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Ocular Effects of Substance Use – How and Why Drugs Change Your Eyes

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Eyes are the windows to the soul. You can tell a lot about a person by looking into their eyes, like how they’re feeling, if they’re lying about something, and often times, if they’re high on drugs. While not all substances affect our eyes the same way, most of them do impact our peepers in some way. From pupil dilation and constriction to bloodshot, watery eyes, it’s a very common and simple way to determine if a person may be on drugs, and which ones.  

Ocular manifestations of drug use 

One of the significant side effects from drugs is changes in the appearance of the eyes, including the pupil’s motion and size and the color of the whites. Many drugs from illicit ones to legal substances to prescription drugs, in all different classes from cannabis to opiates to amphetamines, all of them have effects on the eyes.  

Some of these effects are short term, like the ones mentioned above, while some are more severe and can lead to lasting changes in vision. For now, we’ll focus on the former, immediate effects that indicate current intoxication. These include bloodshot and/or watery eyes, dilated pupils, and pinpoint pupils.  

Bloodshot eyes 

Many irritants like make-up and various chemicals, medical conditions such as allergies, and several different substances can cause red, bloodshot, eyes – which is a result of expanding blood vessels in the sclera. Chronic dry eye can also cause redness in the eyes, as your body is not producing enough tears to keep them properly lubricated.  

Again, there are many different drugs that can make your eyes red but most commonly, you see it when people drink too much alcohol, smoke weed, or use cocaine. As a regular pot smoker that also suffers from chronic dry eye, I use eyedrops pretty much anytime I leave the house, just to not look like I’m baked out of my mind while out in public.  

Dilated pupils  

Some substances trigger the body’s fight or flight adrenaline response by interacting with serotonin and adrenergic receptors in our sympathetic nervous system. This chemical reaction leads to mydriasis, the muscle relaxation that allows the eye’s pupil to expand and let in more light. Pupils also dilate naturally due to changes in light and emotional events, for example, pupils can dilate when a person is scared, stressed, or sexually aroused.  

Close up of a very dilated pupil

Stimulants are most commonly cause pupil dilation. However, this symptom can result from ingesting alcohol, cocaine, cannabis in rare cases, and it’s pretty common with most hallucinogens as well such as MDMA, psilocybin, LSD, and ketamine. SSRI antidepressants are also known to cause pupil dilation. What’s also interesting is that opiates cause the opposite effect, constriction of the pupils, but opioid withdrawal can cause the pupils to dilate. 

I’ve experienced pupil dilation when using MDMA and psilocybin, but since I typically use those types of drugs at night, I didn’t really notice any changes to my vision. In my younger years, I sometimes used ecstasy during the day, and I do remember feeling like my eyes were more sensitive to sunlight – sunglasses were my best friend. As a matter of fact, I’ve met people who were rolling and wore their sunglasses at night too, so I guess the struggle is real for some.   

Pinpoint pupils  

Whereas dilation due to activation of the sympathetic nervous system, it’s stimulation of the parasympathetic system, known for “rest and digest” functions, that causes constriction, or pinpoint pupils. Pinpoint pupils appear and remain very small even in darkness. 

Pupil constriction can have natural causes, like exposure to bright lights and aging. It’s also a side effect of certain medications, or could be caused by hemorrhaging or poisoning. It can also indicate opiate use, but unlike dilated pupils, pinpoint pupils are often a sign of a possible overdose. If your friend or family member displays this symptom and their eyes are not responding to light, call 911 immediately.  

Other central nervous system depressants like benzodiazepines (e.g., Xanax, Valium) and barbiturates (e.g. phenobarbital) can cause pinpoint pupils. These drugs act on the brain’s GABA receptors, which play a role in pupil size regulation. 

Other effects

In addition to the above-listed side effects, which are the most frequently discussed, there are quite a few other eye-related tells that point to intoxication. For example, when people use alcohol, opiates, and other downers, it’s common to experience heavy, droopy eyelids. From an outsider’s perspective, it almost looks like the person is starting to fall asleep because their eyes will barely stay open.  

