Cannabis News
Not Afraid to Die – How Psychedelics Can Help Terminal Patients at the End of Life Stage
How Psychedelics Can Help Patients At The End Stage Of Life
Psychedelic drugs have long been associated with fun and recreation.
Tripping out to magic mushrooms, getting high on LSD or ketamine, spending hours in ecstasy thanks to MDMA.. these are experiences that can only be associated with positive and fun times, right? Of course! But that’s not all. While we also know that psychedelics can bring about spiritual and religious experiences, recent research and anecdotes have proven that psychedelics may also be an essential tool for patients of terminal illness – as they face the last few months or years of their lives.
It turns out that psychedelics actually have emotional as well as psychological benefits for terminally ill patients. Anxiety about their final day, or general death anxiety, is just one of the most common yet debilitating concerns that the terminally ill have to contend with. They also face a wide range of mental and emotional issues that can make daily life difficult, especially as their illness progresses.
Other issues that patients at the end stage of life experience include depression, suicidal ideation, fear, loss, grief, anger, frustration, regret, isolation, loneliness, and denial. The right spiritual and psychological care can help them move towards a space of peace and acceptance, instead, which are much more positive and helpful emotions. Using cannabis in hospice care is on the ballot in some states as well. How can psychedelics help with that?
Psychedelics Helps Reduce Severe Anxiety Among Terminal Patients
In 2016, Anthony Bossis co-authored a groundbreaking study of 29 cancer patients. During the study, he and his team discovered that just one dose of psilocybin greatly reduced anxiety and depression, which also contributed to a reduction in the hopelessness and demoralization caused by cancer among the patients. In addition, psilocybin “improved spiritual wellbeing, and increased quality of life,” they said.
In a Washington Post article on psychedelics and terminal illness, Bossis explains that exposure to psychedelics can help terminally ill patients feel a greater connection to something other than their physical selves. “After this experience, people often say, ‘I realized I’m not just my cancer. I’m not just this body. I’m something more enduring,’ he said.
There is likely a strong correlation between the spiritual experience brought about by psychedelics and the reduction of anxiety.
Psychedelics Reduces Fear Of Death
In 2022, Johns Hopkins Medicine released the results of a poll of over 3,000 adults which helped them compare near-death experiences with psychedelic drugs. The participants were divided into several groups: those who had non-drug related near death experiences, while the rest had psychedelic experiences with either LSD, ayahuasca, psilocybin, or DMT.
The researchers found interesting results, particularly that there were significant similarities among people’s attitudes towards death. Specifically, they found that just one treatment with psilocybin resulted in a sustained reduction in depression and anxiety among patients with terminal cancer. They found that around 90% of the participants, both who had near death experiences and psychedelic experiences, reported a decrease in death anxiety when they considered how their perceptions changed afterwards.
Meanwhile, many participants belonging to both categories said that their experience was among the top most significant and meaningful in their lives. They also admitted to having strong to moderate positive changes that affected their well-being and life purpose afterwards.
Psychedelics Reduces Depression Among Cancer Patients
In 2021, researchers at the Aquilino Cancer Center enrolled 30 cancer patients with major depressive disorder into a feasibility study. They were given a 25mg dose containing synthetic psilocybin called COMP360; each of them were also provided with one-on-one support with therapists over the course of their 6-8 hour treatment.
What followed was 8 weeks of monitoring to observe any changes in symptoms of depression. Half of the study’s participants were already taking antidepressants for their depression, and others were being treated for cancer. However, most of the patients didn’t have any previous experience with psychedelics. Using the Montgomery-Asberg Depression Rating Scale (MADRS), participants were asked to rate their depression symptoms through a survey.
While all 30 patients started with a 25.9 MADRS score, which reveals moderate depression, the period following psilocybin therapy reduced the score by 19.1 on average. “Cancer can ravage a patient’s entire life. In addition to attacking the body, cancer also impacts a patient’s mental and emotional wellbeing. It’s time we practice whole-person healing in oncology, which means meeting all the needs of our patients, both physical and psychological,” said Paul Thiambi, MD, one of the researchers in the trial.
Current Challenges Among Clinical Trials
Studying the benefits of psychedelic drugs for the terminally ill is still at its infancy. While the medical industry has surely made strides in this aspect, there’s also still a lot that we don’t know. Researchers face several obstacles that prevent them from making solid claims at this point, especially the fact that it’s difficult to ensure both participants and researchers alike have no clue they’re using the real thing or a placebo.
Furthermore, how psilocybin works in the human body is still largely mysterious. While we can certainly say that many terminally ill participants surely report less anxiety and depression after taking psychedelics, we aren’t sure how it works to cause that. There are some studies that point to stronger mystical or spiritual experiences, even among patients who weren’t actually religious, after taking psilocybin or other psychedelic drugs.
