Cannabis terpenes are responsible for each strain’s unique aroma. These cannabis compounds have particular scents that combine with other terpene aromas to create a one-of-a-kind scent profile. Bisabolol is a minor cannabinoid, but it may have significant therapeutic potential.
What Is the Bisabolol Terpene?
Bisabolol, also known as alpha-bisabolol and levomenol, is a sesquiterpene with a subtle floral aroma found in the cannabis plant, sage, the Candeia tree, and chamomile. Bisabolol is commonly used as an ingredient in skincare and cosmetic products.
Bisabolol is a secondary terpene found in small amounts in the cannabis plant. Primary terpenes such as myrcene, limonene, beta-caryophyllene, alpha-pinene, and more are found in higher amounts in the plant. Secondary terpenes are not as commonly found in cannabis.
Fast Facts: Alpha-bisabolol
Sweet floral aroma
Anti-inflammatory
Anti-irritant
Antioxidant
Anti-anxiety
Anti-pain
Antimicrobial
Gastro-protective
Bisabolol Aroma
While bisabolol is only found in small concentrations in some cannabis strains, some seasoned users may be able to detect its unique and subtle aroma. Bisabolol has a sweet floral scent. This terpene’s floral aroma may include nutty, herbal, and peppery notes.
Bisabolol Effects
Bisabolol may do more than give your favorite strain a floral aroma. Several experiments on animal models suggest that bisabolol may have a number of health benefits. More research is needed into its effects on the human mind and body.
Anti-Inflammatory
Bisabolol is known for its anti-inflammatory effects. In a 2014 study on cell cultures and live mice, researchers found that the alpha-bisabolol terpene slowed down the production of pro-inflammatory compounds known as cytokines. Bisabolol was also found to reduce skin inflammation in mice without side effects.
Antimicrobial
In a 2018 study, researchers reviewed the wound healing and nociceptive (pain sensitivity) properties of alpha-bisabolol from Candeia, a Brazilian tree with a high concentration of this terpene.
Bisabolol is thought to promote wound healing due to its anti-inflammatory, antifungal, and antibacterial properties. Bisabolol (chamomile oil) has also been used as an ingredient in wound dressings due to its antimicrobial effects.
Analgesic
The bisabolol terpene has been shown to provide pain relief. In a 2011 study, researchers discovered its analgesic properties when evaluating the effects of bisabolol on mice with paw edema. Research suggests that bisabolol lowered pain levels via its anti-inflammatory properties.
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Gastro-Protective
Some research has shown that bisabolol may have gastro-protective effects. In a 2018 study on rats, researchers found that alpha-bisabolol combined with diclofenac, an NSAID, provided synergistic effects.
Best of all, alpha-bisabolol reduced the risk of gastric damage, one of the most common adverse effects of taking diclofenac and other anti-inflammatory drugs. Diclofenac and bisabolol may be a safer treatment alternative than diclofenac alone.
Anxiolytic
In a 2017 study, researchers evaluated the behavioral effects of high doses of bisabolol on mice. Researchers found that the bisabolol terpene reduced anxious behavior. They believe bisabolol affected gamma-aminobutyric acid (GABA) receptors, known for producing a calming effect and helping provide relief for anxiety and stress.
High Bisabolol Cannabis Strains
Looking for bisabolol-rich marijuana strains? Bisabolol is found in various cannabis strains. If you want to experience its calming effects, give these cannabis strains a try:
Harle-Tsu
ACDC
Pink Kush
Master Kush
Headband
Sour Candy
Moonshine Haze
OG Shark
Rockstar
Dolato
Ice Cream Cake
Hawaiian Haze
Killer Queen
Grape Pie
Midnight
Chocolate Thai
Jasmine
Lavender
FAQs About Bisabolol Terpene
Where Does Bisabolol Come From?
Alpha-bisabolol was first reported as an active compound of German chamomile in the 1950s. Bisabolol is one of the primary compounds found in chamomile essential oil. Bisabolol can also be found in the Brazilian Candeia tree, South African candela tree, sage, and the cannabis plant.
