Cannabis News
Study Says Medical Cannabis Does Not Impair Mental Cognition, But Let Me Tell You About Some of the Other Drugs Mentioned…
Published
11 months agoon
By
admin
As a seasoned psychonautical explorer sampling earth’s cornucopia of altered states, I can assure concerned minds that cannabis ranks among the mildest mood modifiers found growing freely. While offering unique dimensions of consciousness absolutely meriting respect, its cognitive influence barely ripples the pond compared to other avenues.
Sure, a large oral dose of the top-shelf may remove one temporarily from linear processing into swirling impressionistic headspaces. But such psychic swimming remains shallow splashing next to the alien oceanic depths and rocketing velocities possible with other herbs and chemicals.
A two-hit Hoffman bicycle ride or DMT depersonalization contain scarcely comparable psychenautic gravity. Their transcendent peak experiential bandwidths blast through subjective infinity, suspending all constructs of space, time and identity in magmatic hydrogen bliss. Good luck solving math puzzles mid-hyperspace! Or perhaps, you’d experience math in a completely new dimension, unlocking things you’ve never thought of before.
Good ‘ol drug induced neuroplasticity!
Even sniffing mounds of powdered ambition to all-night cocaine ramblings court more serious cerebral dysfunction. Such compulsive dopamine hijacking frequently fuels delusional ideations of grandeur and paranoid psychosis once sleep deprivation kicks in.
Compare these adventures to the friendly confines of some Blue Dream body buzz, tuning sensory acuity towards laughter, dancing and connection. Traversing these playful marijuana meadows around others often heightens communal intuition and camaraderie, not deterioration measuring anywhere near other intoxicant continents.
So while scientific due diligence confirming such relative safety is prudent given reefer madness stigma, let’s retain perspective. Joint-induced “impairment” rates barely a blip for psychonauts measuring cognitive impacts across vaster pharmacopeias. If anything, cannabis comedowns serve as gentler integration terrain after returning from more turbulent travels beyond infinity’s event horizons. The mellow plant provides solid landing gear grounding wanderers back on Earth.
Now that we’ve established some crucial context, let’s explore what researchers discovered examining prescribed cannabis influences on cognition and consciousness more closely…
An Australian study aimed to assess potential cognitive impacts among 40 patients self-administering their prescribed medicinal cannabis products. Researchers monitored effects using both the sophisticated Cambridge Neuropsychological Test Automated Battery (CANTAB) alongside a mobile application called Druid.
I actually interviewed Dr. Thomas Arkell, Druid’s creator, when it launched several years ago. His technology quantifies psychomotor functioning through brief interactive tests on reaction time, balance, divided attention, and inhibition control. This provides an efficient biomarker for subtle neurological impairment from any substance or condition.
Patients in the cannabis study represented demographics commonly prescribed medicinal marijuana – mostly middle aged, many treating chronic pain and sleep disorders. They orally self-dosed oils or inhaled flower per packaged directions then performed multiple CANTAB and Druid cognitive evaluations both before and after consumption.
Intriguingly, rather than decrementing over time as expected, subjects actually improved on certain attention and information processing CANTAB metrics. Their Druid scores exhibited no significant variation either. These counterintuitive findings starkly contradict assumptions that cannabis, even medicinal, impedes cognition.
By contrast, subjects did report feeling progressively more “stoned” and “sedated” on self-assessment scales in the hours after dosing. Those vaping flower containing higher THC described intensified intoxication relative to oil users.
Yet despite acknowledging these subjective drug effects, users demonstrated no corresponding cognitive difficulties – essentially feeling impaired without actual performance relevance.
This substantiates why medicinal cannabis patients describe quality of life improvements and continue accessing marijuana despite claims of risks – it effectively alleviates symptoms without hampering daily mental faculties, especially under doctor supervision optimizing dosage.
