During the double-blind, placebo-controlled study, 100mg of MDMA was paired with 100µg of LSD and given to twenty-four healthy participants (12 men and 12 women between the ages of 25 and 54 years). Despite how much promise researchers were expecting, they were surprised to find that the co administration of MDMA with LSD produced no significant differences compared to taking LSD alone.  

So, why the discrepancy? How come users have been reporting benefits when combining MDMA with other psychedelics for years, but the study found no notable differences? Well, the answer comes down to dosage. The study only investigated 100µg of LSD, which is a relatively low dose. Many people start with 200µg or more to really get the intense kind of trip that produces hallucinations. Low doses of LSD will produce milder trips than higher doses, so it’s possible that if the study used more LSD, the positive effects of the MDMA would have been more evident.   

Researchers noted: “We only tested single dose levels of both LSD and MDMA and co-administration at the same time. LSD at a dose of 100 µg mainly induces high acute positive effects and nominally less anxiety compared with a higher dose of 200 µg. Thus, we cannot exclude the possibility that MDMA may reduce negative mood effects, including anxiety, of higher LSD doses than the dose that was used in the present study.” 

Looks like we can expect to see a follow up study in the future. And it’s worth reiterating that not only does MindMed own the rights to all this research, but they have already obtained a patent to create products that combine LSD and MDMA. I have also seen gummies and capsules that combine psilocybin with MDMA, sold on the black market of course, but they’re great products and it would be interesting to see the two paired in a future research project as well.  

A bit more about MDMA 

MDMA (3,4 methylenedioxymethamphetamine) is known informally as molly or ecstasy, although the former is used to denote pure MDMA, whereas ecstasy is usually cut with other drugs. MDMA appears in crystalline form or powder, which is the purest form of this drug, and ecstasy is the pressed powder tablet version. But to press the powder into a pill, it needs to be mixed with other ingredients, which can also lower production costs and are often harmful to the consumer.  

Like other hallucinogens, MDMA works primarily via interaction with serotonin receptors, although the effects are quite different from other psychedelics like mushrooms and acid. Hallucinations are not typical with MDMA. In my experience, it gave me energy, made me feel really happy and connected, adventurous, it always made my social anxiety melt away, and there’s a sensory aspect to it also, where touching certain things and being touched feels amplified.  

It was created back in 1912 by researchers at Merck Pharmaceutical, but it received little attention, and it wasn’t until the 1970s when the effects of this drug became better understood. American chemist Alexander Shulgin took an interest in MDMA and developed a new way to synthesize it. After testing it with a few fellow psychotherapists, it started being used therapeutically, coupled with different types of therapy treatments. 

Despite being quite effective, MDMA was banned in 1985, and any further treatments or research came to a halt. It wasn’t until the last few years that interest in psychedelics ramped back up, especially for the treatment of PTSD, and numerous areas around the world are working on loosening restrictions on the drug. Last year, Colorado became the first state to legalize MDMA, and it’s been decriminalized in Oregon since 2021. Earlier this year, Australia legalized MDMA along with a handful of other psychedelics for medical use.  

What is a bad trip? 

Bad trip experiences are common among users of psychedelics. In a 2021 survey of 50 Norwegian psychedelic users, nearly every single one of them reported having had “frightening experiences” at least once when using hallucinogens. Aside from the often-discussed psychological side effects, physical symptoms of a bad trip can include irregular heartbeat, nausea, chills, sweating, and anxiety. 

Although scary, many people find ways to make these experiences positive and transformative. It’s not uncommon for bad trips to be viewed as a type of metaphor for an issue the person needs to address in real life. Like how seeing certain things when you look at your own reflection could be an indication that you need to work on your self-esteem.

Many things can cause bad trips, from obvious things like seeing something that is actually scary and overthinking it, to inconspicuous things like catching a glimpse of yourself in the mirror. It’s important to not only engage in practices that will facilitate a good trip, but to practice the type of self-control needed to remind yourself, if you happen to end up feeling negatively about something, that you’re just high and you need to refocus your thoughts and energy.  

Other ways to ensure a positive trip  

Most pyschonauts agree that “set and setting” are key to having a happy and therapeutic psychedelic trip. The general consensus is that it is best to avoid unfamiliar situations, especially if you’re a novice user, and you should do everything possible to construct a relaxing and safe tripping environment BEFORE you start your adventure. That includes the environment itself, AND the people that are sharing it with you.