On top of that, there’s also the ethics and legalities that surround it. In most states, psychedelics resides in a legal gray area. Even if patients themselves want to access psychedelics, medical institutions and the law can make it challenging because of the ethical considerations of doing so.
Conclusion
No matter which way you look at it, psychedelics as a tool for terminally ill patients is indeed promising. Everyone wants to meet their final days with as much grace as possible.
Thanks to the promise of psychedelics, we may be looking at a big shift in how traditional end-of-life care is approached. Terminally ill patients don’t have to go living their last few months under psychological and emotional distress; a small amount of psychedelic treatments could go a long way. One thing’s for sure: use must be properly managed in order to maximize the drug’s benefits and safety.
CANANBIS OR PSYCHEDELICS FOR END OF LIFE, READ ON..
“How Long Does One Puff of Weed Stay in Your System?”… This topic can be difficult to answer since it is dependent on elements such as the size of the hit and what constitutes a “one hit.” If you take a large bong pull then cough, it might linger in your system for 5-7 days. A moderate dose from a joint can last 3-5 days, whereas a few hits from a vaporizer may last 1-3 days.
The length of time that marijuana stays in the body varies based on a number of factors, including metabolism, THC levels, frequency of use, and hydration.
Delta-9-tetrahydrocannabinol, or THC, is the primary psychoactive component of cannabis. THC and its metabolites, which remain in your body long after the effects have subsided, are detected by drug tests.
Since these metabolites are fat-soluble, they cling to bodily fat molecules. They could thus take a while to fully pass through your system, particularly if your body fat percentage is higher.
THC is absorbed by tissues and organs (including the brain, heart, and fat) and converted by the liver into chemicals such as 11-hydroxy-THC and carboxy-THC. Cannabis is eliminated in feces at a rate of around 65%, while urine accounts for 20%. The leftover amount might be kept within the body.
THC deposited in bodily tissues ultimately re-enters the circulation and is processed by the liver. For frequent users, THC accumulates in fatty tissues quicker than it can be removed, thus it may be detectable in drug tests for days or weeks following consumption.
The detection time varies according to the amount and frequency of cannabis usage. Higher dosages and regular usage result in longer detection times.
The type of drug test also affects detection windows. Blood and saliva tests typically detect cannabis metabolites for shorter periods, while urine and hair samples can reveal use for weeks or even months. In some cases, hair tests have detected cannabis use over 90 days after consumption.
Detection Windows for Various Cannabis Drug Tests
Urine Tests
Among all drug tests, urine testing is the most commonly used method for screening for drug use in an individual.
Detection times vary, but a 2017 review suggests the following windows for cannabis in urine after last use:
– Single-use (e.g., one joint): up to 3 days
– Moderate use (around 4 times a week): 5–7 days
– Chronic use (daily): 10–15 days
– Chronic heavy use (multiple times daily): over 30 days
Blood Tests
Blood tests generally detect recent cannabis use, typically within 2–12 hours after consumption. However, in cases of heavy use, cannabis has been detected up to 30 days later. Chronic heavy use can extend the detection period in the bloodstream.
Saliva Tests
THC can enter saliva through secondhand cannabis smoke, but THC metabolites are only present if you’ve personally smoked or ingested cannabis.
Saliva testing has a short detection window and can sometimes identify cannabis use on the same day. A 2020 review found that THC was detectable in the saliva of frequent users for up to 72 hours after use, and it may remain in saliva longer than in blood following recent use.
In areas where cannabis is illegal, saliva testing is often used for roadside screenings.
Hair Tests
Hair follicle tests can detect cannabis use for up to 90 days. After use, cannabinoids reach the hair follicles through small blood vessels and from sebum and sweat surrounding the hair.
Hair grows at approximately 0.5 inches per month, so a 1.5-inch segment of hair close to the scalp can reveal cannabis use over the past three months.
Factors Affecting THC and Metabolite Retention
The length of time THC and its metabolites stay in your system depends on various factors. Some, like body mass index (BMI) and metabolic rate, relate to individual body processing, not the drug itself.
Other factors are specific to cannabis use, including:
– Dosage: How much you consume
– Frequency: How often you use cannabis
– Method of consumption: Smoking, dabbing, edibles, or sublingual
– THC potency: Higher potency can extend detection time
Higher doses and more frequent use generally extend THC retention. Cannabis consumed orally may remain in the system slightly longer than smoked cannabis, and stronger cannabis strains, higher in THC, may also stay detectable for a longer period.
How Quickly Do the Effects of Cannabis Set In?