Heavy eyelids that make a person look like they’re nodding off are common

With amphetamines, twitching can happen pretty often. This can be in various parts of the body, but it does often occur in the eyelids. It can be subtle, but sometimes it’s extremely noticeable. Other ocular symptoms can include blurred vision (common when people drink too much, but other substances can cause this too), slowed reaction time or jerky eye movements (which is why police ask suspects to follow their fingers when testing for sobriety), and glazed over eyes (stoned eyes).   

Final Thoughts

Listen to the eyes, they have much to say; especially when it comes to a person’s current state of mind. Again, it doesn’t really matter what class of drugs you’re talking about, most of them have some type of effects on the eyes. Some are very obvious, like extremely dilate pupils or severe twitching, but some can be more subtle, or can be attributed to many other causes, like redness. So whether you’re checking for drug use in someone else, or trying to hide your own drug use, remember to always take a quick glance at your eyes before doing something important.

Hello readers. We’re happy to have you with us at Cannadelics.com; a news source here to bring you the best in independent reporting for the growing cannabis and hallucinogen fields. Join us frequently to stay on top of everything, and subscribe to our Cannadelics Weekly Newsletter, for updates straight to your email. Check out some awesome promos for cannabis buds, smoking devices and equipment like vapes, edibles, cannabinoid compounds, magic mushroom products, and a whole bunch more. Let’s all get high together!



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Cannabis Consumers Are Being Hit By The Tariffs

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Tariffs are the word of the day – but marijuana consumers need to be ready to see a change also.

From apples to automobiles, hundreds of industries are trying to figure out the new tariffs.  What is clear is prices are going up on a random amount of things.  But, why is a surprise, is cannabis consumers are being hit by the tariffs also. Although cannabis itself cannot be imported or exported due to federal restrictions, the industry heavily relies on international suppliers for key components like vaporizer hardware, packaging, and cultivation equipment.

RELATED: Mixed Messages From The Feds About Cannabis

For instance, products sourced from China now face cumulative tariffs as high as 45%, including a 10% increase imposed in February 2025. Similarly, imports from Canada and Mexico face 25% tariffs. These measures have particularly affected items like vape cartridges, batteries, and specialized packaging materials, which are difficult to source domestically at competitive prices. As a result, many cannabis companies are passing these increased costs down the supply chain to consumer

The financial burden of these tariffs is substantial. Analysts estimate that most cannabis businesses lack the margin flexibility to absorb a 10%-15% cost increase. This has led to higher retail prices for products like pre-rolls and vaporizers, potentially pushing consumers toward cheaper, unregulated black-market alternatives. Such a shift raises concerns about product safety and could undermine the legal market’s growth.

Additionally, the tariffs have caused stock prices of major cannabis companies like Tilray Brands and Canopy Growth to decline by 5%-10%, reflecting investor concerns over profitability.Smaller businesses, already constrained by high taxes and limited banking access, are particularly vulnerable to these economic pressures.

Efforts to mitigate tariff-related expenses include exploring alternative manufacturing locations in countries like Malaysia or India. However, transitioning production is complex and time-consuming due to logistical hurdles and regulatory compliance requirements. Domestic production is another option but often comes with higher costs and limited capacity.

RELATED: How To Be Discreet When Using Weed

Packaging regulations in many states exacerbate the situation by requiring child-resistant designs, further limiting affordable domestic alternatives. Some companies are exploring sustainable packaging solutions as a long-term strategy to reduce dependence on volatile international markets.

The ongoing trade tensions show no signs of easing under Trump’s administration, leaving cannabis businesses with little choice but to adapt quickly. Strategies such as diversifying suppliers, investing in automation, and innovating with local materials may help companies weather the storm. However, without significant policy shifts or financial support mechanisms, the industry faces a challenging road ahead.



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Cannabis Can Help A Sore Throat

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There is a buzz about sore throats today. While they are most common in colder months, spring allergies bring the pain also. This is often due to postnasal drip, which is when mucus from the nose and sinuses drains down the back of the throat, causing irritation and a scratchy feeling. Overuse of the voice, like talking loudly or singing for long periods, can tire out and strain the muscles in your throat, causing them to feel sore. The good news is cannabis can help a sore throat.