At best, being around bad company or people that make you uncomfortable can be awkward and unpleasant. At worst, hanging out with the wrong people while tripping can become a literal nightmare complete with terrifying hallucinations. I don’t know about you, but for me, vibes are everything. If I get bad vibes from someone when I’m sober, I’ll feel that negativity tenfold if I’m on psychedelic drugs. To make sure you have a peaceful experience, you absolutely must surround yourself with people you trust and feel completely safe around. 

Psychedelic drugs are also best used on their own, or with other similar drugs at the very least, like cannabis and mushrooms. Mixing with harder drugs and alcohol can be dangerous as they can magnify disorientation and physical symptoms associated with bad trips (nausea, chills, etc.), and some believe that combining these types of substances with entheogens can lead to violent thoughts and hallucinations. 

Also, it’s important to be in a positive headspace before starting your psychedelic journey. If you’re in a bad mood beforehand – feeling anxious, nervous, stressed, scared, or going through some sort of existential crisis – you might want to hold off on the psychedelics. If you’re inexperienced and grappling with dark thoughts, hallucinogens can amplify these and put you in a dangerously negative state of mind. 

When planning your trip, it’s important to keep in mind that certain hallucinogens – mushrooms and LSD, for instance – can produce highs that last for up to 8 hours. Make 100 percent sure that you have enough time to complete your psychedelic journey and come down from it properly without any impending activity or responsibility. If you feel like you’re rushing and have too near of a cutoff time before getting back to reality, you could end up with a veil of dread and anxiety over your experience. 

Final thoughts 

Even though the study didn’t produce the results that researchers were hoping for, people who have experience with these drugs agree that candyflipping can help reduce the risk of experiencing a bad trip, especially in those who are prone to anxiety. The study authors also concluded that at different doses, their experiment may have gone more as expected.

Do you have any experience mixing MDMA with LSD? What about MDMA and other hallucinogens? If so, drop us a line in the comment section and let us know about it. We love to hear the perspectives of our readers!

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This movement brought about an influx of rock music, like the likes of Bob Dylan and Jimi Hendrix. But the youth counterculture also began exploring drugs in a new way. Cannabis was flowing freely and, of course, LSD was a new ointment. What could be a better way to break out of the mold and experience life in a new way than taking acid? 

LSD & Love

At the center of this movement was the use of psychedelic drugs, particularly LSD (lysergic acid diethylamide), which was seen as a means of expanding consciousness and exploring new realms of experience. LSD was first synthesized by Swiss chemist Albert Hofmann in 1938, but it wasn’t until the 1960s that it became widely known and used as a tool for spiritual exploration and personal transformation. Origins writes:

“The CIA experimented with LSD in the 1950s for its potential use in psychological warfare… By the early 1960s, several leading universities had begun to investigate the psychological effects and health benefits of LSD. Most famously, between 1961 and 1963, Harvard professors Dr. Timothy Leary and Dr. Richard Alpert… tested Acid for its therapeutic use.”

As more of the world became aware of the substance, people began to realize its potential for other purposes. The connection between love and LSD was a central theme of the counterculture movement. Many people who experimented with acid reported experiencing profound feelings of love and interconnectedness, and saw the drug as a means of breaking down the barriers that separated individuals from one another and from the natural world.

The use of LSD as a means of exploring love and consciousness was reflected in the art and music of the era, particularly in the psychedelic rock music that emerged during the mid to late 1960s. Bands like The Beatles, The Grateful Dead, and Jimi Hendrix used the substance as a means of expanding their creativity and exploring new musical horizons, while their lyrics often reflected themes of love, peace, and interconnectedness.

LSD Now

Now of course we’re no longer in the 60s, instead we’re existing in the 2020s, which has its own identity. Today, the use of LSD and other psychedelics is being revisited by researchers and medical professionals as a potential tool for treating a variety of mental health conditions, including depression, anxiety, and addiction. Nonetheless, that feeling that makes us feel love and unity with another person is still there. That is why the idea of taking hallucinogens with your loved one can be an incredible experience. Like with any substance, acid needs to be utilized in the right way, to risk any problems arising. So let’s go through the well-required steps of how to have the perfect romantic acid trip. 

The Romantic Acid Trip

Before we can begin any LSD trip, we must first understand how the substance works on the body. It is this that will inform how we go about creating the perfect environment for our romantic acid trip. 

How it Works

LSD is a powerful psychedelic drug that has the ability to profoundly alter perception, mood, and cognition. LSD works by affecting the serotonin system in the brain, which is responsible for regulating mood, appetite, and sleep, among other functions. When LSD is ingested, it binds to serotonin receptors in the brain, particularly the 5-HT2A receptor, which is thought to be the primary target for its effects. This binding leads to an increase in serotonin activity, which results in a range of altered perceptions and sensations.

