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The Rise of Marijuana Creams and Salves

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Marijuana is a plant that has been cultivated for more than 4000 years. The first consumers and growers were mostly indigenous tribes, and its use is associated with medicinal, cultural and spiritual aspects. This ancestral and cultural wisdom has been passed down through generations, and knowledge has been shared in diverse communities for many years. However, prohibition and legal challenges have limited the dissemination of this knowledge and, in some cases, made it an illegal activity.

In the 1960s, the United Nations Single Convention on Narcotic Drugs classified marijuana at the same level of danger as heroin. However, in 2019, following the recommendations of the World Health Organization, the UN recognized the medical and therapeutic benefits of marijuana derivatives, and 27 countries voted to remove it from the list, where it had been alongside highly addictive and deadly opioids. This has important implications for the Colombian government, as it could lose the opportunity to participate in a lucrative legal market estimated at $146 billion by 2025, in addition to reducing smuggling and micro-trafficking caused by its illegality.

In recent years, sales of ancestral coca- and marijuana-based products in local markets and galleries have increased significantly due to their efficacy. However, these sales remain relatively discrete compared to other markets.

In Colombia’s marketplaces, it is common to find stalls openly selling these products, such as marijuana creams and ointments with mint, drops for wounds, or even toothpastes made with marijuana. There are also pills and liquids based on this plant for medicinal and spiritual purposes, since bad energies are also considered to be the cause of illness.

Nancy Fernández, a street vendor in the sector, explains that the sale of these products is common in marketplaces: “In any respectable Colombian market, you will find a stall selling the typical hot ointment, which is in great demand to quickly relieve cramps and pain. Many people buy it without fear, even though these products are not legal”.

Nancy points out that consumers trust the effectiveness and quality of these products. Despite their illegality, she has not had any problems with the authorities and the products are openly displayed in her stall. Customers often have preferences by brand and type, as some products are made with menthol and marijuana, others with coca, mint and marijuana, and others with marijuana, spearmint and mint, all for medicinal purposes.

Many of the products sold in these plazas are imported, as Victor Rentería, a merchant who supplies products to small stores, points out: “Most of the creams and ointments I sell wholesale come from abroad, mostly from Peru, Bolivia or Ecuador, where these marijuana-based products are freely marketed. We, who could produce them locally, do not have the necessary permits,” he says.

 

Efficacy in various green products

The efficacy of several products made with this plant is remarkable. Although marijuana ointment is better known commercially, there are other products that are equally effective. Nancy explains: “Besides the hot salve, there are other products made with marijuana, such as drops used to treat wounds and skin infections. There are also coca and marijuana-based creams for skin allergies, all with significant benefits and immediate action”.

The growing use of these products has strengthened the cannabis culture in the country. Its efficacy has allowed the creation of medicines to combat diseases caused by spiritual evils, as many indigenous cultures believe that diseases can also be the result of bad energies. Victor Rentería affirms that these ailments can be cured with spiritual remedies made with marijuana-based ingredients. “In addition to marketing marijuana creams and ointments, I also sell water made with herbs and marijuana. These are used to eliminate dark energy that is affecting a person, causing pain, bad luck, or bondage. These waters are requested with a prescription from the healer or monk who will expel the energy,” the merchant concludes.

In Latin America, several countries have legalized marijuana for medicinal use, including Argentina, Chile, Colombia, Mexico and Peru. Despite this, Colombia faces challenges in its industry, as there is no significant local production and no medicines based on Colombian cannabis have been developed. However, there is a growing political debate to allow the production and commercialization of Colombian cannabis in a free manner, allowing for its full recreational and medicinal legalization.



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Acne And CBD: Exploring Alternative Dermatological Solutions

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Cannabidiol (CBD) has been praised many times for its beneficial therapeutic properties. But does its effectiveness extend to dermatological conditions? Specifically, how does CBD help with acne? As acne remains one of the most common skin issues affecting millions worldwide, the quest for effective treatments is ever-present, and the exploration of cannabis in this domain is gaining momentum.

Due to its low likelihood of side effects, CBD may prove to be a relatively safe treatment, rightfully deserving the attention of scientists and dermatologists alike. As the stigma surrounding cannabis continues to fade, more researchers are investigating how its compounds, particularly CBD, can be harnessed for therapeutic benefits beyond recreational use.