The knowledge accords with psychonautic precedents differentiating cannabis from substances like alcohol truly sabotaging cognition temporarily in proportion to intoxication felt. Weed exerts much subtler headspace modulation unlikely disturbing functionality applied judiciously.
But how could detectable psychological influence not seemingly translate into mental performance detriments as commonly assumed? Let’s unravel that fascinating discrepancy next…
A key quandary permeates cannabis cognitive research – those directing studies and policies frequently possess little firsthand psychoactive reference beyond alcohol, the most socially condoned intoxicant. Hence they transfer expectations colored by booze and prohibitionist rhetoric onto analyzing weed. But applying frameworks contrived around vastly dissimilar substances courts confusion.
Because alcohol notoriously ravages critical thinking and control centers at high doses, it makes intuitive sense why lawmakers prohibit operating vehicles or machinery while drunk. Impairment directly and proportionately tracks intoxication felt – the drunker one gets, the more cognition suffers acutely.
So examining cannabis through this lens of familiar behavioral dysfunction, it seems reasonable assuming comparable or even exceeding mental retardation from illicit substances. Especially when long classified as dangerously as heroin simply for psychoactivity.
However, extrapolating thusly overlooks a glaring experiential reality: cannabis influencing cognition bears only crude resemblance to being drunk despite some conceptual overlap. Beyond surface similarities, their neurological mechanisms differ enormously.
Unlike depressants numbing executive function in a dose-dependent manner, cannabis modulates perception more subtly without necessarily compromising reasoning capacity directly.peak psychoactivity still allows clear mental command rather than blackout.
So why the discrepancy from assumptions? Mostly because cannabis intoxication functions unlike alcohol incritical ways – users typically retain lucid memory, comprehension, judgment and behavior control within reasonable levels of use. Only edible overdoses generate comparable dissolution.
This means despite altered headspaces, tasks like driving remain largely executable with modest effort for seasoned consumers. Now novice users or highly potent products do require caution. But blanket equivalence to drunkenness proves unfounded underexamination.
Where alcohol hits login out central circuits in a blunt diffuse manner, cannabis more delicately tweaks consciousness through targeted receptor systems absent shutting higher function down. Drunk causes mechanical failure, stoned taps light switches.
So research crafted by the sober around legal intoxicants frames cannabis effects incorrectly through confirmation bias. Medicine examines molecules, not platitudes. And the molecules reveal a nuanced synchronist herb unlikely cognitively crippling except under special conditions.
If cannabis intoxication only modestly disrupts cognition in recreational contexts, this effect further diminishes in medical settings. This makes sense considering marijuana’s therapeutic attributes arise from dynamic interaction between phytocannabinoids and the human endocannabinoid system.
As receptors modulate platforms balancing vital functions like appetite, pain relief, or sleep cycles, introducing cannabis compounds triggers self-localized activity stabilizing physiological rhythms. It essentially amplifies innate biochemical feedback mechanisms.
So unlike drinking alcohol passively overwhelmed by binding agents blindly depressing central nervous function, medical cannabis activates targeted endogenous infrastructure for tailored symptom management. Rather than numbing organs, it enhances their self-regulatory capacity.
This means patients utilizing cannabis as medicine often feel reduced or nuanced effects relative to recreational counterparts using equal doses without underlying medical necessity. Their bodies immediately redistribute and metabolize compounds directly toward addressing diagnosed deficiencies or inflammation.
While some generalized psychoactivity occurs peripherally, the bulk of cannabis chemistry works immediately alongside internal infrastructure at directed sites instead of indirectly swamping global neurotransmission crudely like booze. Precision balanced synergism transpires rather than blunt toxic overload.
In essence then, an intelligent two-way dialogue manifests between organism and ally herb parsed through critical pathways in real time. This allows self-government and homeostasis to strengthen, not erode underSupported exterior influence.
So unlike drinking’s unilateral domination of faculties through concentration gradients depleting control centers, medical cannabis employs measured bidirectional communication refined over eons of co-evolution. The rapport ripens medicine.
