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CBD for Treating Hypertension is Off to a Promising Start Says New Clinical Trial

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CBD for hypertension

Clinical Trials Show That CBD Is Promising For Hypertension

 

Hypertension, also known as high blood pressure, is medically defined as having blood pressure levels of 140/90 or more.

 

When left untreated, hypertension can lead to harmful and even fatal complications which include stroke, heart attack, heart failure, kidney disease, metabolic syndrome, dementia, memory problems, and much more. The primary causes of hypertension are lifestyle factors such as being overweight, consuming too much salt, little to no exercises, too much alcohol or caffeine consumption, smoking, and stress. Age is also a factor: those aged 60 and up have a higher risk of having high blood pressure.

 

Pharmaceutical medications are usually the first course of treatment for hypertension, along with lifestyle changes. The treatment will usually depend on the stage of hypertension. Thiazide is a diuretic medication usually recommended alongside beta blockers, which reduce heartbeat and help treat hypertension.

 

However, there are more natural and safer ways to treat hypertension.

 

New studies have found that cannabidiol (CBD) could actually help reduce high blood pressure.

 

In a study out of Croatia, researchers analyzed the impact of CBD against a placebo on 70 participants. They were each given either CBD or a placebo each day for five weeks, and those who consumed CBD were given anywhere from 225mg to 450mg per day. Their findings, which were published in Cannabis and Cannabinoid Research, revealed that oral consumption of CBD was effective in treating ambulatory blood pressure among the individuals who had either mild or moderate stages of hypertension.

 

“The administration of CBD reduced average 24-hour mean, systolic, and diastolic BP [blood pressure] after 2.5 weeks,” said the researchers. “There were no changes in liver enzymes of serious adverse events,” they added.

 

“The results of the present randomized, triple-blind, crossover study indicate that chronic administration of CBD [capsules] reduces ambulatory BP… These findings should be confirmed in larger prospective cohorts to apply them into clinical practice,” concluded the authors.

 

Other Studies Yield Similar Findings

 

In 2017, a study from Oxford, United Kingdom was also conducted to determine if oral CBD affected blood pressure levels among healthy subjects. Researchers out of the University of Nottingham analyzed the impact of one 600mg dose of CBD and compared it to the results of a placebo among 9 male subjects.

 

The results, which were published in the Journal of Clinical Investigation, found that CBD worked to reduce the resting systolic blood pressure as well as stroke volume. CBD reduced BP especially after exercise and when participants were exposed to stress. There were no adverse effects reported by patients during or after the trials.

 

“Our data show that a single dose of CBD reduces resting blood pressure and the blood pressure response to stress, particularly cold stress, and especially in the post-test periods. This may reflect the anxiolytic and analgesic effects of CBD, as well as any potential direct cardiovascular effects….” Wrote the researchers. “Further research is also required to establish whether CBD has any role in the treatment of cardiovascular disorders such as hypertension,” they recommended.

 

Meanwhile, a 2020 study revealed that CBD has the potential to improve the vasodilation in arteries of humans and rat subjects. According to study authors, CBD may do so because of its ability to improve the flow of blood and widen blood vessels.

 

In 2021, an Israeli study examining elderly patients found that cannabis could also improve hypertension. “Cannabis treatment for three months was associated with a reduction in systolic and diastolic blood pressure, as well as heart rate,” wrote the authors. “Current cannabis use was associated with lower resting heart rate” among subjects who are middle-aged.

 

Can You Use CBD for Hypertension?

 

As it stands, there is still a need for more studies to verify the use of CBD for hypertension. However, CBD has been proven to help address the many lifestyle factors that contribute to high blood pressure, such as better sleep, reduced stress and anxiety. When these issues are addressed for many cases of high blood pressure, it can certainly help treat hypertension though the medical community still needs additional clinical trials of CBD for this condition.

