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Does A Medical Setting Affect Psychedelic Treatment?

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As psychedelics gain acceptance quickly, laws in different states are changing to accommodate their possession and use. So far though, the only states to legalize have done so with an allowance for use in a medical/supervised setting. How useful is this medical setting to psychedelic treatment, and can it get in the way?

What is a medical setting?

When it comes to using psychedelics, there are no specific rules for what will lead to a good trip, and what will bring on a bad one. Though this can do with individual reaction to the drug, it also has to do with outside factors that can impact our individual reaction. We’re often told ‘set and setting’ play a big role in a trip going smoothly, and this can encompass different factors.

‘Set and setting’ refers to the place you’re having the experience, and the environment around. You could be in the woods, or on the beach, or at a dance club, or alone with your partner. The environment around might include the other people you’re interacting with, how crowded it is, if other people are also having the same experience, if you’re doing something organized or on your own, lighting and sound, and even the weather around you.

A medical setting is another type of setting, but until recently, it wasn’t associated with taking a psychedelic drug, or hallucinogen of any kind. However, as research amps up, and legalizations roll in, that idea of a medical, or supervised setting, becomes that much more important, as it’s the only setting legally available to use the compounds in question.


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A medical setting is not one specific thing. Also referred to as a ‘healthcare setting,’ and expanding into ‘supervised setting’, this term encompasses: “acute care hospitals, urgent care centers, rehabilitation centers, nursing homes and other long-term care facilities, specialized outpatient services (e.g., hemodialysis, dentistry, podiatry, chemotherapy, endoscopy, and pain management clinics), and outpatient surgery centers. In addition, some healthcare services are provided in private offices or homes.”

The last one is important, because it reminds us that our own home can be a medical setting under the right conditions; which is the medical setting most people should automatically be the most comfortable with. And when it comes to ketamine, it is offered by many clinics as an at-home treatment which both cuts costs, as well as gets away from the medical setting that not everyone is comfortable with.

In reality, both current psychedelics legalizations aren’t for medical use, and the legislation uses the term ‘service center’ instead. Considering it’s a formal setting, with a person watching over, it represents essentially the same thing. Perhaps its not so much about a ‘medical setting’ as a ‘controlled setting’, but the same idea of how it can affect a trip, applies. It seems Colorado might understand this a bit better, allowing for treatment outside of authorized service centers, but what this actually entails is not entirely clear.

Does being in a medical setting affect a psychedelic trip?

There isn’t one specific answer to this, and not everyone has the same requirements. For some people, the experience won’t differ greatly depending on set and setting, and for some people it will make all the difference. For everyone in between, well its hard to say. Plenty of trials for psychedelic medications have gone on at this point, and for those, we only get the results of the medical setting. Is it possible that results might have differed if the trials were run in a more familiar, or chosen, surrounding?

I came across an interesting statement when researching the Salvia divinorum plant, and the different ways that users describe the experience. Found in a Wired magazine article, and written by Daniel Oberhaus in 2020, the article details the writer’s own experience as a part of a research study into how the compound salvinorin A affects the brain during use. The trial took place at Johns Hopkins University in Baltimore, a research hospital, and involved being hooked up to an fMRI machine.

Per Oberhaus, “I had just inhaled an unspecified dose of the pure crystalline substance from a hose attached to what one of the researchers characterized as an ‘FDA-approved crack pipe.’” He continued, “My psychedelic experience in the fMRI machine was markedly less otherworldly. On the second round, I saw some colorful pinwheels and felt as though my body had merged with the machine. But I didn’t enter another dimension or dissolve into pure being”.

How much does set and setting affect psychedelic experience
How much does set and setting affect psychedelic experience

What are his thoughts as to why his experience in the trial differed from his experience using salvia illicitly, outside of a hospital setting? “This may have been because I received a lower dose. Or it may have been because it’s harder to give in to the experience when you’re inside a giant machine making a racket while it soaks your head in a powerful magnetic field.”