Thus patients note feeling more functional relief and wellbeing with less attention drawn to the plant’s secondary cognitive spice. They often describe a sensation of clouds or cobwebs clearing rather than obscured. Clarity and vitality improves together through mutually understood exchange.
This clinical efficiency and bio-affinity is why cannabis makes potentially ideal, uniquely tuned medicine if applied conscientiously. It interfaces so naturally with our ancient mammalian physiology, echoing delicate biochemical feedback conversations. Harnessing that bond taps profound curative resonance.
No blunt symptomatic substances can compare.
These clinical insights substantiate what underground medicine knew through hard experience and ancient shamanic lineages transmitted regarding cannabis – it is no blunt intoxicant but rather profound ally if respected appropriately.
Beyond superb symptom treatment absent notable cognitive disruption, the plant provides gentle psychoactive initiation opening doors of perception and intuitive states attuning us to deeper aspects of condition rarely addressed in conventional practice.
Where pharmaceuticals excel at brute chemical force intervention aimed narrowly at localized disease and dysfunction, whole plants synergize broadly across dimensions. Their active compounds choreograph multidimensional healing through interdependent workings refined over eons of co-evolution. They encapsulate enduring wisdom.
So cannabis and other organic medicines don’t simply suppress pathology but nurture the organism holistically – elevating moods, tuning energies, aligning psyche and soma into harmonic coherence once more through biochemistries we intuitively comprehend. They activate the healer within through rapport.
This explains the ineffable spirit people describe undergoing transcendent sessions even secularly – sincere experience meeting conscious plant teacher dispensing hard-won lessons through gnosis and empathy. Beyond compound and container dwells personality animating effect. High science has yet to acknowledge this soul.
But beyond mysticism rests potent neuromodulation clinically confirmable if conservatively translated. Because unlike arbitrarily patented pharmaceutical isolates blindly manipulating single targets in biochemical space, cannabis harmonizes myriad metabolic riffs into a symphonic crescendo aligning selfhood. It coaxes wholeness.
If institutional medicine desires understanding this dynamic herb’s exact risk profiles and therapeutic utilities, it must widen narrow chemistry perimeters acknowledging cannabis’ simultaneous material and ineffable natures. Otherwise, half the medicine remains discounted and denied by default.
So can our brightest intellects progress interpreting shamanic truths while gently reintegrating intuitive ways of knowledge into sterile mechanistic frameworks? The gauntlet is thrown as this kind yet formidable plant teacher offers ascension of thought and healing if we cultivate courage facing profound identity beyond atomistic bits.
CANNABIS AND COGNITIVE ABILITY, READ ON…
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Cannabis News
Webinar Replay: Post-Election Cannabis Wrap – Smoke ’em if You’ve Got ’em
Published
19 hours agoon
November 13, 2024By
admin
On Thursday, November 7th, Vince Sliwoski, Aaron Pelley and Fred Rocafort held a post election discussion “Post-Election Cannabis Wrap – Smoke ’em if You’ve Got ’em”. Watch the replay!
Key Takeaways from the “Smoke ’em if You’ve Got ’em – 2024 Post Election Cannabis Wrap” Webinar:
- Panelists:
- Vince Sliwoski: Oregon Business lawyer specializing in cannabis and commercial real estate.
- Aaron Pelley: Experienced in cannabis law since Washington’s legalization in 2012.
- Fred Rocafort: Trademark attorney working closely with the cannabis team.
- Election Results Overview:
- Most 2024 cannabis ballot measures did not pass.
- Florida, South Dakota, and North Dakota saw failures.
- Nebraska became the 39th state to legalize cannabis for medical use when it passed two cannabis initiatives, Initiatives 437 and 438.
- Federal and State-Level Developments:
- Medical use is currently legal in 38 states, and 24 states allow recreational use.
- Republican support for marijuana legalization is growing.