RELATED: How Hemp Helps You Sleep

For those seeking natural alternatives to manage cold symptoms, cannabis is emerging as a promising option for throat irritation. Increasing research at medical center specifically targeting sore throats shows early insights. The data suggests cannabinoids and terpenes could offer symptom relief through their unique properties.

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Photo by Esther Kelleter / EyeEm/Getty Images

Cannabis contains compounds like THC and CBD, which studies indicate possess anti-inflammatory properties that may reduce throat swelling and irritation. Terpenes such as eucalyptol—found in some strains—are traditionally associated with decongestant effects, potentially easing respiratory discomfort. These components work synergistically to calm inflamed tissues, though their direct impact on sore throats requires further clinical validation.

Smoking cannabis while ill remains controversial due to potential throat irritation from heat and smoke. Instead, experts recommend gentler options:

  • Edibles/lozenges: THC or CBD-infused products bypass inhalation, delivering localized relief without aggravating the throat.

  • Cannabis tea: Warm beverages with cannabis extracts may soothe scratchy throats while providing hydration.

  • Tinctures: Sublingual CBD oils allow precise dosing and avoid respiratory irritation.

Beyond direct throat relief, cannabis may improve overall wellness during illness. THC’s appetite-stimulating properties can combat reduced hunger, while its relaxing effects might promote restorative sleep. CBD’s muscle-relaxing qualities could help alleviate the body aches often accompanying colds.

RELATED: How To Stop Coughing So Hard From Marijuana Smoke

While preliminary findings are encouraging, users should consult healthcare providers before combining cannabis with conventional cold medications due to potential interactions. Starting with low-dose CBD products may offer benefits without psychoactive effects. As legalization expands, more targeted research is expected to clarify cannabis’s role in respiratory health.

Innovative cannabis formulations—from throat-calming lozenges to anti-inflammatory teas—are redefining how we approach minor ailments. For those navigating cold season, these plant-based solutions present a compelling fusion of traditional herbal wisdom and modern cannabinoid science

 



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White House Finally Comments On Marijuana Industry

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Part of the cannabis industry supported the new president, betting he was going to move and move quickly on cannabis – the White House finally commented.

The cannabis industry has been a boon for consumers, medical patients, veterans and legal states, but for the thousands of mom and pop businesses is has been a roller coaster.  With a huge demand, it would seem to be easy money, but the federal, tax, and banking restrictions have made it difficult to grow and expand. Part of the industry were all for the new administration assuming they would support positive change, but many in the new cabinet and the House Speaker Mike Johnson are foes.  Now the White House finally comments on marijuana industry…and it doesn’t show a clear path.

RELATED: Music Is A Turn On Like Sex And Marijuana

The administration’s current stance on marijuana reform is marked by inaction, despite campaign promises and earlier signals of support for cannabis-related reforms. A White House official recently confirmed that “no action is being considered at this time” regarding marijuana policy, leaving advocates and industry stakeholders uncertain about the administration’s priorities.

During his campaign, the resident expressed support for rescheduling marijuana under the Controlled Substances Act (CSA), which would move it from Schedule I to Schedule III, easing restrictions on medical use and enabling cannabis businesses to access banking and tax benefits. However, since taking office, no concrete steps have been taken to advance this initiative. A DEA hearing on rescheduling, initially planned for January 2025, was postponed due to procedural appeals and remains unscheduled.

The president has also voiced support for state autonomy in cannabis policy and endorsed state-level legalization initiatives, such as Florida’s failed 2024 ballot measure for recreational marijuana. While this reflects a more favorable stance compared to his first term, his administration has yet to prioritize federal reforms like the SAFE Banking Act, which would facilitate banking services for cannabis businesses. Efforts to include such measures in a government funding bill late last year were unsuccessful.

The delay in federal action has significant implications for the cannabis industry. Rescheduling marijuana could alleviate financial burdens by eliminating restrictions under IRS Code Section 280E and promoting medical research. However, the stalled process leaves businesses navigating regulatory uncertainties and limited financial access.

RELATED: The Science Behind Why Music Sounds So Much Better When You’re High

While stakeholders continue lobbying for reform, the administration appears focused on other priorities such as immigration and foreign policy. Advocates hope the President will leverage his influence to advance cannabis reform, but for now, the issue remains sidelined. Until then the industry struggles and waits.



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