Cannabis

Data Suggests The Perfect CBD To THC Ratio

Published

1 year ago

August 7, 2023

admin

Researchers from the University of Colorado’s Anschutz Medical Campus analyzed the impact of cannabis flowers with almost equal ratios of THC and CBD, and its effects on subjects. The data suggests the perfect CBD to THC ratio

The study, published in the journal Addiction Biology, examined subjects who were tasked to smoke cannabis flower with various ratios, which were randomly assigned. These included 24% THC and 1% CBD, 23% CBD and 1% THC, as well as flowers that had almost equal ratios of each, 10% THC and 9% CBD. After an hour, the researchers measured their effects.

Will Congress Boost Hemp Total THC Limit To 1%? — Photo by anankkml/Getty Images

They found that the patients who smoked the THC dominant cannabis and those who smoked nearly equal ratios and those who smoked the flowers with almost equal ratios experienced similar positive benefits. The difference was that the participants who consumed samples with nearly equal ratios reported less negative side effects including paranoia and anxiety.

“This is one of the first studies to examine the differential effects of various THC and CBD ratios using cannabis flower chemovars that are widely available in state-regulated markets. The present findings suggest that CBD may be associated with an overall reduction of THC exposure and may mitigate the negative psychotomimetic effects of THC without diminishing the effects of THC that individuals report liking,” they write.

“The results of the present study suggest that participants using the THC+CBD chemovar had significantly lower plasma THC levels and reported less paranoia and anxiety as compared to participants using the THC dominant chemovar. Importantly, despite these differences, participants in both the THC+CBD and THC conditions reported similar positive subjective effects… The harm reduction implication of these findings is that cannabis chemovars containing CBD may result in less overall exposure to THC and subsequently less potential for harm, particularly with respect to the psychotomimetic effects of THC,” they concluded.

Why Ratio Matters

CBD and THC are the two primary cannabinoids in the cannabis plant. They each have their own properties; THC is the psychoactive compound that is responsible for making you feel high. The more THC a flower or product contains, the higher you will feel. But aside from just getting you high, THC is widely used for its medicinal properties such as its ability to induce appetite, treat insomnia, stop nausea, and provide relief from pain. However, the right dose is essential because too much THC can make people feel paranoid and anxious. On the other hand, CBD is non-psychoactive and is used for relaxation, insomnia, anxiety, pain, and much more.

When the two are combined in varying ratios, they enhance each other’s beneficial properties synergistically in what is known as the “entourage effect”. Aside from that, all of us have a different biological makeup which is why how you react to CBD may be different from how your friend reacts to CBD, even if you both took exactly the same dose.

It has been recognized by scientists that the ideal dose for most people who want to achieve the most therapeutic benefits is an equal ratio of each, or 1:1 THC CBD. This ratio can help you stay productive without feeling too high since CBD counteracts the highs of THC, while also offering a wide range of health benefits including pain management, anxiety reduction, and better sleep among others.

Common Ratios

When shopping around for cannabis products, those that use a combination of both cannabinoids present various ratios. Here are the most common ratios:

0:1 CBD THC: With no CBD in the product, you will be able to feel the highs of THC which many find to be uplifting and euphoric, while reducing stress. If you are one of those people who are sensitive to THC or have a low tolerance, you may be prone to anxiety and paranoia. However, many people prefer it because it provides relief from pain and inflammation while improving energy and mood.

Delta-10 THC: Is It The Future Of Cannabis? — Photo by GRAS GRÜN via Unsplash

1:0 CBD THC: A product that has no THC will not make you feel any kind of high. People who enjoy the relaxation brought about by CBD will appreciate these types of products as they can mildly sedate while still improving your mood and helping to reduce anxiety and panic attacks.

1:1 CBD THC: For people who aren’t familiar with CBD and THC, this is the recommended ratio to start with. You will be able to experience the best of both worlds, but also the presence of CBD will negate getting too high from the THC. In addition, you will be able to stay functional and productive.

1:9 or more: These are usually high-THC products, which means that you will likely experience the characteristics that are typically associated with THC. These may be beneficial for people who are suffering from severe pain, nausea, migraines, lack of appetite due to chemotherapy or radiation, and more. Just keep in mind that it also means you will get a high.

Aside from these, you will also encounter other ratios in the market such as 2:1, 3:1, or 4:1 as well as 25: 1 and others. If you aren’t sure where to start, remember that the more CBD it contains, the less THC psychoactivity you will experience. If you don’t want to get high, always opt for a product that has a higher CBD content or an equal ratio.

Talk to a budtender at your nearest dispensary to learn more about recommendations based on your personal needs. These ratios are available in many cannabis products from oils to tinctures, edibles, and so much more.

Source link

Cannabis

Can Microdosing Help Manage Holiday Family Anxiety

Published

11 hours ago

November 22, 2024

admin

The holidays can be festive, fun and heartwarming – but for some, there is too much family drama….microdosing could make it better.

Carols, gifts, parties, festive meals with favorite foods are all part of hte holiday season. But even in the best circumstances, there could be stress. Some 89% say concerns around money, missing loved ones and anticipating family conflict cause them stress at this time of year. But roughly have say it is moderate and may not be any more than the rest of the year. While family tend to provide a positive effect, if you look at Reddit, there are are plenty of causes of drama during hte holiday at gatherings. For those who are experiencing some level of stress, can mircodosing help manage holiday family anxiety? It could be a better solution than a half of a bottle of booze.

