American College of Physicians

Is CBN Right For You

Published

3 months ago

September 4, 2024

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Sitting at the crossroads of THC and CBD – CBD helps with sleep and pain. Could it be right for you?

Marijuana is been proven a benefit to the medical world and the American Medical Association, Health and Human Services, the American College of Physicians and the Food and Drug administration all support increasing it’s reach and for more research. It has been shown to be particularly helpful with chronic pain, nausea, and sleep. The cannabis plant provide a variety of cannabinols, including CBD, marijuana and CBN. But the medical question is CBN right for you? It sits at the crossroads between CBD and THC can be useful with health issues.

Like CBD and THC, CBN is among the 100+ molecules in the cannabis plant. When THC is heated and exposed to CO2 (oxygen), it converts to CBN. The compound is said to have a mild psychoactive effect, slightly more so than CBD but much less than THC. Specifically, it is said to have a sedating effect on most users and to have promising sleep aid applications, similar to melatonin (among other potential uses).

How Marijuana's THCV Can Positively Impact Your Life — Photo by Bacsica/Getty Images

The marketing of CBN as a dietary supplement may be viable, provided that no unapproved health claims are made and could be nationally legal as long as they have a THC concentration of 0.3% or less. Unlike CBN and like THC, CBN is legal in some states, but not federally. The FDA likes to point out that the 2018 Farm Bill explicitly preserved FDA’s authority to regulate products containing cannabis or cannabis-derived compounds under the Food Drug & Cosmetic Act (“FDCA”) and section 351 of the Public Health Service Act. But the marketing of CBN as a dietary supplement may be viable nonetheless, provided that no unapproved health claims are made.

RELATED: What Is CBG And Is It Legal?

Unlike CBD, CBN not been approved as a drug, and FDA itself has acknowledged “parts of the cannabis plant that do not contain THC or CBD might fall outside the scope of the [drug exclusion rule].” As with CBG, if CBN is approved as a drug at some point down the line, it also seems likely that the drug exclusion rule would not apply: this is because the rule contains an exception for substances marketed as foods or dietary supplements prior to any FDA clinical investigation. People are already marketing CBN products as foods and dietary supplements.

But the question is still, is CBN right for you? With regards to sleep, it is can be a bit stronger than CBD alone. While melatonin is a known as a good over the counter sleep aid, it doesn’t work for everyone.

A clinical study looked into sleep improvements from 15 mg of CBD with or without 15 mg of CBN compared with 5 mg of melatonin. In the study, all groups reported improved sleep quality, and there were no significant differences between products. Since this study didn’t look at CBN alone, it isn’t a direct comparison. But it seems to indicate that products containing an equal amount of CBD and CBN are similarly effective to melatonin for sleep. And adding a CBD/CBN product to melatonin didn’t provide any added benefit.

CBN use showed relief in muscle and joint pain conditions with inflammation. Limited studies show The study also noted that pain relief was better when CBD and CBN were used together.

So CBN can be helpful if you need a little extra in over the counter help.

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AARP

How Cannabis Can Help With Dysmenorrhea

Published

2 weeks ago

November 9, 2024

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Millions suffer, but relief could be here thanks to science and a simple plant. Here is how cannabis can help with dysmenorrhea.

It is an uncomfortable topic to discuss, but the painful truth is a majority of women will suffer it at some point and finding relief is invaluable. Around 80% of women experience period pain at some stage in their lifetime. Dysmenorrhea is the medical term for pain or discomfort during menstruation. It is a common gynecologic problem, but the pain can range from dull cramps to indescribable agony. Here is how cannabis can help with dysmenorrhea.

Medicinal cannabis has emerged as a potential treatment option for dysmenorrhea, offering hope for the tens of millions of women who suffer from menstrual pain. Current medical management options primarily consisting of over-the-counter pain relievers and hormonal contraceptives. The effectiveness of these treatments vary greatly.

The endocannabinoid system plays a role in uterine function and pain perception. Cannabinoid receptors CB1R and CB2R, as well as TRPV receptors, have been identified in human myometrial tissue. Tetrahydrocannabinol (THC), a primary component of cannabis, can act as a cannabinoid agonist, potentially triggering myometrial relaxation and easing menstrual pain.

The potential benefits of cannabis for dysmenorrhea includes pain relief, improved sleep quality, and reduced reliance on pharmaceutical pain relievers. While research specifically on cannabis for dysmenorrhea is growing, studies on chronic pain provide some insights:

A systematic review of 18 randomized controlled trials found that synthetic cannabis products with high THC-to-CBD ratios may offer moderate improvement in pain severity.
A meta-analysis of 32 trials showed that medical cannabis or cannabinoids resulted in small to very small improvements in pain relief, physical functioning, and sleep quality among chronic pain patients.

There is significant interest in using cannabis for gynecologic pain management:

A survey found that 61.2% of women who had never used cannabis and 90.0% of those who had were willing to try it for gynecologic pain.
After cannabis legalization in Canada, current cannabis use increased from 13.3% to 21.5% among women with self-reported moderate-to-severe pelvic pain.

With th American Medical Association, American College of Physicians and even AARP recognizing the medical benefits of cannabis, it is critical more research is funded. Millions of women may be in pain needlessly due to untreated dysmenorrhea.

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American College of Physicians

New Data About Cancer And Cannabis

Published

2 months ago

September 23, 2024

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While there is a need for more research, the data has good news.