Is Bisabolol Safe?
The Food and Drug Administration (FDA) states that bisabolol is “Generally Recognized as Safe” (GRAS). Bisabolol does not have any severe health risks or adverse effects. Speak with your doctor before using bisabolol to treat any medical condition.
Is Bisabolol Good for Skin?
Bisabolol has been known to provide relief for a range of skin conditions. Bisabolol is commonly used in skincare products due to its pleasant aroma and health benefits. This terpene ameliorates skin inflammation, reduces skin irritation, helps other compounds absorb better into the skin, and promotes wound healing.
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Is Bisabolol Psychoactive?
Technically, bisabolol does have psychoactive properties but is non-intoxicating. Psychoactivity describes any substance that affects the mind. Bisabolol can affect the mind by providing relaxing effects.
Final Thoughts on Bisabolol Terpenes
Bisabolol is a relatively unknown cannabis terpene compared to heavyweights like myrcene and beta-caryophyllene, but it can be found in many cannabis strains in low concentrations. Despite its obscurity, some research has shown that it has antimicrobial, anti-inflammatory, anti-pain, anti-anxiety, and wound headline characteristics.
Bisabolol’s effects have made it a popular ingredient in the skincare and cosmetics industry. It may also help reduce the side effects of anti-inflammatory medications. Bisabolol can be found in various strains and is also used as an isolate that can be blended with other essential oils.
When Colorado became the first state to legalize cannabis, Washington quickly followed suit. At this time, entrepreneurs had big dreams. Tales of a magical lounge where people could light up, and a cannabis wellness center that infused the plant into yoga and massage flowed through conversations about what could come next for weed.
Federally funded medical research reveals marijuana not tied to autism.
Drinking, smoking and consuming marijuana while pregnant is never recommended. Over the course of history, woman have consumed liquor, especially during the period when clean water was hard to find, but child mortality was high. With advances in medicine, it has been discovered some activities, like drinking and smoking cigarettes, can cause harm to the baby. No one is saying expectant women should have booze, buds, or cigarettes. But early on, when a woman doesn’t know she is expecting, she might have engaged in these habits
One of the concerns circling around cannabis is how it can affect a baby’s development. While more research needs to be done, two new studies have been published in the Journal of the American Medical Association (JAMA) which provides some good news. The first study focused on discovering if maternal cannabis use during early pregnancy associated with risk of child autism spectrum disorder (ASD).
This study included 178 948 mother-child combinations. The children were born between 2011 and 2019 to pregnant Kaiser Permanente Northern California members screened for prenatal cannabis use during pregnancy. Statistical analysis was conducted February 2023 to March 2024. The findings suggest maternal cannabis use during early pregnancy was not associated with child ASD, but additional research should be conducted to replicate the findings.
Another study released this week found maternal cannabis use during early pregnancy was not associated with speech and language disorders, global delay, or motor delay. The investigation into marijuana and childhood development and included 119 976 pregnancies among 106 240 unique pregnant individuals.
A reason for the study is with legal marijuana increased, this is increased discussion around it being a cause of developmental development among babies. But documented associations between maternal prenatal cannabis use and adverse birth outcomes, including preterm birth and low birthweight have not be in a study. There has been little research assessing the association of maternal prenatal cannabis use and childhood developmental outcomes, this study was done to provide a scientific fact around the information.
More research needs to be done, and like alcohol and cigarettes which are harmful for the body, not one is saying it is good to use why expecting, but it is good to have information grounded in facts.
The U.S. government recently proposed rescheduling cannabis from a Schedule I to a Schedule III drug (https://www.dea.gov/drug-information/…) — basically signaling it has some accepted medical use and a moderate to low potential for physical and psychological dependence. But what does this mean in the real world exactly? Sanjay talks with “The Pot Doc” Dr. Staci Gruber (https://www.drstacigruber.com/) , Director of the Marijuana Investigations for Neuroscientific Discovery (MIND) program in Boston, to explore the possible impacts of this rescheduling on research, healthcare, and yes – even you.