The Science Behind CBD and Acne

Professor Attila Olah’s 2014 paper, published in the Journal of Clinical Investigation, provides compelling evidence that CBD has the potential to treat acne. The study found that cannabidiol exhibits lipostatic, anticancer, and anti-inflammatory properties. This is particularly relevant for those suffering from acne, as inflammation plays a critical role in its development.

lipophilic cannabinoids

Furthermore, the same study showed that Cannabidiol can stop the proliferation of sebocytes, the grease-producing cells of the sebaceous glands. While Cannabidiol does not cause existing sebocytes to die off, it significantly reduces their reproduction. By curbing the overproduction of sebum, one of the leading causes of acne, CBD offers a promising alternative to conventional treatments that often come with a host of side effects.

Moreover, Cannabidiol’s universal anti-inflammatory effect helps reduce the inflammation associated with acne, providing relief to those who experience painful cystic acne or inflamed lesions. This dual action of reducing sebum production and inflammation makes CBD a compelling candidate for acne treatment, and for its potential for many others medical applications as well.

Complementary Research on Phytocannabinoids

A 2016 report published in Experimental Dermatology complemented this research by analyzing the effects of other phytocannabinoids on acne. Researchers found that phytocannabinoids such as CBD, CBC, CBDV, and THCV may prove to be “new effective and safe agents against skin inflammation.” This broadens the scope of cannabis’ potential in skincare, suggesting that other compounds may also contribute to treatment efficacy.

In another fascinating study, patients applied a cream containing 3% cannabis seed extract twice a day for 12 weeks. Remarkably, the treatment led to a significant reduction in sebum secretion and redness, further underscoring the anti-acne properties of cannabis derivatives. Such findings point towards the therapeutic promise of cannabis-based skincare products, which may offer a more natural alternative to traditional treatments.

Ongoing Clinical Trials and Future Implications

Lastly, a synthetic CBD formulation for external use, known as BTX 1503, showed promising results when tested on volunteers. Its effectiveness is currently being evaluated in a randomized, double-blind clinical trial, which could pave the way for new, scientifically-backed treatments. The potential to provide an effective, low-side-effect solution for acne could transform the approach to skincare, especially for those seeking alternatives to harsher chemical treatments.

Conclusion

As research into the therapeutic benefits of cannabis continues to evolve, the potential of CBD in treating acne is becoming increasingly apparent. With its anti-inflammatory properties and ability to regulate sebum production, cannabidiol represents a safe and promising avenue for those struggling with this prevalent skin condition.

As we await further clinical studies and advancements in cannabis-based skincare, individuals interested in exploring CBD for acne treatment should consult with healthcare professionals to ensure a safe and informed approach.

Disclaimer: This content is meant for educational purposes only. It has been compiled with research from external sources. It is not meant to substitute any medical or legal advice. Please see your local laws for the legality of cannabis use and make sure you are under medical professional supervision when applying this knowledge.

FREQUENTLY ASKED QUESTIONS (FAQ)

How can cannabis seeds help with acne?

Cannabis seeds can be a starting point for cultivating plants that produce CBD, which has been shown to help with acne. CBD reduces the proliferation of sebocytes, the grease-producing cells in the sebaceous glands, and its anti-inflammatory properties help reduce the redness and swelling associated with acne. However, always consult with a healthcare professional before starting any new treatment.

Are there other cannabinoids from cannabis seeds that can aid in acne treatment?

Yes, besides CBD, other cannabinoids such as CBC, CBDV, and THCV, which can be derived from cannabis seeds, have shown potential in treating acne. Research indicates these compounds might serve as effective and safe agents against skin inflammation. Growing the right strains can provide a variety of these beneficial cannabinoids.

Is it safe to use products derived from cannabis seeds for acne treatment?

Products derived from cannabis seeds, particularly those high in CBD, are generally considered safe due to their low likelihood of side effects. However, it’s crucial to consult with a healthcare professional before using any cannabis-based treatment, especially if you have sensitive skin or are taking other medications. Always ensure that any treatment is supervised by a medical professional.



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What’s Next For Legal Marijuana

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Going into 2025,  the cannabis industry will have to be more limber. 

