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Synthetic seeds show a glimpse of the future for cannabis breeding

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3 weeks ago

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When tissue culture laboratories emerged in the 1970s, they quickly became the standard infrastructure for propagating tomatoes, corn, and dozens of other crops. Decades of scientific literature followed, refining formulas and SOPs that made the process reliable at scale. For cannabis, this body of knowledge does not exist, the consequences of the prohibition era. It’s a gap that companies like Microhemp, a tissue culture lab based in Italy, are now working to close. “Tissue culture labs have been around since the 70s,” says Marco Bianco, founder of Microhemp. “But when it comes to cannabis, this is a relatively new space.”

© Microhemp

Set to empty
Scientific failure has made the setup unimaginable. “Tissue culture has been known inside and out since the 70s. Around Cesena, where we are, there are many laboratories, but they work with traditional plants. Italy produces millions of plants in tissue culture every year, but the cloning formula of these plants is very well known to the scientific community. Because of the ban, there is not nearly as much for cannabis.” That’s why Marco says the value of Microhemp lies precisely in discovering the SOPs for tissue culture of cannabis. “We clean and preserve the genetics, and of course we replicate them.”

Before reaching that point, they had to go through the garage phase. That was 2018. “We started the first initial tests in the usual way. However, this could not work, everything became contaminated, which reinforced the belief that we had to create a sterile laboratory.” Thanks to a European grant, the Microhemp laboratory finally became a reality. “We built the lab inside two 12-meter containers. One has a growth chamber, and the other has a lab and a sterile growth chamber.” Notably, Microhemp did not buy off-the-shelf container farms, they acquired empty shipping containers and completely refurbished them to their specifications.

© Microhemp

Micropropagation of cannabis
This hands-on experience became the basis for one of the company’s secondary services: designing tissue culture laboratories and other facilities. But the core business remains micropropagation. “In micropropagation, every month, you triple the material.”

The method seems simple, but it is not. “We start with small plastic pots, with 7 nodes left to grow. We open the pot again, divide the plant into those 7 nodes again and move on to the last 3 pots. If you do this every month, you can produce a huge number of plants, it’s exponential. In a very short time, we build the line, which is millions of the same plants.” Achieving this requires careful planning at every stage. “The plant that I deliver to you today was taken from a sterile environment. To have that plant ready, we started two months before delivery, and before that there is at least two months of planning to reach the final clone. To deliver a plant to the customer, I decided that it would become a real plant four months before delivery. This creates challenges, because we have to be good at managing stocks, but this allows us to make traditional nurseries quite difficult. Our strength is in numbers, what really sets us apart is our cleanliness in GMP work when you do, the most important thing is to start with a plant that you can guarantee is not infected.

Synthetic seeds© Microhemp
Genetic conservation of microhemp can also take the form of synthetic seeds, a striking way of preserving genetics that keeps traits intact for the long term, and has a practical advantage unrelated to biology. “It’s a very convenient option from a purely logistical point of view,” explains Marco. “If a multinational has facilities in several countries and opens a new site in North Macedonia, synthetic seeds are the best way to move a specific genetic. Put the pot in your pocket,” he laughs.

The reality is more nuanced, as Marco is quick to acknowledge. Synthetic seeds cannot yet be germinated in rockwool, a separate laboratory is required on the recipient side. Microhemp has tested a middle solution: a container format that holds the synthetic seed and the grow room in the same container, but mechanically separated. The user drops the seed in the room to initiate the roots. “It wasn’t guaranteed enough. The seed was germinating with reasonable frequency, but not good enough,” says Marco. For now, the project is on hold while the company focuses on scaling up its core micropropagation and lab design services, which, as Marco says, is what a tissue culture lab actually does.

For more information:
Microhemp Srl
Via Giuseppe Verdi 131, 41019 Soliera (MO), Italy
+393351736178
(email protected)
microhemp.it

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State hemp license applications end April 30

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17 hours ago

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April 19, 2026

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Those wishing to grow and process hemp this year must apply for a license from the Minnesota Department of Agriculture (MDA) by April 30. Each license is valid until December 31 of the year it is issued. Graduates must reapply annually to continue in the program. An MDA license is required for individuals and businesses.

So far, about 30 people have applied for the 2026 MDA license, compared to 84 applicants last year.

These licenses are for the cultivation and processing of industrial hemp only. The hemp license application is not for adult use or for growing or selling medical cannabis. The application is also not intended for the sale of hemp-derived cannabinoid products. Information on adult use and medical cannabis is available Office of Cannabis Management (OCM) website.

There are applications of industrial hemp MDA website. Along with the online form, first-time applicants and authorized representatives must submit fingerprints and pass a criminal background check.

There are also several updates for the 2026 season. The extraction of cannabinoids from hemp is now regulated by the OCM, meaning that anyone interested in this type of processing will need a separate licence. The rates have also changed. The base cost of a hemp license is now $400, with an additional $250 per growing or processing location. The previous $250 processor license fee has been removed, but a 5% surcharge now applies to upgrades to MDA’s technology systems.

All authorized representatives listed on an application must pass a background check before being licensed. In addition, each lot of hemp must undergo THC testing before harvest, and each official sample collected by the MDA costs $100.

Source: Minnesota Department of Agriculture










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Colorado Marijuana Officials Announce Crackdown On Sales Of Hemp Products Amid ‘Risks To Public Safety’

Published

18 hours ago

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April 18, 2026

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These issues “pose serious risks to public safety, market integrity, and the tax revenue framework that supports Colorado’s regulated cannabis industry.”

