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Pancreatic Cancer And Chemo And CBD

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Out of all types of cancers that exist, which type do you think is one of the hardest to beat? On a worldwide scale, pancreatic cancer is one of the deadliest forms of cancer in regards to overall survival rates.  Now research has given a small ray of hope for pancreatic cancer and chemo and CBD.

According to the American Cancer Society, amongst the combination of all stages of pancreatic cancer, the survival rate for one-year is 20%, and the survival rate for five years is under seven percent. Although certain cancer treatments are commonly used such as chemotherapy and radiation, in a recent study, it has been found that the combination of chemotherapy and cannabidiol (CBD) treatments have led to significant pancreatic cancer survival rates.

Research Findings on Cannabidiol (CBD) and Chemotherapy Cancer Treatments

In the recent study mentioned above, mice that were diagnosed with pancreatic cancer received CBD administration alongside chemotherapy treatments. As a result of this combination, it was discovered that the mice with CBD and chemotherapy treatments survived close to three times longer than the mice that were only treated with chemotherapy.

RELATED: Marijuana As Treatment For Prostate Cancer: Here’s What Doctors Know

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In general, this study’s findings provide more valid reasoning for human testing. Although this study hasn’t been conducted on humans yet, the released results demonstrate the need to further investigate and study cannabis compounds, especially CBD.

Grim Pancreatic Cancer Survival Rates

Overall, pancreatic cancer is the twelfth most common cancer on a worldwide scale. Also, the highest occurrence of this type of cancer is in developed countries. Unfortunately, the overall survival rate for pancreatic cancer is quite grim. In particular, Marco Falasca, a lead researcher at Queen Mary University of London stated the following about the life expectancy of pancreatic cancer:

“The life expectancy for pancreatic cancer patients has barely changed in the last 40 years because there are very few, and mostly only palliative care treatments available. Given the five-year survival rate for people with pancreatic cancer is less than seven percent, the discovery of new treatments and therapeutic strategies is urgently needed.”

With this being said, due to the recent results derived from the mice study, there’s a strong need to further examine CBD and its potential in treating different types of cancer, especially pancreatic.

Cannabidiol’s Medicinal and Anti-cancer Properties

When it comes to CBD, thus far, it has been found that it’s an extremely medically beneficial cannabinoid, and it contains both anti-tumoral and neuroprotective properties, which can help those who have been diagnosed with cancer. However, CBD has also demonstrated its anti-nausea and antiemetic (anti-vomiting) properties. These properties have proven to be very effective for those undergoing chemotherapy and other cancer-related therapies. Additionally, Cannabidiol has been found to improve the side effects caused by chemotherapy, especially vomiting, nausea, and pain.

If human testing is conducted on the combined topic of pancreatic cancer, CBD, and chemotherapy treatments, this would build upon past animal research findings. Specifically, one study discovered CBD’s possible anti-cancer properties, and another study found CBD to be a potential anti-cancer drug.

Ask Dr. Green: How Can I Use Marijuana To Deal With Chemotherapy?
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Legality of CBD in the United States and the United Kingdom

Moreover, due to the cannabis legality differences between America and the United Kingdom, it’s likely that the conduction of human trials with a focus on CBD would progress faster in the UK than in the U.S. The reason for this is because currently, the cannabis plant remains a Schedule I illegal substance in the U.S., and CBD is a cannabinoid found in the cannabis plant. Whereas, in the UK, CBD has been approved for usage and research purposes.

RELATED: Cannabis Flavonoid Could Provide Breakthrough Treatment Against Pancreatic Cancer

Therefore, researchers and scientists based in England can legally test this cannabinoid in human clinical trials, according to Dr. Falasca. Nonetheless, the U.S. is progressing slowly but surely, especially because the U.S. FDA recently approved of a CBD-based drug called Epidiolex for the treatment of epilepsy. This specific drug approval was a significant move since it’s the first U.S. FDA-approved drug that contains a cannabinoid derived from cannabis.