- Federal Policy Implications:
- Schedule III Rescheduling: The process to move cannabis to Schedule III is ongoing, which could significantly impact the industry.
- Importance of Federal Appointments: The future of cannabis policy depends heavily on who is appointed to key positions in the administration.
- International and Domestic Trade:
- Schedule III status could ease import/export restrictions on cannabis.
- Unified control of House, Senate, and presidency might expedite legislative progress.
- Economic and Industry Impact:
- Cannabis stocks experienced volatility post-election, reflecting investor uncertainty.
- Federal legalization and banking reforms are crucial for industry stability and growth.
- Future Outlook:
- The potential for federal rescheduling remains strong, with hearings scheduled for early 2025.
- State-level initiatives and regulatory developments will continue to shape the industry.
“How Long Does One Puff of Weed Stay in Your System?”… This topic can be difficult to answer since it is dependent on elements such as the size of the hit and what constitutes a “one hit.” If you take a large bong pull then cough, it might linger in your system for 5-7 days. A moderate dose from a joint can last 3-5 days, whereas a few hits from a vaporizer may last 1-3 days.
The length of time that marijuana stays in the body varies based on a number of factors, including metabolism, THC levels, frequency of use, and hydration.
Delta-9-tetrahydrocannabinol, or THC, is the primary psychoactive component of cannabis. THC and its metabolites, which remain in your body long after the effects have subsided, are detected by drug tests.
Since these metabolites are fat-soluble, they cling to bodily fat molecules. They could thus take a while to fully pass through your system, particularly if your body fat percentage is higher.
THC is absorbed by tissues and organs (including the brain, heart, and fat) and converted by the liver into chemicals such as 11-hydroxy-THC and carboxy-THC. Cannabis is eliminated in feces at a rate of around 65%, while urine accounts for 20%. The leftover amount might be kept within the body.
THC deposited in bodily tissues ultimately re-enters the circulation and is processed by the liver. For frequent users, THC accumulates in fatty tissues quicker than it can be removed, thus it may be detectable in drug tests for days or weeks following consumption.
The detection time varies according to the amount and frequency of cannabis usage. Higher dosages and regular usage result in longer detection times.
The type of drug test also affects detection windows. Blood and saliva tests typically detect cannabis metabolites for shorter periods, while urine and hair samples can reveal use for weeks or even months. In some cases, hair tests have detected cannabis use over 90 days after consumption.
Detection Windows for Various Cannabis Drug Tests
Urine Tests
Among all drug tests, urine testing is the most commonly used method for screening for drug use in an individual.
Detection times vary, but a 2017 review suggests the following windows for cannabis in urine after last use:
– Single-use (e.g., one joint): up to 3 days
– Moderate use (around 4 times a week): 5–7 days
– Chronic use (daily): 10–15 days
– Chronic heavy use (multiple times daily): over 30 days
Blood Tests
Blood tests generally detect recent cannabis use, typically within 2–12 hours after consumption. However, in cases of heavy use, cannabis has been detected up to 30 days later. Chronic heavy use can extend the detection period in the bloodstream.
Saliva Tests
THC can enter saliva through secondhand cannabis smoke, but THC metabolites are only present if you’ve personally smoked or ingested cannabis.
Saliva testing has a short detection window and can sometimes identify cannabis use on the same day. A 2020 review found that THC was detectable in the saliva of frequent users for up to 72 hours after use, and it may remain in saliva longer than in blood following recent use.
In areas where cannabis is illegal, saliva testing is often used for roadside screenings.
Hair Tests
Hair follicle tests can detect cannabis use for up to 90 days. After use, cannabinoids reach the hair follicles through small blood vessels and from sebum and sweat surrounding the hair.
Hair grows at approximately 0.5 inches per month, so a 1.5-inch segment of hair close to the scalp can reveal cannabis use over the past three months.