By Christopher Osher, ProPublica and Evan Wyloge, The Denver Gazette

This story was originally published by ProPublica.

Colorado regulators announced Monday that they plan to crack down on companies that sell cheaper, potentially dangerous, illegal hemp products as marijuana.

The state’s Division of Marijuana Enforcement said it had identified “compliance issues” that threaten to dismantle the marijuana industry in the nation’s first legal retail market.

These problems “pose serious risks to public safety, market integrity and the tax revenue framework that supports Colorado’s regulated cannabis industry,” the agency said in an industry newsletter.

An investigation by the Denver Gazette and ProPublica in January reported that despite Colorado being one of the first states to ban the sale of intoxicating hemp products, the legislature and regulators. he failed adopting many of the rules that other states have used to keep hemp products off the medical marijuana shelves.

Creating evaporative and edible liquid distillate from hemp is much cheaper than using marijuana, giving companies a competitive advantage.

But regulators say they are concerned that manufacturers are relying on toxic and dangerous chemicals to convert the non-toxic CBD compound that is predominant in hemp into THC, the psychoactive compound that makes people feel high. Regulators have banned this chemical synthesis, saying they fear chemical residues could remain in the finished product, putting consumers at risk.

Colorado manufacturers have taken advantage of loopholes in the state’s testing and enforcement system to continue using hemp to make products marketed as marijuana, even though doing so is against state law, according to regulatory studies, previous agency bulletins and testimony and lab results contained in several lawsuits.

In 2024, state investigators found that a popular brand of marijuana sold at dispensaries was not only derived from hemp, but also contaminated with methylene chloride, the chemical often used to convert CBD from hemp into THC. Marijuana is banned by Colorado regulators and banned for most uses by the US Environmental Protection Agency because it can cause liver and lung cancer and damage the nervous, immune and reproductive systems.

Ware House, the company that manufactured these vaporizers, relinquished its marijuana license in response to the investigation. Ware Hause’s owner, Thanh Hau, and the company’s lawyer declined to comment.

Congress passed a law last November that bans nearly all hemp products nationwide starting this fall, but it’s unclear how the government will enforce the ban, and hemp growers are reeling.

In December, President Donald Trump issued an executive order telling his aides to work with Congress to develop rules that could allow certain hemp products.

The Colorado Division of Marijuana Enforcement made the announcement Monday newsletter agency officials stated that they “identified and investigated evidence” that marijuana companies are using illegal practices and prohibited methods to manufacture products, instead of relying on marijuana, which is supposed to be monitored for safety.

The Colorado Hemp Association and the Colorado Hemp Education Association did not immediately respond to requests for comment.

Beyond safety concerns, the bulletin also noted that some marijuana manufacturers and growers are avoiding marijuana tax obligations through “a pattern of non-compliance” in sales operations they report to the state’s “seed-to-sale” tracking system, which tracks marijuana from the initial planting to the sale of flower, vapes and other products at dispensaries.

Companies misrepresent marijuana sales at nominal prices, in some cases as low as $1 per pound for unprocessed marijuana material, the newsletter said. Those products typically fetch more than $600 per pound on the market, depending on the category of marijuana, according to industry experts.

That fraudulent reporting has stolen millions of dollars in marijuana taxes from state and local governments, industry experts say, though no official estimate is available.

The agency said it will follow emergency rules to address these issues. The bulletin emphasized that suspicious and abnormal transactions and inventories detected by the state will prompt investigations. Companies caught using hemp or other illegal material passed off as marijuana face “immediate product embargo, license suspension or revocation, significant fines and law enforcement,” regulators warned.

The Denver Gazette and ProPublica have tried to track the anomalous transactions, but the Division of Marijuana Enforcement’s sales transaction records, even those that do not identify the companies, are not public.

Marijuana industry representatives met with the division’s regulators late last month to push for a more aggressive response to the agency’s hemp replacement, even though it could affect some companies in the industry. The representatives argued that bad actors are unfairly driving down prices and shifting the tax burden to manufacturers and growers who are trying to comply with the rules. The newsletter was released a couple of weeks after that meeting.

“The division is also considering additional changes to its testing and screening protocols” to detect illegal products and prohibited methods, and may require additional laboratory tests “if needed for products throughout the supply chain,” the agency’s bulletin said.

This article was produced in partnership with ProPublica’s Local Reporting Network Denver Magazine. Sign up for Submissions to receive stories in your inbox every week.

user photo WeedPornDaily.

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Nascent medical cannabis industry aims for growth

Published

2 days ago

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April 18, 2026

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The medicinal cannabis sector is struggling to take root, and another specialist processing plant is set to close. But with current regulations and a new collective industry in mind, New Zealanders are promising to reduce their reliance on imported medicinals.

There was great excitement when medicinal cannabis was legalized and then regulated in 2020, with the hope of growing the domestic sector and serving patients here and abroad. However, since then, several companies have closed their doors, including Greenfern Industries, Cannasouth and, most recently, Helius Therapeutics.

The latter plans to close the East Tāmaki plant, affecting 65 workers. It is one of the few medicinal cannabis factories in the entire nation that has a specialized processing certificate called “Good Manufacturing Practice” (GMP).

Medical Cannabis Council executive director Sally King said that under current rules, most growers did not have such certification, and could only sell raw ingredients, not processed products such as more profitable cannabis capsules.

Read more at the town










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