Overall, since pancreatic cancer is one of the deadliest forms of cancer, it would be in the general public’s best interest to have access to a natural form of medicine for cancer treatments such as CBD rather than just chemotherapy and radiation. Due to the noteworthy results that were released from the mice study discussed above, it’s likely that Cannabidiol will be further studied and investigated moving forward, especially for cancer treatment purposes.



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What To Know About Chemotherapy And Cannabis

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Even the hesitant becomes curious about medical marijuana when dealing with chemotherapy.  Studies have shown medical marijuana in the right dose can help relieve some of the side effects of chemotherapy. Nearly 25% of cancer patients receive chemotherapy during a given year.   And the exhaustion is real and could last months even when the treatments are over.

Data demonstrates you can take cannabis with chemo and radiation, but it is wise to have a conversation with your oncologists as you consider blending it in to your regimen. Cancer is a life-threatening illness which knows no boundaries.  The medical community is now open and researching on how to use the benefits of medical marijuana for healing parts of cancer.  Here is what to know about chemotherapy and cannabis.

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During chemotherapy, cancer patients experience a range of side effects. If you’re on a strong chemo regimen, usually the day after is when you’ll experience the worst symptoms and symptoms range from dizziness to nausea and vomiting. Patients need chemotherapy because it is a powerful treatment that kills the body’s growing cancerous cells, however, these side effects often make it a gruesome experience.

Aside from the fact that cannabis helps to mitigate some of the symptoms associated with chemotherapy, it also plays a supportive role in helping the body fight back cancerous cell growth when they get into chemotherapy and radiation.

One of the earliest side effects of chemotherapy is feeling nauseous, which is a disrupting factor for cancer patients. Many patients undergoing chemo complain of feeling excessively tired, headaches, high body temperatures and so on. By incorporating cannabis with chemotherapy you can significantly reduce the bulk of these side effects.

Like most medications, medical marijuana works over a period of tine with the right dosage. Taking it once doesn’t always provide the greatest benefits immediately.

A key benefit is it helps with a patients appetite, which is important for body maintenance. Patients complain after chemo they couldn’t eat or feel hungry.  With cannabis, often the appetite returns with an increased craving for food and an urge to snack more.

Another side effect of chemotherapy is exhaustion. Coupled with feeling overwhelmed by the process they end up mental and physical challenged to move forward.  A sativa “wakes” the body up and helps through the difficult times. CBD and THC posess properties that can keep patients alert and active throughout the chemo treatment process.

RELATED: CBD And Chemo Combo Increases Cancer Survival Rates

Another side effect can be insomnia, despite the exhaustion, they struggle to have a decent sleep. Since chemo patients are given steroids beforehand to help with the side effects, the majority also experience insomnia. Combining cannabis can help patients feel well-rested throughout the day, thus making it easier to sleep.

RELATED: Here’s How Marijuana Can Kick Chemotherapy-Induced Nausea To The Curb

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You may feel exhausted when combining cannabis or any other medication with chemotherapy. It can be an overwhelming experience if it isn’t done right. Here are some pointers to help you derive the best from using cannabis:

  • Always start low and go slow: don’t take so much cannabis at the same time.
  • Always consult your doctor or oncologist if you feel like you need to take more or lessen your dosage
  • Avoid using too many products simultaneously: sometimes, you may not get the best out of cannabis because you are taking too much medicine.
  • Cannabis is very safe when used with a doctor’s guidance.
Ask Dr. Green: How Can I Use Marijuana To Deal With Chemotherapy?
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Patients are often concerned about the “method of application” of cannabis when they are in chemo: they wonder if they should smoke it, chew it or consume it via other means.  The easiest is through a tincture or oil. Under the tongue and it acts quickly without having to put stress or the lungs and it doesn’t have to be swallowed if there is nausea.  If there is no nausea a gummy or maybe a cannabis beverage can be absorbed, but it may take time.  The last way to consume is either through a vape or smoking.  It is important to discuss this method with your health professional to avoid aggravation of the respiratory system.



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More Marijuana Rescheduling Hints

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Brain cancer has been in the news – it is a devastating diagnosis, but there is hope cannabis could help.