Microdosing marijuana can be an effective way to manage holiday anxiety, offering a subtle yet impactful approach to stress relief during the festive season. By consuming small amounts of cannabis, typically between 1 to 2.5 milligrams of THC, individuals can experience the therapeutic benefits without feeling overly intoxicated.

Microdosing cannabis can provide several advantages for those dealing with holiday-related stress. Low doses of THC can activate the endocannabinoid system, potentially leading to decreased stress levels without causing an overwhelming high. This can be particularly helpful during family gatherings or social events that may trigger anxiety. It may alleviate the effects of social anxiety, allowing individuals to feel more relaxed and confident in social situations. This can be especially beneficial during holiday parties or family reunions.

Small amounts of cannabis can boost mood and social confidence, contributing to a more relaxed and enjoyable holiday experience. Another benefit is may induce deep, natural sleep patterns without excessive grogginess, helping to combat short term holiday-related insomnia.

To microdose marijuana effectively for holiday anxiety, consider the following tips:

Start Low: Begin with a dose of 1 to 2.5 milligrams of THC and maintain this dosage for at least three days. If you’re new to cannabis, begin with an even lower dose and gradually work your way up.
Gradual Increase: If needed, slowly increase the dosage in 1 mg increments until you begin to feel the desired effects.
Consistency: Once you find an effective dose, stick with it for at least four days to assess its impact.
Choose the Right Product: CBD-dominant strains or products with balanced THC:CBD ratios may be more suitable for anxiety relief.
Consider Terpenes: Look for cannabis products containing terpenes like limonene, pinene, and beta-caryophyllene, which have stress-relieving properties
Timing is Key: Plan your microdose schedule around holiday events or stressful situations to maximize its effectiveness.

While microdosing can be beneficial, there are some general precautions. Consider potential interactions with alcohol or other medications you may be taking during the holidays. If you are some medications, it is important to talk to a health professional. And remember everyone reacts differently to cannabis, so what works for others may not work for you.

By incorporating microdosing into your holiday stress management strategy, you may find yourself better equipped to handle the pressures and anxieties that often accompany the festive season. This approach allows you to potentially benefit from the calming effects of cannabis while maintaining clarity and function during holiday activities and gatherings.

Source link

AARP

Lawsuit Says DEA Acting In Bad Faith Over Marijuana

Published

13 hours ago

November 21, 2024

admin

It has been clear the DEA is slow to change for cannabis…but have they done something shady?

It has been clear Anne Milgram, the head of the Drug Enforcement Agency (DEA), is no fan of cannabis and is not pleased with the push to reschedule. Now a lawsuit says DEA acting in bad faith over marijuana. David Heldreth, CEO of psychedelic research firm Panacea Plant Sciences, claims the DEA’s recent actions violate federal law and constitutional principles. Filed in filed in the U.S. District Court for Western Washington, names the Department of Justice, Attorney General Merrick Garland, DEA Administrator Anne Milgram and DEA Judge John J. Mulrooney II as defendants. So what’s going on?

It is no secret, the current President isn’t a fan of cannabis and waited 3 years to fulfill his 2020 promise to help the industry. The timing allowed his administration to pass the decision to the next president. DEA head Milgram has been reluctant about the issue despite recommendation from Health and Human Services, the Food and Drug Administration, the American Medical Association and the American College of Physicians. All of those agencies recommended the change due to clear research showing the medical benefits of cannabis, especially with cancer, chronic pain, PTSD, and inflammation. For the DEA not to follow goes against all precedent.

Heldreth’s alleges legal violations in the DEA’s rulemaking process. He contends the agency failed to consult Native American tribes despite ignificant impact rescheduling marijuana would have on tribal law enforcement and health services. Additionally, Heldreth challenges the constitutionality of the DEA’s Administrative Law Judges, arguing their appointment by the DEA administrator violates Article II of the U.S. Constitution.

Heldreth is the latest in complaints as a Veteran’s organization is claiming they have been blocked from the hearings, despite the Veteran’s administration working with the industry to figure out a pathway for veterans with PTSD.

Milgam has been obstructive to the late in term admisntration’s move, working to stop the process. After the announcement to reschedule, Anne Milgram made the unusual request of a “off the record/no notes meeting” to top deputies summoned in March for what she called the “Marijuana Meeting”. What followed with a request to the Department of Justice (DOJ) which would slow the process if not stop it. The DOJ pushed back on the request.

With millions of patients using medical marijuana, including veterans, plus thousands of mom and pop businesses, Milgram’s actions are murky. Science has changed the direction and it seems the DEA is the only agency standing against the movement.

Source link

blood

Can Marijuana Consumers Donate Needed Blood

Published

2 days ago

November 20, 2024

admin

If you drink alcohol, you can drink, but it has to be out of your body’s system. it is recommended you not have booze 24 hours before donating. Like alcohol, you can donate blood, but you have to let the marijuana move out of your system. Potential donors cannot give if cannabis use impairs their memory or comprehension. The Red Cross does not test blood donations for the presence of tetrahydrocannabinol, or THC, the principle psychoactive component of the cannabis plant. But you should wait 24 hours from the last time you are high.

Donating blood is easy. You go to the nearest location, sign in, show ID, and read some information. You’ll answer questions online or in person, and receive a health check.

The acutional process is easy, a sterile needle is inserted into a vein in your arm, and blood is drawn into a bag. The donation usually takes 8–10 minutes and feels like a quick pinch. Afterwards they providea snack and drink and 10–15 minutes to recovery before resuming your day.

Source link