighting the significant economic impact of cannabis legalization. As public acceptance grows, more states are likely to pursue legalization. Despite ongoing challenges, including federal regulations and social equity issues, legalized cannabis is poised to remain a vital part of state economies. Collaboration among government officials, business leaders, and community advocates will be essential for fostering an equitable and sustainable cannabis industry. This evolving landscape not only presents economic growth opportunities but also addresses historical injustices tied to drug policy enforcement, shaping the future of cannabis legislation in the U.S.

 

WHAT STATES HAVE THE HIGHEST WEED TAXES? READ ON…

MARIJUANA SALES TAX RATES

WHAT STATES HAVE THE HIGHEST MARIJUANA SALES TAXES?



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