Michael Strahan has gone public with one of his daughters has brain cancer. Since then, she is having a slow recovery she is sharing to bring awareness brain cancer is an all age disease. Over 100,000 people are diagnosed with a primary brain tumor annually. Brain and other CNS tumors are the fifth most common cancer. Over 30,000 children are currently diagnosed with a brain tumor. Over 1 million people are living with a diagnosis of a primary brain tumor and it can be a rough road. Early research suggest medical marijuana may help with brain cancer.

RELATED: Science Says Medical Marijuana Improves Quality Of Life

It is proven cannabis has medical benefits, but more research needs to be done to better define how it can have an impact and help patients. Currently, the evidence that cannabis-based products can treat brain tumours or brain cancer is limited. Preliminary studies from the lab suggest that cannabinoid chemicals THC and CBD can stop glioblastoma (GBM) cells from growing, causing them to die and disrupting the blood supply to the tumour cells.

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There has been some data and research around glioma which looks promising. Glioma is a growth of cells that starts in the brain or spinal cord. The cells in a glioma look similar to healthy brain cells called glial cells. Glial cells surround nerve cells and help them function. As a glioma grows it forms a tumor.

Preliminary studies from the lab suggest that cannabinoid chemicals THC and CBD can stop glioblastoma (GBM) cells from growing, causing them to die and disrupting the blood supply to the tumour cells.

In 2021, an early-stage trial led by Professor Susan Short suggested that adding a specific blend of these chemicals – in the form of a drug called Sativex – to chemotherapy could potentially help treat recurrent GBMs more effectively.

RELATED: The Most Popular Marijuana Flavors

CXannabis-based drug Sativex approved as a prescription medicine. The drug, used in treating multiple sclerosis, was also found to be tolerable in combination with chemotherapy, with the potential to extend survival, in a phase I trial in glioblastomas.

A phase II trial, led by the University of Leeds, is assessing whether adding Sativex – an oral spray containing cannabinoids THC and CBD – to chemotherapy, could extend life for thousands diagnosed with a recurrent glioblastoma. Currently, it has an average survival of less than 10 months.

Scientific research indicates medical cannabis and cannabinoids could become key therapy in modern neuro-oncology; however, further studies are needed to establish outcomes and  dosage.



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Medical Marijuana Reduces Opioid Use

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Opioids and fentanyl driving a crisis in recent years, with the COVID-19 pandemic exacerbating the public’s abuse of the drug. The crisis has also become a major U.S. foreign policy issue.  Massive lawsuits have been filling the courts due to the addictive and damaging nature of some opioids and patients have been left in shambles.  Now, data shows medical marijuana reduces opioid use.

RELATED: 8 Ways to Enjoy Marijuana Without Smoking It

A new study from New York State and CUNY researchers suggests receiving medical cannabis for thirty days or more may help patients on long-term opioid treatment to lower their dose over time.

Medical Marijuana Applications Soaring Under Coronavirus Pandemic
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Another study conducted by the American Medical Association showed positive data.  The study, published in JAMA Oncology, analyzed the results of thousands of patients with different types of cancer. ound an association between receiving medical cannabis for chronic pain for a longer duration and a reduction in prescription opioid dosages among patients on long-term opioid therapy. Patients who were on higher baseline dosages of prescription opioids when they started receiving medical cannabis experienced larger reductions in opioid dosages.

Researchers explained that the study was conducted in order to explore the links that exist between marijuana legalization and opioid use. They concluded that medical marijuana curbed opioid use and provided an alternate route for treatment.

RELATED: Marijuana And Prostate Cancer

“Findings of this cross-sectional study suggest that medical marijuana legalization implemented from 2012 to 2017 was associated with a lower rate of opioid dispensing and pain-related hospital events among some adults receiving treatment for newly diagnosed cancer,” they wrote.

“The nature of these associations and their implications for patient safety and quality of life need to be further investigated,” researchers added.

Medical marijuana has less of an impact on the body and mind. Cannabis can be an effective treatment for pain, greatly reduces the chance of dependence, and eliminates the risk of fatal overdose compared to opioid-based medications. Medical cannabis patients report that cannabis is just as effective, if not more, than opioid-based medications for pain.

With medical marijuana available in 40 states, this is indeed good news for most patients.



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