Factors Affecting THC and Metabolite Retention
The length of time THC and its metabolites stay in your system depends on various factors. Some, like body mass index (BMI) and metabolic rate, relate to individual body processing, not the drug itself.
Other factors are specific to cannabis use, including:
– Dosage: How much you consume
– Frequency: How often you use cannabis
– Method of consumption: Smoking, dabbing, edibles, or sublingual
– THC potency: Higher potency can extend detection time
Higher doses and more frequent use generally extend THC retention. Cannabis consumed orally may remain in the system slightly longer than smoked cannabis, and stronger cannabis strains, higher in THC, may also stay detectable for a longer period.
How Quickly Do the Effects of Cannabis Set In?
When smoking cannabis, effects appear almost immediately, while ingested cannabis may take 1–3 hours to peak.
The psychoactive component THC produces a “high” with common effects such as:
– Altered senses, including perception of time
– Mood changes
– Difficulty with thinking and problem-solving
– Impaired memory
Other short-term effects can include:
– Anxiety and confusion
– Decreased coordination
– Dry mouth and eyes
– Nausea or lightheadedness
– Trouble focusing
– Increased appetite
– Rapid heart rate
– Restlessness and sleepiness
In rare cases, high doses may lead to hallucinations, delusions, or acute psychosis.
Regular cannabis use may have additional mental and physical effects. While research is ongoing, cannabis use may increase the risk of:
– Cognitive issues like memory loss
– Cardiovascular problems including heart disease and stroke
– Respiratory illnesses such as bronchitis or lung infections
– Mood disorders like depression and anxiety
Cannabis use during pregnancy can negatively impact fetal growth and development.
Duration of Effects
Short-term effects generally taper off within 1–3 hours, but for chronic users, some long-term effects may last days, weeks, or even months. Certain effects may even be permanent.
Bottom Line
The amount of time that cannabis remains in your system following a single use varies greatly depending on individual characteristics such as body fat, metabolism, frequency of use, and mode of intake. Frequent users may maintain traces of THC for weeks, whereas infrequent users may test positive for as little as a few days. Hair tests can disclose usage for up to 90 days, while blood and saliva tests identify more recent use. Urine tests are the most popular and have varying detection durations. The duration that THC and its metabolites are detectable will ultimately depend on a number of factors, including dose, strength, and individual body chemistry.
PEE IN A CUP COMING UP, READ ON..
Cannabis News
Is Kratom Addictive? Understanding Dependence, Risks, and Safe Usage
Published
2 days agoon
November 12, 2024By
admin
Is kratom addictive? Discover the potential for dependence on Kratom, the risks involved with its use, and how to approach its consumption responsibly.
From 2011 to 2017, over 1,800 calls to poison centers involved kratom in the U.S. This significant number highlights the concern regarding kratom addiction.
However, without Food and Drug Administration (FDA) oversight, and due to various consumption methods like teas and capsules, there are significant health risks. Safe use of kratom is now in question due to these issues.
Research debates how dependence develops, outlining signs like loss of control and withdrawal symptoms. These signs are seen in regular kratom users. Ironically, some people switch from drugs like heroin to kratom, looking for a legal alternative.
Understanding Kratom: Origins and Prevalence
Kratom comes from the Mitragyna speciosa tree in Southeast Asia. It can act like a stimulant or like opioids, based on how much you take. People use it in different ways, for a small energy boost or stronger effects at higher doses.
The legal status of kratom in the U.S. is complicated and changing. It’s a hot topic because some worry about its misuse. It’s still legal in several states. This shows how different places handle drug rules. The National Institute on Drug Abuse is looking into its medical benefits. But, the FDA hasn’t approved it for medical use yet. The DEA calls it a “drug of concern,” which means policies might change.
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From 2011 to 2017, poison control centers in the U.S. got over 1,800 reports about kratom. This shows it’s widely used and might pose health risks.