The American Medical Association and the American College of Physicians along with the federal agencies Health and Human Services (HHS) and the Food and Drug Administration (FDA) have all spoke up about the need for additional research to unlock medical benefits of cannabis. The acknowledge it can help, but need more information, including more understand about dosage. Now, a study reveals more data about cancer and cannabis which only reenforces their call to action.

While cannabis is not a treatment for cancer, studies support marijuana-derived cannabinoids. TCH and CBD can help relieve symptoms and ease the side effects of cancer, including chemotherapy. More research can be done on treatment, but how do patients feel about using medical marijuana? The University of California San Diego and VA Health Care researchers partners for the one-year study. Team conducted a comprehensive survey of nearly 1,000 adult cancer patients at various stages of cancer treatment. What they discovered wasn’t a common sense surprise.

The lead researchers Corinne McDaniels-Davidson’s published in the Journal of the National Cancer Institute. They explored the decision-making process, perceived benefits, and risks of cannabis use to address symptoms in adults with cancer.

“There’s a vacuum in the world of cancer care. Many oncologists don’t talk to their patients about cannabis or refer them to a pain management specialist instead,” said McDaniels-Davidson, who is the associate director at the SDSU School of Public Health.

“Our data shows about a third of the patients surveyed used cannabis after their diagnosis, but only a few of those patients said they had told their oncologist,” said McDaniels-Davidson.

Cannabis has been used as medicine for thousands of years. The archeological site in the Oki Islands near Japan contained cannabis achenes from about 8000 BC, but it developed a bad name in the early 20th century. But the understanding it works is still strong. Survivors who perceived cannabis had any benefits were five times more likely to use it. Those who perceived there were any risks were nearly 60% less likely to have used it post-diagnosis.

According to the study, cancer survivors diagnosed with stage 3 or 4 were also more likely to use cannabis. Among those who used cannabis, 19% said they believed the misconception that it could treat or cure cancer. Cannabis can not cure cancer, a fact which needs to be made clear, but it increasing can help treat the disease. This study gives medical professional another tool to talk with patients.

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Administration

Biden Administration Puts A Knife Into The Cannabis Industry

Published

3 months ago

August 30, 2024

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In surprise to no one considering the history of the administration leaders, Biden administration starts to wind down legal marijuana

Mom and pop businesses have been struggling the last 2 years. Thousands are in hte cannabis business, many having the hope from the Biden/Harris 2020 campaign about helping them. Almost 4 years later, there has been no change, and while marijuana use soars, federal government are putting hundreds of businesses out even in fully legal states. The DEA action is paving the way for a robust illegal market.

Has Biden administration killed put a knife into the cannabis industry. Has former foe of cannabis managed to effectively put a stop to the legal cannabis industry? Biden has been in the federal government for 51 years. His tenure has given him unique insight in how government works, the timeline and how to move projects forward. Until recently, Biden and Harris were anti-marijuana, but recognizing the direction of voters, especially younger voters, they made a pivot. But was it a move to try to engage the youth movement without having to deliver a final product? The announcement by the Drug Enforcement Administration to delay until at least 2 December has thrown the industry into a tailspin with stocks dropping due to the announcement.

Biden is quick to comment “Don’t tell me what you value. Show me your budget, and I’ll tell you what you value.” In 2020 the Biden/Harris ticket promised to help the industry by readdressing cannabis. But in reality, Biden waited over 3 years before he made the move. An experienced lawmaker understands the wheels of change moves slowly. Especially when the an agency like the DEA is resistant to the change. The timing of the start to reschedule cannabis allows the campaign to say “look what we are doing”, but actual change may or may not happen. In reality, Biden told the public he values cannabis, but he didn’t put a true push on an easy change until months before the end of his term. Most likely knowing the clock would run out. It is disappointing as the Veterans Administration acknowledged it is an important option for veterans, especially with those with PTSD.

Anne Milligan, is the administrator of the DEA and was appointed by the current administration. The DEA is a federal agency overseen by the presidential administration and has made it clear it is not onboard with 85+% of the population’s view on cannabis. It has also not been pleased Health and Human Services (HHS), The American Medical Association, Canada, the Food and Drug Administration and the American College of Physicians have all recommended rescheduling based on the science behind the plant’s medical benefits

Has the Biden administration pulled a bait and switch

The industry is full of mom and pop organizations who are trying to help build a new economic engine. Gen Z, understanding marijuana is healthy than alcohol, has embraced weed and beer sales have been down. Consumer use has soared among all age groups. Legal states have been reaping the economic benefits, but the DEA doesn’t seemed to be phased by the change of the public acceptance.

While Harris drinks alcohol, Biden and the GOP presidential nominee do not. Harris and Biden have a history of being strong legal cannabis foes. On the campaign trail, Harris seems to support the industry, but has done nothing publicly or via government regulations to help the small businesses in the sector.

Both Harris and Biden are seasoned policy markers, so it would come as no surprise the timeline or the announcement. Harris has revitalized part of the Democrat campaign with other opportunities to engage younger voters. Has the current administration pulled another bait and switch with the industry?

Should the Harris team lose, it gives House Speaker Mike Johnson a chance to end legal marijuana also. He is dead set against any form of legalization. Some leaders in the industry have doubts about the Biden/Harris take on marijuana and have been expanding into hemp, which Senator Mitch McConnell championed. So like another president, Gerald Ford when NYC was in trouble, Biden sent a very clear message to the industry.

Biden Administration Puts A Knife Into The Cannabis Industry