Being in an fMRI machine is much more extreme than simply sitting in a doctor’s office. But consider that most people who do ketamine illicitly, do it by snorting the drug; and one of the more common medical techniques is hooking someone up to an IV. The idea still resonates. Neither being stuck in a tube, or hooked up to an IV in a doctor’s office will likely be the chosen set and setting for many people. And no matter how comfortable you try to make a doctor’s office, it might still have the ability to change the experience.

Tack onto that the cost of the treatments, and this could make patients apprehensive about the outcome of their treatment, which could also affect experience. When getting a service is so expensive, you can’t mess around with it, and for people scraping to make this happen, there’s increased pressure to ‘get it right’. A less controlled environment could pose cost reduction ability, and make users more comfortable about what they’re spending.

My own experience in a medical setting for psychedelic treatment

On this particular topic, I can throw in my own opinion, as I did receive ketamine treatments in a doctor’s office, as well as having previously used the drug on my own illicitly. I’ll take a second to remind that ketamine is a dissociative hallucinogen, not a psychedelic. It is used for therapy in a similar way to psychedelics, and is currently the only legal way to get such treatment, as neither state thus far that legalized any form of a hallucinogen, started services yet.

I ended up in the office of a psychiatrist in Guadalajara, Mexico, which is one of the only places in Mexico that provides ketamine treatments. Most of the doctor’s business is for pain. I went because of sleep issues, which falls under psychiatric. There are very few people who do this there. As such, the procedure isn’t established like it is in American facilities; and from the beginning I was left to feel like not everything was being covered. I made the most of the experience, but looking back I can see how badly it went.

I was hooked up to an IV, and I sat in a comfortable enough place, but was it really? It was a kind of cold office, with no blanket offered, dim lighting, and no window. I was on a couch facing a desk, with very little around me. Sure, it was okay, but I wasn’t super comfortable. Nor did I like having an IV hooked up to me, or seeing the blood squirt out when they had a hard time getting my vein (both times!) I left with blood stains on my pants the second time. I didn’t enjoy the actual drug experience at all; it left me feeling queasy, shaky, and incredibly anxious. And while this could represent my own personal reaction to ketamine, there’s a problem here…

IV ketamine treatment in medical setting
IV ketamine treatment in medical setting

I did ketamine plenty illicitly. I used to do lines with an ex-boyfriend frequently enough to have a great idea how the drug affects me. I liked it back then. Not my favorite of all drug experiences, but very interesting. I used to feel like I was floating, disconnected, like my brain was pulling in different directions. But not bad. And at no point with the anxiety and discomfort I suffered in the doctor’s office. An anxiety so bad the doctor did not push me for another appointment (or even contact me again for follow-up…I would never got back to that provider).

The experiences were so wildly different, that it makes me wonder how much of my negative experience in the medical setting with the psychedelic-like drug, was related to being in that setting, rather than a place I am more comfortable with. My experience gives a huge amount of credence to the idea of at-home ketamine therapy, and the ability to do the treatment in the comfort and privacy of your chosen location. Perhaps under other circumstances, I would not have been a non-responder.

Conclusion

It’s not for me to say what works for other people. But when it comes to expensive treatments, or ‘services’, how many people want to pay out for something that isn’t what they’re looking for? And how much do we damage our own understanding of the usefulness of something, when the controls for use are so extreme? It’s not like these drugs are used illicitly in a medical setting; and people turn out just fine when using a psychedelic on their own, or in a less restrictive way. Maybe that’s something that should be remembered.

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Three Wise Men Give Marijuana Strain Gift Suggestions

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It has become a popular gift with over 20% of the population putting it under the train. So we asked 3 wise man what to give (or consume) during the season.

The holiday season is a special time of year with a combination of Christmas, Hannakuh, and more are the modern hoildays descended from pagan holidays. Food, celebrations, gifts and a hint of something magical are all part of the holidays.  With Christmas, the three wise men bring gifts to the baby Jesus being steered by a star.  As we head into the last part of the season, why not think of the perfect gift to give or for yourself.  We have three wise men give marijuana strain gift suggestions to share with our readers.