 

If you are interested in using CBD for managing high blood pressure, it is critical to speak to your doctor first. More importantly, start getting a regular checkup if you are experiencing the symptoms of hypertension which include: extreme headaches, dizziness, nausea, chest pain, difficulty breathing, and anxiety. Making sure that you are seeing a doctor regularly is key to preventing any condition, including hypertension, from escalating into a severe case.

 

Additionally, make sure that you are going to only use CBD that is sourced from reputable manufacturers. Many unregulated CBD products out there may contain psychoactive THC as well as contaminants. It’s always best to purchase CBD with a certificate of analysis from the manufacturer.

 

Conclusion

 

Hypertension is one of the most common and deadly conditions. Most people don’t even realize they have hypertension until it’s already severe or too late. Pay attention to your lifestyle, get regular checkups, and make the necessary changes that are needed in order to keep your blood pressure levels healthy.


Taking CBD can help you manage stress, lack of sleep, and anxiety – as well as other potential factors that contribute to increased blood pressure. However, until we know more about CBD’s role in reducing blood pressure, it should not be considered as a one-size-fits-all solution for treating hypertension. Speak to a doctor who is knowledgeable about hypertension and CBD – and avoid self-medicating most especially if you are already taking existing medications for the treatment of other conditions.

 

CANNABIS FOR HYPERTENSION, YES OR NO, READ ON…

IS CANNABIS GOOD FOR HYPERTENSION

CANNABIS FOR HYPERTENSION PATIENTS, YES OR NO?



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Is Kratom Addictive? Understanding Dependence, Risks, and Safe Usage

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Is kratom addictive? Discover the potential for dependence on Kratom, the risks involved with its use, and how to approach its consumption responsibly.

From 2011 to 2017, over 1,800 calls to poison centers involved kratom in the U.S. This significant number highlights the concern regarding kratom addiction.

However, without Food and Drug Administration (FDA) oversight, and due to various consumption methods like teas and capsules, there are significant health risks. Safe use of kratom is now in question due to these issues.

Research debates how dependence develops, outlining signs like loss of control and withdrawal symptoms. These signs are seen in regular kratom users. Ironically, some people switch from drugs like heroin to kratom, looking for a legal alternative.

Understanding Kratom: Origins and Prevalence

Kratom comes from the Mitragyna speciosa tree in Southeast Asia. It can act like a stimulant or like opioids, based on how much you take. People use it in different ways, for a small energy boost or stronger effects at higher doses.

The legal status of kratom in the U.S. is complicated and changing. It’s a hot topic because some worry about its misuse. It’s still legal in several states. This shows how different places handle drug rules. The National Institute on Drug Abuse is looking into its medical benefits. But, the FDA hasn’t approved it for medical use yet. The DEA calls it a “drug of concern,” which means policies might change.

  • From 2011 to 2017, poison control centers in the U.S. got over 1,800 reports about kratom. This shows it’s widely used and might pose health risks.

  • Kratom’s main ingredients bind to opioid receptors very strongly, stronger than morphine even. This fact is key to understanding its effects.

  • As more people use kratom, more are reporting serious health problems. These include liver and heart issues, and tough withdrawal symptoms, particularly in those already sick.

The statistics show mounting worries about kratom in the U.S. As its use grows, it’s becoming more important to health policies and laws. What happens next will depend on further research and legal decisions.

Is Kratom Addictive: Investigating the Substance’s Nature

The question of kratom’s addictiveness focuses on how it affects brain receptors and its long-term health implications. The ongoing debate highlights concerns about dependence and the risk of addiction. Scientists are closely looking at these issues.

How Kratom Works in the Brain

Kratom’s main alkaloids, mitragynine and 7-hydroxymitragynine, bind to the brain’s opioid receptors, similar to painkillers and narcotics. This connection suggests a potential risk of dependence. These alkaloids are key to kratom’s pain relief but also point to possible addiction concerns, especially with frequent, high-dose usage.