The election is done and Donald Trump will be returning to the White House and Republicans having greater control in Congress. The election showed the majority of people want recreational in Florida, Nebraska will finally have medical marijuana, and cannabis wasn’t a deciding factor in swinging votes. With the House firmly in Republican hands, Mike Johnson has greater power to battle legal cannabis, but don’t count the industry out yet.

Nebraska, passed two ballot initiatives to legalize medical marijuana and regulate the industry on Tuesday. A whopping 67% of the public said yes, which is great for a traditional lyconservative state.  Nebraska was one of the few holdouts for medical marijuana. The legality of the ballot initiatives is being questioned regarding discrepancy over fraudulent signatures and fraudulent notarizations. It is a civil case with a ruling expected after the election is cleared up. The Governor spoke out against cannabis. Those arguing on behalf of the petitioners said there was no “clear and convincing evidence” of fraud, and throwing out entire petitions would punish thousands of Nebraskan voters. If the cannabis backers and voters win the civil suit, medical marijuana should start by the end of 2025.

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While the initiative failed to reach the 60% of votes needed in Florida, it garnered an impressive 56% of public support. Showing the population of the sunshine state is for fully legal weed, but could be 4 years until it is available. There are issues are Governor DeSantis use of public assets to combat the issue, so my legal wrangling in Florida.

A portion of the industry supported the incoming president, but the biggest industry influence for the upcoming administration will be alcohol and pharmaceutical companies.  Alcohol alone is probably one of the biggest investors in the industry with over $13 billion. Wana Brands, which is partial owned by Constellation, launched hemp gummies that can be sold in most states and are as effective as THC gummies. A smart expansion of their products.

Cannabis is popular with the public with Pew Research saying 88+% of the population supporting legalization in some form.  Even the traditional AARP has come around to extoll the medical and wellness benefits of the plant.  A clearer pathway will be laid out in December with the DEA rescheduling.



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How Cannabis Helps With A Good Mood

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There is lots going on in the world…but marijuana may be able to lift your spirits.

Back to the office, weather, politics, Karens, all taking a bite of your spirits. Over 50% of Gen Z feels anxiety, While it looks like it can be a rough autumn, there is hope. Some are born with a set of genetic variants making it easier to feel happy, while others are less fortunate. Genetic variants also play a role in an individual’s responsiveness to the environment. Some need a little more help, be it music, pets, or more. Here is how cannabis helps with a good mood.

RELATED: Science Says Medical Marijuana Improves Quality Of Life

Cannabis has gained popularity not only for its recreational use but also for its potential mood-enhancing effects. The science behind cannabis’s ability to influence mood is complex and multifaceted, involving various chemical compounds and their interactions with the human brain and body. At the heart of cannabis’s mood-altering effects is the endocannabinoid system (ECS), a complex network of receptors and neurotransmitters found throughout the body. The ECS plays a crucial role in regulating various physiological processes, including mood, appetite, and pain sensation.

Ancient Chinese Tomb Shows Evidence Of Cannabis Use
Photo by CRYSTALWEED cannabis via Unsplash

The two main compounds of make the difference. First is THC (Tetrahydrocannabinol). This is the primary psychoactive compound in cannabis. It binds to cannabinoid receptors in the brain, particularly in areas associated with pleasure, memory, and cognition. By stimulating these receptors, THC can induce feelings of euphoria and relaxation. The other is CBD (Cannabidiol). Unlike THC, CBD is non-psychoactive but still interacts with the ECS. It has been shown to have anxiolytic (anti-anxiety) properties, which may contribute to improved mood.

Another path to helping is cannabis compounds can influence the release and reuptake of various neurotransmitters. Those including

Dopamine: THC can increase dopamine release in the brain’s reward centers, leading to feelings of pleasure and euphoria.

Serotonin: CBD may enhance serotonin signaling, which is associated with mood regulation and anxiety reduction.

GABA: Cannabis can affect GABA signaling, potentially promoting relaxation and stress relief.

.The anxiolytic effects of certain cannabis compounds, particularly CBD, may help reduce stress and promote a sense of calm. This stress-reducing effect can contribute to an overall improvement in mood.

RELATED: Couples Using Cannabis Can Increase Intimacy

It’s important to note that the mood-enhancing effects of cannabis are often dose-dependent. Lower doses tend to have antidepressant and anxiolytic effects, while higher doses may increase the risk of anxiety or paranoia.



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