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Terran Cooper, one of the rising stars of the industry and a part of the firm Falcon Rappaport & Berman who works in the cannabis industry.  New York based, he says while there are several great strains, he has two to share for the holiday season.

One of my favorite day time strains, Pineapple Express has skyrocketed in popularity following the 2008 film by the same name. This strain is one of the more energetic strains that I’ve come across, allowing for a nice balance between productivity and relaxation this holiday season. Its joyful and uplifting effects may pair nicely with last minute holiday tasks in addition to any festivities. Though infrequent consumers beware – its relatively high THC content means that a little can go a long way.

Beautifully wrapped Christmas gifts under a festive tree with glowing lights.

Andrew Laub, managing partner of Keneh Ventures and CEO of Cannabition, is a leader in the industry and shared his favorites. Golden Goat is my secret to finding joy in any moment, especially during the holiday season. Its tropical, citrusy flavor is bright and uplifting, just like its effects. I love how it gives me an energized, creative boost without feeling overwhelming, making it perfect for everything from decorating the house to hosting friends. It’s my reminder to savor the fun and chaos of the holidays.

Granddaddy Purple is like my personal escape when the holiday rush gets overwhelming. I love its rich, grape-like flavor and how it helps me unwind at the end of a busy day. Whether I’m binge-watching holiday movies or enjoying quiet time by the fireplace, this strain makes everything feel a little cozier and more magical.

Sour Diesel is my motivation when there’s too much to do and not enough time. Its energizing, citrusy aroma wakes me up, and its focus-boosting effects help me tackle long to-do lists with ease. I love using it to power through holiday prep, whether I’m wrapping gifts, planning meals, or brainstorming creative ways to make the season special.

RELATED: Holiday Hangover? Here’s How To Stop It Before It Strikes

Online cannabis influencer Miguel a.k.a Miggy420 (@miggy420) believes consumption of cannabis is a personal experience with everyone being different. He sees the endocannabinoid system as unique as snowflakes in winter. Some smoke to wash away ills, others to wash away the ills of society. He shared his two favorites.

Vin Diesel Diesel is a sativa grown by Dewey’s Cultivars. Her beauty matches her taste with gassy hits reminiscent of early 2000 diesel strains I would buy in the traditional market. These growers come with a biochemical background and it shows with this plant, pure bliss – and this is coming from someone who prefers indicas.

If you’re looking for something post family events i.e you just realized the debt you incurred for the little ones or you’re just happy your conspiracy Uncle is gone, I recommend Gelato Cake by Agro Couture. This indica dominant hybrid will have your mind drifting away and able to focus on what it is you really wanted to do, hot box your bedroom and binge watch YouTube.

Enjoy these suggestions and may everyone have a great holiday season.

 



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The Best Cocktails To Make You Feel Festive

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Lean into the joy of the holiday season with this merry cocktails – delight your taste buds and favorite people!

According to TikTok, it s the most wonderful, stressful, fun, boozy time of year. So why not lean into the season and make merry with something fun. Here are the best cocktails to make you feel festive, no matter what the situation. Plus, these are drinks you can make quickly with minimum effort and maximum fun. Pour one of these concoctions and have a moment of peace or share them with the one you like, love or tolerate at work. Sip, savor and bring a little ho ho ho into the moment.

RELATED: Beer Sales Flatten Thanks To Marijuana

Christmas Old Fashioned

Here is a way to settle into a cozy beverage which will warm your body and soul. Bourbon has been part of the holidays for generations…and you can make this a new tradition.

Ingredients

  • 2 oz bourbon
  • 1/2 oz simple syrup
  • 2 dashes bitters
  • 2 dashes orange juice
  • Garnish: cinnamon stick and orange peel

Create

  • Combine ingredients in a mixing glass and add ice

  • Stir for 20 seconds

  • Strain into a rocks glass with ice

  • Garnish with orange peel and a cinnamon stick

White Bishop

Easy, Tasty Egg Nog

You either you love it or hate it, but Egg Nog is a holiday staple. This recipe makes it lighter, tasty and a wee dangerous since it is so good. It bring a whole new take on a staid drink.