When smoking cannabis, effects appear almost immediately, while ingested cannabis may take 1–3 hours to peak.
The psychoactive component THC produces a “high” with common effects such as:
– Altered senses, including perception of time
– Mood changes
– Difficulty with thinking and problem-solving
– Impaired memory
Other short-term effects can include:
– Anxiety and confusion
– Decreased coordination
– Dry mouth and eyes
– Nausea or lightheadedness
– Trouble focusing
– Increased appetite
– Rapid heart rate
– Restlessness and sleepiness
In rare cases, high doses may lead to hallucinations, delusions, or acute psychosis.
Regular cannabis use may have additional mental and physical effects. While research is ongoing, cannabis use may increase the risk of:
– Cognitive issues like memory loss
– Cardiovascular problems including heart disease and stroke
– Respiratory illnesses such as bronchitis or lung infections
– Mood disorders like depression and anxiety
Cannabis use during pregnancy can negatively impact fetal growth and development.
Duration of Effects
Short-term effects generally taper off within 1–3 hours, but for chronic users, some long-term effects may last days, weeks, or even months. Certain effects may even be permanent.
Bottom Line
The amount of time that cannabis remains in your system following a single use varies greatly depending on individual characteristics such as body fat, metabolism, frequency of use, and mode of intake. Frequent users may maintain traces of THC for weeks, whereas infrequent users may test positive for as little as a few days. Hair tests can disclose usage for up to 90 days, while blood and saliva tests identify more recent use. Urine tests are the most popular and have varying detection durations. The duration that THC and its metabolites are detectable will ultimately depend on a number of factors, including dose, strength, and individual body chemistry.
PEE IN A CUP COMING UP, READ ON..
Is kratom addictive? Discover the potential for dependence on Kratom, the risks involved with its use, and how to approach its consumption responsibly.
From 2011 to 2017, over 1,800 calls to poison centers involved kratom in the U.S. This significant number highlights the concern regarding kratom addiction.
However, without Food and Drug Administration (FDA) oversight, and due to various consumption methods like teas and capsules, there are significant health risks. Safe use of kratom is now in question due to these issues.
Research debates how dependence develops, outlining signs like loss of control and withdrawal symptoms. These signs are seen in regular kratom users. Ironically, some people switch from drugs like heroin to kratom, looking for a legal alternative.
Understanding Kratom: Origins and Prevalence
Kratom comes from the Mitragyna speciosa tree in Southeast Asia. It can act like a stimulant or like opioids, based on how much you take. People use it in different ways, for a small energy boost or stronger effects at higher doses.
The legal status of kratom in the U.S. is complicated and changing. It’s a hot topic because some worry about its misuse. It’s still legal in several states. This shows how different places handle drug rules. The National Institute on Drug Abuse is looking into its medical benefits. But, the FDA hasn’t approved it for medical use yet. The DEA calls it a “drug of concern,” which means policies might change.
-
From 2011 to 2017, poison control centers in the U.S. got over 1,800 reports about kratom. This shows it’s widely used and might pose health risks.
-
Kratom’s main ingredients bind to opioid receptors very strongly, stronger than morphine even. This fact is key to understanding its effects.
-
As more people use kratom, more are reporting serious health problems. These include liver and heart issues, and tough withdrawal symptoms, particularly in those already sick.
The statistics show mounting worries about kratom in the U.S. As its use grows, it’s becoming more important to health policies and laws. What happens next will depend on further research and legal decisions.
Is Kratom Addictive: Investigating the Substance’s Nature
The question of kratom’s addictiveness focuses on how it affects brain receptors and its long-term health implications. The ongoing debate highlights concerns about dependence and the risk of addiction. Scientists are closely looking at these issues.
How Kratom Works in the Brain
Kratom’s main alkaloids, mitragynine and 7-hydroxymitragynine, bind to the brain’s opioid receptors, similar to painkillers and narcotics. This connection suggests a potential risk of dependence. These alkaloids are key to kratom’s pain relief but also point to possible addiction concerns, especially with frequent, high-dose usage.
Patterns and Consequences of Long-term Use
-
Using kratom often, especially in large doses, can increase the risk of dependence and intense withdrawal symptoms, similar to opioid withdrawal.
-
Although some use it for pain or to improve mood, long-term kratom users might see serious health problems, like liver damage and mental health issues.
-
Withdrawal symptoms, including irritability, nausea, and sleep problems, show kratom’s impact on one’s physical and mental health.
Assessment of Addiction Risks
Studies indicate a significant risk of addiction to kratom, especially with high doses or frequent use. Dependence develops as the body gets used to kratom, leading to tolerance and a need for more to feel its effects. Withdrawal symptoms emphasize this risk, as highlighted by health experts.