Patterns and Consequences of Long-term Use

  • Using kratom often, especially in large doses, can increase the risk of dependence and intense withdrawal symptoms, similar to opioid withdrawal.

  • Although some use it for pain or to improve mood, long-term kratom users might see serious health problems, like liver damage and mental health issues.

  • Withdrawal symptoms, including irritability, nausea, and sleep problems, show kratom’s impact on one’s physical and mental health.

Assessment of Addiction Risks

Studies indicate a significant risk of addiction to kratom, especially with high doses or frequent use. Dependence develops as the body gets used to kratom, leading to tolerance and a need for more to feel its effects. Withdrawal symptoms emphasize this risk, as highlighted by health experts.

Physiological Effects: Kratom’s Impact on the Body

There is a lot of debate about the safety and use of kratom. This herbal extract comes from the Mitragyna speciosa plant. It has drawn attention for its possible harmful effects on the body. The FDA has issued many warnings about kratom, raising safety concerns.

  • Kratom Adverse Effects: Kratom users have reported side effects like nausea, vomiting, and confusion. More serious issues include high blood pressure and liver damage. These problems highlight the risks of using kratom.

  • Herbal Extract Safety: Some kratom products contain heavy metals and pathogens. These can cause severe health issues, including death. This shows the importance of safety in herbal products.

  • FDA Warnings and Regulations: The FDA has linked kratom to over 35 deaths and warns against using it. They point out the lack of medical uses and the risk of addiction.

  • Physiological Impact: Kratom’s effects depend on the dose and the user’s body. Yet, it can lead to dangerous outcomes like liver damage and seizures.

  • Safety Concerns from Authorities: Federal agencies like the DEA are worried about kratom’s safety. Although not a controlled substance, monitoring suggests users should be careful.

Kratom might offer temporary relief for some ailments, but it comes with significant risks. The FDA’s warnings should make people think twice. If considering kratom, it’s crucial to talk to a doctor first. Experts stress the need for safety and caution with herbal extracts.

Conclusion

Kratom’s role in health and regulation is complex, with views and research findings widely varied. Some people use kratom for its claimed health benefits, but it’s a hot topic. Experts advise caution and suggest consulting a doctor before using kratom due to the unclear effects.

Clinical studies using scores like SOWS and COWS haven’t confirmed withdrawal symptoms from kratom. This adds to the debate, especially when some users report withdrawal. This makes kratom a controversial subject among different findings and user experiences.

When it comes to treating opioid addiction, kratom can be both helpful and harmful. Some have used it successfully to fight addiction. Yet, some states have banned it. This highlights the need for regulations and consistent product quality. It also raises questions about kratom’s legal status due to mixed actions by authorities.

The situation shows how complex kratom is in the realm of substance use and law. Without clear evidence supporting either its benefits or risks, it poses a challenge. More research is needed to guide regulations and health advice. For now, anyone thinking of using kratom should be careful, seek medical advice, and keep up with laws and health guidelines.

 

WHAT IS KRATOM ANYWAY? READ ON…

WHAT IS KRATOM

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New Rule, December 5: Oregon Cannabis Retailers, Processors and Labor Peace Agreements

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Oregon’s Measure 119 passed last week, as expected. This means that as of December 5th, every OLCC licensed retailer, processor, researcher and testing lab must secure a labor peace agreement before OLCC will approve a new or renewal license application. The labor peace agreement must be with a “bona fide labor organization.”

I previewed M119 back in September, explaining:

Compulsory peace agreements aren’t anything new in cannabis, although it would be something different here in Oregon. California, for example, requires labor peace agreements for many of its cannabis licensees, and has for many years. We had clients struggle with the concept initially, and we saw some fumbled rollouts, but people eventually adjusted.

Measure 119 further provides that retailers and processors would be required to remain neutral, under the peace agreements, when labor organizations communicate with employees about collective bargaining rights “with any licensure or renewal application.”