Ingredients

  • 2 oz store bought egg nog
  • 1 oz milk (2% is the best)
  • small splash vanilla
  • 1 oz Licor 43

Create

  1. Combine egg nog, milk and vanilla
  2. Stir until well mixed
  3. Add Licor 43 and stir again
  4. Pour into a fun glass and enjoy

White Bishop

The Bishop’s Wife is a great holiday movie filled with the Christmas spirit and some never ending booze. This drink is an embraces the fun, warmth, snow, and spirit of the evening.  Perfect as a dessert drink, a morning treat or just to lift your holiday mood.

  • 2 oz vanilla vodka
  • 1 oz heavy cream
  • 1 oz Frangelico or Licor 43
  • Small splash of vanilla

Create

  1. Combine all ingredients in shaker with ice
  2. Shake for 20 seconds
  3. Strain into a martini glass

RELATED: Rainy Weather Cocktails

Poinsettia Champagne Cocktail

Nothing says celebration like bubbles. Whether you use champagne or prosecco, this is bound to bring a smile to your face. And the poinsettia is Christmas tradition since

Ingredients

  • 1/2 oz orange liqueur
  • 3 oz cranberry juice
  • 3 oz of champagne or prosecco
  • Garnish with fresh cranberries

Create

  1. Pour orange liqueur and cranberry juice into a chilled champagne flute
  2. Stir well
  3. Top with champagne
  4. Garnish with a few fresh cranberries

Have a great holiday season!



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The Best Tips If You Are Giving Marijuana As A Gift

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Roughly 25% of people are planning to give cannabis as a holiday gift….here are some practical suggestions to make it a success.

Last year was a watershed year for Santa with 1 in 4 planning to add cannabis into their gift giving, the trend is only going up in 2024. Since the plant has become mainstream (except for a few in DC), it is to be found under the tree, next to the menorah and during festive gatherings. Gen Z and Millennials are leading the trend with 78% (vs. 56% of Gen X and Boomers) in planning to include cannabis in their holiday plans. But you you want to do it right, here are the best tips if you are giving marijuana as a gift.

RELATED: Science Says Medical Marijuana Improves Quality Of Life

While giving alcohol is a long tradition, giving cannabis is does have some variances.  To start, so far most can’t grab it out of personal stock or fish it out of Christmas gifts already given for the year. While Costco, groceries stores and Total Wine are the booze top sellers, it can be also purchased in bodegas, gas stations and other locations. Cannabis still has to be purchased at specialized dispensaries.

marijuana dispensary
Photo by smodj/Getty Images

First, plan ahead when you shop. The good news is most dispensaries keep hours similar to a grocery store – open by 9 am and closing around or after 10 pm. This makes dashing in for a last minute gift or squeezing it in during the day easy. Remember to bring cash, have a plan and chill out.

The good news isyou can’t seem to be “cheap” giving weed. Most edibles are in a small price range, whereas wine bought at a grocery stores can go for $6-$100.  And the quality of the wine can vary greatly. Most edibles, including gummies, are within the same price point and potency while caring on quality.  Wana Brands, one of the nation’s leading gummy makers, hits the mid spot on price.  Also, unless you are doing a hefty gift basket, you are can give one or two items as a trail.

Never overestimate someone’s usage. Think about the recipient’s experience level and preferences when selecting cannabis gifts. For most, consider starting with low-dose or CBD-dominant products. Gummies, vapes, oil, or gift cards are all popular choices.  Also, ask the budtender what the best sellers for mid level consumers.

RELATED: The Most Popular Marijuana Flavors

If you are in the less than 50% of the population where legal cannabis is available, consider hemp beverages. It can provide a quick, similar high but is legal.  In Texas, they are huge sellers and can be found in some Total Wines, local convenience stores and other locations.

Lastly, have a hint of discretion, it might not be the best public secret Santa gift, but gummies can be a fun White Elephant!



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