Physiological Effects: Kratom’s Impact on the Body
There is a lot of debate about the safety and use of kratom. This herbal extract comes from the Mitragyna speciosa plant. It has drawn attention for its possible harmful effects on the body. The FDA has issued many warnings about kratom, raising safety concerns.
-
Kratom Adverse Effects: Kratom users have reported side effects like nausea, vomiting, and confusion. More serious issues include high blood pressure and liver damage. These problems highlight the risks of using kratom.
-
Herbal Extract Safety: Some kratom products contain heavy metals and pathogens. These can cause severe health issues, including death. This shows the importance of safety in herbal products.
-
FDA Warnings and Regulations: The FDA has linked kratom to over 35 deaths and warns against using it. They point out the lack of medical uses and the risk of addiction.
-
Physiological Impact: Kratom’s effects depend on the dose and the user’s body. Yet, it can lead to dangerous outcomes like liver damage and seizures.
-
Safety Concerns from Authorities: Federal agencies like the DEA are worried about kratom’s safety. Although not a controlled substance, monitoring suggests users should be careful.
Kratom might offer temporary relief for some ailments, but it comes with significant risks. The FDA’s warnings should make people think twice. If considering kratom, it’s crucial to talk to a doctor first. Experts stress the need for safety and caution with herbal extracts.
Conclusion
Kratom’s role in health and regulation is complex, with views and research findings widely varied. Some people use kratom for its claimed health benefits, but it’s a hot topic. Experts advise caution and suggest consulting a doctor before using kratom due to the unclear effects.
Clinical studies using scores like SOWS and COWS haven’t confirmed withdrawal symptoms from kratom. This adds to the debate, especially when some users report withdrawal. This makes kratom a controversial subject among different findings and user experiences.
When it comes to treating opioid addiction, kratom can be both helpful and harmful. Some have used it successfully to fight addiction. Yet, some states have banned it. This highlights the need for regulations and consistent product quality. It also raises questions about kratom’s legal status due to mixed actions by authorities.
The situation shows how complex kratom is in the realm of substance use and law. Without clear evidence supporting either its benefits or risks, it poses a challenge. More research is needed to guide regulations and health advice. For now, anyone thinking of using kratom should be careful, seek medical advice, and keep up with laws and health guidelines.
WHAT IS KRATOM ANYWAY? READ ON…
Webinar Replay: Post-Election Cannabis Wrap – Smoke ’em if You’ve Got ’em
I Had Just One Puff
Marijuana firms Eaze, Green Dragon find new life after $10 million capital infusion
Get some rest on Modified Grapes—November’s Leafly HighLight
Is Kratom Addictive? Understanding Dependence, Risks, and Safe Usage
New Rule, December 5: Oregon Cannabis Retailers, Processors and Labor Peace Agreements
The CBD Dog Treat Guide
Trippin’ Golf Balls – Can Magic Mushrooms Help Your Golf Game?
Australian Broadcasting Corp Alleges Military Veterans Have Been Targeted By Medicinal Cannabis Companies Via Social Media & Offered Free “Product”
Medical Marijuana Passed in 106 out of 106 Counties and Cities in What State? A. Florida B. Kentucky C. Ohio D. North Dakota
Distressed Cannabis Business Takeaways – Canna Law Blog™
United States: Alex Malyshev And Melinda Fellner Discuss The Intersection Of Tax And Cannabis In New Video Series – Part VI: Licensing (Video)
What you Need to Know
Drug Testing for Marijuana – The Joint Blog
NCIA Write About Their Equity Scholarship Program
It has been a wild news week – here’s how CBD and weed can help you relax
Cannabis, alcohol firm SNDL loses CA$372.4 million in 2022
A new April 20 cannabis contest includes a $40,000 purse
Your Go-To Source for Cannabis Logos and Designs
City Of Oakland Issues RFP For Employee Training Programs
-
Cannabis News2 years agoDistressed Cannabis Business Takeaways – Canna Law Blog™
-
One-Hit Wonders2 years agoUnited States: Alex Malyshev And Melinda Fellner Discuss The Intersection Of Tax And Cannabis In New Video Series – Part VI: Licensing (Video)
-
Cannabis 1012 years agoWhat you Need to Know
-
drug testing11 months agoDrug Testing for Marijuana – The Joint Blog
-
Education2 years agoNCIA Write About Their Equity Scholarship Program
-
Cannabis2 years agoIt has been a wild news week – here’s how CBD and weed can help you relax
-
Marijuana Business Daily2 years agoCannabis, alcohol firm SNDL loses CA$372.4 million in 2022
-
California2 years agoA new April 20 cannabis contest includes a $40,000 purse