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Kratom’s main ingredients bind to opioid receptors very strongly, stronger than morphine even. This fact is key to understanding its effects.
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As more people use kratom, more are reporting serious health problems. These include liver and heart issues, and tough withdrawal symptoms, particularly in those already sick.
The statistics show mounting worries about kratom in the U.S. As its use grows, it’s becoming more important to health policies and laws. What happens next will depend on further research and legal decisions.
Is Kratom Addictive: Investigating the Substance’s Nature
The question of kratom’s addictiveness focuses on how it affects brain receptors and its long-term health implications. The ongoing debate highlights concerns about dependence and the risk of addiction. Scientists are closely looking at these issues.
How Kratom Works in the Brain
Kratom’s main alkaloids, mitragynine and 7-hydroxymitragynine, bind to the brain’s opioid receptors, similar to painkillers and narcotics. This connection suggests a potential risk of dependence. These alkaloids are key to kratom’s pain relief but also point to possible addiction concerns, especially with frequent, high-dose usage.
Patterns and Consequences of Long-term Use
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Using kratom often, especially in large doses, can increase the risk of dependence and intense withdrawal symptoms, similar to opioid withdrawal.
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Although some use it for pain or to improve mood, long-term kratom users might see serious health problems, like liver damage and mental health issues.
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Withdrawal symptoms, including irritability, nausea, and sleep problems, show kratom’s impact on one’s physical and mental health.
Assessment of Addiction Risks
Studies indicate a significant risk of addiction to kratom, especially with high doses or frequent use. Dependence develops as the body gets used to kratom, leading to tolerance and a need for more to feel its effects. Withdrawal symptoms emphasize this risk, as highlighted by health experts.
Physiological Effects: Kratom’s Impact on the Body
There is a lot of debate about the safety and use of kratom. This herbal extract comes from the Mitragyna speciosa plant. It has drawn attention for its possible harmful effects on the body. The FDA has issued many warnings about kratom, raising safety concerns.
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Kratom Adverse Effects: Kratom users have reported side effects like nausea, vomiting, and confusion. More serious issues include high blood pressure and liver damage. These problems highlight the risks of using kratom.
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Herbal Extract Safety: Some kratom products contain heavy metals and pathogens. These can cause severe health issues, including death. This shows the importance of safety in herbal products.
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FDA Warnings and Regulations: The FDA has linked kratom to over 35 deaths and warns against using it. They point out the lack of medical uses and the risk of addiction.
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Physiological Impact: Kratom’s effects depend on the dose and the user’s body. Yet, it can lead to dangerous outcomes like liver damage and seizures.
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Safety Concerns from Authorities: Federal agencies like the DEA are worried about kratom’s safety. Although not a controlled substance, monitoring suggests users should be careful.
Kratom might offer temporary relief for some ailments, but it comes with significant risks. The FDA’s warnings should make people think twice. If considering kratom, it’s crucial to talk to a doctor first. Experts stress the need for safety and caution with herbal extracts.
Conclusion
Kratom’s role in health and regulation is complex, with views and research findings widely varied. Some people use kratom for its claimed health benefits, but it’s a hot topic. Experts advise caution and suggest consulting a doctor before using kratom due to the unclear effects.
Clinical studies using scores like SOWS and COWS haven’t confirmed withdrawal symptoms from kratom. This adds to the debate, especially when some users report withdrawal. This makes kratom a controversial subject among different findings and user experiences.
When it comes to treating opioid addiction, kratom can be both helpful and harmful. Some have used it successfully to fight addiction. Yet, some states have banned it. This highlights the need for regulations and consistent product quality. It also raises questions about kratom’s legal status due to mixed actions by authorities.
The situation shows how complex kratom is in the realm of substance use and law. Without clear evidence supporting either its benefits or risks, it poses a challenge. More research is needed to guide regulations and health advice. For now, anyone thinking of using kratom should be careful, seek medical advice, and keep up with laws and health guidelines.
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