M119 may be legally problematic

I’m not a First Amendment lawyer, but it’s not clear to me that an Oregon business can be constrained from speaking with employees– regardless of what M119 provides. Oregon’s speech protections are extremely broad, which is why we have a naked bike ride, tons of strip clubs and no campaign finance restrictions.

I’m also not a labor lawyer, but I’m told M119 could hit a snag on the National Labor Relations Act.

I’ve run these concepts by an Oregon First Amendment lawyer and a couple of labor lawyers, and all confirmed to me that M119 has real exposure. I found that feedback interesting, because M119 sponsors would have understood this when they set out signature gathering. Back in September, I wrote:

The United Food and Commercial Workers Local 555 spent a good deal of money to get Measure 119 on the ballot, rounding up some 163,000 signatures when only 117,173 were required. This follows on a stymied effort to get House Bill 3183 passed last year, which would have accomplished the same thing legislatively.

HB 3183 failed after a couple of advisory letters from the State of Oregon, Legislative Counsel Committee (see here and here). Those letters discussed preemption exposure for what is now M119 under the National Labor Relations Act, The Taft Hartley Act, and other federal laws. Oregon Business and Industry, the largest business group in the state, also submitted opposing testimony, highlighting legal exposure.

As to the First Amendment issues, anyone watching this is advised to follow litigation recently brought by Ctrl Alt Destroy, Inc., on a similar requirement in California.

So let’s see how that goes, and let’s see if anyone in the Oregon cannabis space wants to make a run at litigating M119. For now, credit to UFCW Local 555, I guess, for not giving up and for getting this thing on the ballot. And for having some fun by slipping a Rickroll into the voter pamphlet. I’m sure that won a few people over.

The OLCC process

I don’t have any information yet on what OLCC is going to do ahead of the December 5th deadline. It’s worth noting that, in addition to California, other recreational cannabis states including New York, New Jersey, Rhode Island, Connecticut and Delaware all have similar requirements. Most likely, OLCC will put out an FAQ page very soon that looks something like this and licensees will need to upload something or other to CAMP with respect to any post-December 5th application or renewal.

As far as OLCC licensees negotiating these agreements, the best approach would be to speak with experienced labor counsel. Labor law is highly specialized, and negotiating a labor peace agreement with any outfit claiming to be a “bona fide labor organization” is not a typical exercise.

For now, this is just one more thing for licensed cannabis businesses to comply with. Please reach out to us if you have any questions or need a referral.



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The CBD Dog Treat Guide

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CBD dog treats good or bad

As the popularity of CBD (cannabidiol) continues to rise, many pet owners are exploring its potential benefits for their furry companions. CBD is derived from the hemp plant and is known for its therapeutic properties, which may help alleviate anxiety, pain, inflammation, and other health issues in dogs. However, when considering CBD treats for your dog, it’s crucial to understand the ingredients that go into these products. This article will delve into the essential ingredients to look for in CBD treats, their benefits, potential risks, and how to choose the right product for your canine friend.

 

Understanding CBD and Its Benefits for Dogs

 

Before we dive into the ingredients, it’s important to understand what CBD is and how it can benefit dogs. CBD is a non-psychoactive compound found in cannabis plants. Unlike THC (tetrahydrocannabinol), which can produce a “high,” CBD does not have intoxicating effects. Instead, it interacts with the endocannabinoid system (ECS) in both humans and animals, which plays a crucial role in regulating various physiological processes.

 

Potential Benefits of CBD for Dogs

 

  • Anxiety Relief: Many dogs experience anxiety due to various factors such as loud noises, separation from their owners, or changes in their environment. CBD may help reduce anxiety levels by promoting a sense of calm.