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The effects of acid can vary widely, depending on the dosage, the individual’s mood and mindset, and the environment in which the drug is taken. The effects of the drug typically last for 6-12 hours, with the peak of the experience occurring between 2-4 hours after ingestion. However, the drug can have longer-lasting effects on mood and cognition, which can persist for several days or even weeks after use. Common effects of LSD include:

1 – Altered Perception

It can cause a profound distortion of the sense of time and space, leading to a feeling of timelessness or a sense of the dissolution of boundaries between oneself and the world.

2 – Hallucinations

it can cause the perception of colours, shapes, and patterns that are not actually present, as well as alterations in sound and music perception.

3 – Heightened Emotions

The substance can lead to intense feelings of joy, love, and interconnectedness, as well as fear, anxiety, and paranoia.

4 – Changes in Thought Patterns

Acid can lead to a loosening of normal cognitive constraints, allowing for more fluid and creative thinking, as well as a tendency towards associative and non-linear thought.

5 – Physiological Effects

LSD can cause a range of physical effects, including dilated pupils, increased heart rate and blood pressure, sweating, and tremors.

The Guide

So we’ve established how acid works on the body, and for how long, now we can start planning our romantic acid trip. Love and acid are both powerful forces but, when combined, they can move to a whole other level. Or, of course, if done incorrectly, they can open a world of despair. But don’t worry, that shouldn’t happen if you follow these steps. 

1 – Research 

In a sense, you’ve already done this part. But it’s always vital to educate yourself about the effects of LSD, potential risks and benefits, and how to minimise harm. Read up on harm reduction techniques and best practices for safe psychedelic use. No one wants to sound like Talk to Frank, but the aim here is to really enhance the benefits of this wonderful substance. It will also give you confidence in your experience. 

2 – Partner

Next thing to do is to ask yourself the ultimate question: is this experience right for my partner and myself? This isn’t to give you doubts, it’s simply to highlight that acid is not for everyone. Worst case scenario you have a slightly unpleasant experience, it’s not the end of the world, but that isn’t always nice to add to the memories of a relationship. Ensure you feel comfortable, familiar, trusting and warmth from your partner before engaging in something as intimate as this. This doesn’t mean you both need to have tried it before, but it means you both need to rely on one another. You most likely won’t have a trip-sitter for this experience, so you’ll need to act as one for each other at different points in the journey. 

3 – Set

The next step is to consider you and your partner’s mindset. This means both as a couple and individually. When taking acid, your subconscious can quite easily become your conscious, so any negative thoughts, worries or concerns you may have can materialise themselves. This can be very therapeutic in one way, but it can also be quite unpleasant. Make sure that you’re not overly angry, sad or stressed before the experience – or at least not in a way that you don’t want to face during the trip. As said, many people use LSD to face and tackle these thoughts head on and it can work a treat. But this doesn’t mean that the trip won’t be tough. This is the same when thinking about your shared mindset. Ideally taking acid should boost your love between each other, but it can also help resolve issues too. But, again, that will only work if both of you are willing. 

4 – Setting

Then there’s the setting: where this is all taking place. For a romantic trip you’re going to want somewhere that oozes love and warmth for you both. This may be a beach somewhere, it could be a forest, it could simply be your living room. Don’t judge yourself – wherever you feel the most comfortable and safe with your partner is the place for you. Ambience is also crucial – choose the right music, the right candles or lighting state and even some incense.

All of your senses will be heightened. Also make sure that you have easy access to food, water and even a toilet and a bath, you never know when you might need them. Whilst many people love being amongst nature when on a trip, others prefer the comfort of a sofa and a bed. Don’t judge yourselves, simply find the place that you both feel snug. 

5 – Dosage

If you’re somewhat new to tripping – or you’ve only done it once or twice – start with a low dose. This allows you to test your sensitivity to the drug and assess its effects on your body and mind. Not only that, but it gives you both the time to edge yourselves into it and not completely lose yourself. Remember that LSD is a potent substance and its effects can vary widely from person to person. If you’re a bunch of psychonauts then, of course, take as much as you feel works for you. 

6 – Have Fun

Last but by no means least, enjoy yourself! Love and acid is a powerful combination and it can be made even more exciting by having things to do during a romantic acid trip. Play games, watch movies, run around, make love, maybe even discuss things on your mind – whatever works for you. This is a no judgement zone and maintaining that is crucial. If you both want to sit around wearing no clothes and pretending to be pirates then so be it. When the trip comes to an end, and you’re lying in each other’s arms, you should have a sense that you’re closer than you were before the trip started. That is the beauty of LSD and love.

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