 

 

 

 

 

 

Choosing the Right CBD Treats

 

When selecting CBD treats for your dog, it’s essential to look beyond just the CBD content. The overall quality of the treat is equally important. Here are some key ingredients you should be aware of:

 

1. High-Quality CBD Oil

 

The foundation of any good CBD treat is the quality of the CBD oil used. Look for treats that contain:

 

  • Full-Spectrum or Broad-Spectrum CBD: Full-spectrum products contain all cannabinoids found in the hemp plant, including trace amounts of THC (below 0.3% as per legal standards). Broad-spectrum products contain multiple cannabinoids but no THC. Both types can provide an “entourage effect,” enhancing the therapeutic benefits.

 

 

 

2. Natural Ingredients

 

Just like human food, the ingredients in your dog’s treats matter significantly. Look for treats made with natural ingredients rather than artificial additives or preservatives. Here are some beneficial components:

 

Whole grains like oat flour or brown rice flour provide essential nutrients and fiber that support digestive health. They are also a good source of energy for active dogs.

 

Healthy fats are vital for maintaining your dog’s coat and skin health. Ingredients like coconut oil or peanut butter not only enhance flavor but also provide beneficial fatty acids that support overall well-being.

 

Incorporating fruits and vegetables into your dog’s treats can boost their nutritional value:

 

 

 

 

 

To make treats more appealing without resorting to artificial flavors, look for natural flavorings like chicken broth or carob (a chocolate substitute safe for dogs). These ingredients can enhance taste while keeping the treat healthy.

 

3. Functional Ingredients

 

Some treats may include additional functional ingredients designed to address specific health concerns:

 

 

These compounds are often included in joint support treats to help maintain joint health and mobility, especially in older dogs or those with arthritis.

 

 

Probiotics can promote gut health by supporting a healthy balance of bacteria in your dog’s digestive system.

 

 

Certain herbs like chamomile or ginger may offer calming effects or aid digestion. Always ensure these herbs are safe for canine consumption before choosing treats containing them.

 

Ingredients to Avoid

 

While there are many beneficial ingredients to seek out, it’s equally important to know which ones to avoid:

 

1. Artificial Additives

 

Many commercial pet treats contain artificial colors, flavors, and preservatives that can be harmful to your dog’s health. These additives may lead to allergic reactions or other health issues over time.

 

2. High Sugar Content

 

Just like humans, dogs do not need excessive sugar in their diets. Treats high in sugar can lead to obesity and dental problems.

 

3. Low-Quality Fillers

 

Avoid treats with low-quality fillers such as corn syrup or by-products that do not provide any nutritional value.

 

4. THC (Tetrahydrocannabinol)

Always ensure that any CBD product you choose contains less than 0.3% THC to avoid any psychoactive effects on your dog.

 

How to Introduce CBD Treats Safely

 

When introducing any new treat into your dog’s diet—especially one containing CBD—it’s essential to do so gradually:

 

  • Start Small: Begin with a small amount of the treat to see how your dog reacts.

  • Monitor Your Dog: Observe your dog for any adverse reactions such as changes in behavior or gastrointestinal upset.

  • Adjust Dosage as Needed: Depending on your dog’s size and needs, you may need to adjust the dosage over time.

  • Consult Your Veterinarian: Before starting any new supplement regimen, including CBD treats, consult with your veterinarian—especially if your dog has existing health conditions or is taking other medications.

 

Conclusion

 

CBD treats can be a beneficial addition to your dog’s diet when chosen carefully with attention to ingredient quality and safety. By understanding what goes into these treats—such as high-quality CBD oil, natural ingredients, functional additives—and knowing what to avoid, you can make informed decisions that support your dog’s health and well-being.

Always prioritize transparency from manufacturers regarding ingredient sourcing and product testing; this will ensure you’re providing your furry friend with safe and effective options tailored to their needs. With proper research and guidance from a veterinarian, you can confidently explore the potential benefits of CBD treats for your beloved pet while ensuring they enjoy a tasty snack that’s good for them too!

 

CBD OIL FOR DOGS, READ ON…

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