Cannabis

A Look At Cannabinoid Hyperemesis Syndrome

Published

11 months ago

March 7, 2024

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Activation of neurological cannabinoid receptors can aid in preventing nausea and vomiting, particularly so in patients undergoing chemotherapy. Considering the usual effects of THC and other cannabinoids on receptors in the brain, cannabinoid hyperemesis syndrome (CHS) seems to be a paradoxical condition. So why do some individuals suffer from this syndrome?

First described in 2004, CHS typically affects long term consumers of cannabis more so than casual users. It is a condition characterized by chronic cannabis use, cyclic episodes of nausea and vomiting, and excessive bathing or showering with hot water to abate the symptoms and to find relief. As more states legalize cannabis for medical and adult recreational use, emergency departments across the country are seeing a rise in the number of individuals diagnosed with Cannabinoid Hyperemesis Syndrome (CHS).

It has been proposed that receptors in the brain stop responding to cannabis in their usual manner in some individuals. Meanwhile, cannabinoid receptors in the gastrointestinal track that seem to have the opposite effects on nausea and vomiting are still activated. When this happens, gastrointestinal receptors that are no longer overshadowed by the effects of cannabis in the brain lead to abdominal discomfort, pain, and nausea.

CHS is divided into three stages; prodromal, hyperemetic, and recovery phases. In the prodromal phase, individuals may experience early morning nausea and abdominal pain, though most will continue with normal eating patterns. Some may increase their consumption of cannabis, seeking relief from the general discomfort. This phase is often misdiagnosed due to nonspecific symptoms and may last for months to years.

In the hyperemetic phase, individuals have continued nausea, multiple episodes of vomiting, increased abdominal pain, decreased food intake and weight loss, as well as dehydration. During this period, hot showers tend to alleviate the discomfort and nausea. This phase may continue until an individual completely discontinues use of cannabis. It usually takes one to two days for the hyperemetic phase to resolve.

Treatment is palliative in the hyperemetic phase as it takes time for the endocannabinoid system to return to an inactivated state. IV fluids are given to prevent or treat dehydration, antiemetics and proton pump inhibitors are given to decrease vomiting and nausea, as well as capsaicin cream applied to the stomach.¹ Finally, in the recovery phase an individual will begin to resume normal eating habits and will stop suffering from gastrointestinal issues. This phase may last days or weeks, however symptoms may come back upon use of cannabis.

It has been theorized that the recent uptick in cases of CHS may be due to the increased availability of high potency THC products.¹ However, a recent Canadian study indicates that other factors may be at play. Two groups were compared, one suffering from CHS, and one that consisted of cannabis users who were not. The study found there was not an obvious correlation between cannabinoid concentrations in individuals and CHS occurring.4 In any case, further research on the specific cannabinoids and receptors involved will be necessary to fully understand CHS moving forward.

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Cannabis

RFK Jr. Does Champion Cannabis

Published

30 minutes ago

January 30, 2025

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He is in middle of the process to be the new Health and Human Services Secretary, the good news he aligns with their stance on marijuana.

Robert F Kennedy, Jr has some unique healthcare ideas and it is causing a bit of a stir in Congress. He is being nominated to be the Secretary of the Department of Health and Human Services. The agency, among other things, is responsible for advancing the sciences underlying medicine, public health, and social services along with ensuring food and drug safety, and provide health insurance programs. Part of the programs they oversee include the Food and Drug Administration (FDA), the Centers for Disease Control and Prevention (CDC), and the National Institutes of Health (NIH). It is a massive job with million of lives effected. His approval by the Senate could make a difference in one area, RFK Jr does champion cannabis.

Kennedy has gained the ire of public health officials, the Kennedy family, bipartisan Congressional members and more…but the new administration backs him. When he announced his endorsement of this GOP nominees, the current President embraced him wholeheartedly. He would have influence of the chaos of the rescheduling process. He would also provide home to the thousands of small business in the industry.

Kennedy’s stance on marijuana is multifaceted:

Federal Legalization: He supports the complete federal legalization of marijuana, which would align federal policy with the growing number of states that have already legalized cannabis for recreational use.
Banking Services: Kennedy advocates for opening up traditional banking services to the cannabis industry. This would address the current cash-intensive nature of the business, which he believes encourages crime.
Tax Revenue Allocation: A central aspect of Kennedy’s plan is to implement a federal tax on marijuana sales. He proposes using this revenue specifically to fund drug treatment and rehabilitation centers.
Treatment Centers: Kennedy envisions creating “renewal centers” that would focus on treating mental illness, PTSD, and drug addiction. These centers would also incorporate therapeutic activities like organic farming.
Personal Freedom: While acknowledging his own past struggles with addiction, Kennedy emphasizes the importance of personal freedoms and views the current policy of criminalizing and incarcerating people for drug use as unsustainable.

As the debate around marijuana legalization continues, Kennedy’s stance represents a an updated and science based cannabis policy. It also emphasizes treatment and regulation over criminalization. His position aligns with a growing bipartisan trend towards cannabis legalization, reflecting changing public attitudes and a reevaluation of America’s approach to drug policy

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AI

How AI Impacts The Cannabis Industry

Published

1 day ago

January 29, 2025

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Artificial Intelligence has been the shiny new toy and now has hit a threat….but has it had an impact on the cannabis industry?

The Chinese companies DeepSeek and Alibaba have upended artificial intelligence (AI) world this week. AI has been the new buzz world and an investment darling, raking in billions with the promise of a changed world. Amazon, Microsoft, Meta, Oracle, and more have worked to integrate into their businesses in the pursuit of more innovations, effectiveness and cost saving business lines. ChatGPT rocked the world and Nvidia become the darling of Wall Street. But this week, analysts had a chance to review DeepSeek and it sent the US AI market spiraling…causes a dip in the stock market. Here is how AI impacts the cannabis industry.

One of the downsides of this new technology is how venture firms have become hyper-focused on tech, specifically AI. When companies announce AI they get a stock boost and it is popping up in a variety of places from phones to appliances. The entry of DeepSeek could be a devastating event for venture capital firms who went all-in on foundational model companies. The amount of capital is much more than anything firms has ever before disbursed, based on what might be a suddenly-stale thesis. Now they could be in danger.

Despite the financial aspect, AI is helping the cannabis industry. It is having the biggest impact in various aspects of cultivation, production, and retail. This technological advancement is enhancing efficiency, quality, and sustainability across the entire cannabis supply chain.In cultivation, AI algorithms are optimizing growth conditions by processing environmental and plant health data to maintain ideal growing conditions. This maximizes yield and reduces resource waste. AI-powered video analytics and machine learning technologies are providing detailed insights into every aspect of the growing process. These systems analyze data from environmental sensors and cameras to monitor conditions such as light, humidity, temperature, and CO2 levels in real-time, making precise adjustments to maintain optimal growing conditions.

AI systems are also optimizing water and nutrient delivery to cannabis plants, significantly affecting yields and product quality. By analyzing data from soil moisture and nutrient sensors, these systems precisely adjust irrigation and fertilization schedules based on the plants’ needs. This technology not only improves crop performance but also conserves resources and reduces environmental impact.

In the harvesting process, AI-driven robotics are automating and streamlining operations. These robots use AI video analytics to determine the optimal harvest time for each plant, ensuring consistent quality and reducing labor costs. Companies like Bloom Automation have developed robots that can delicately handle plants, identify ripe cannabis flowers, and trim buds from branches with precision.

In supply chain management, AI algorithms are optimizing inventory management, forecasting demand, and streamlining logistics. By analyzing sales data, production schedules, and market trends, AI helps businesses forecast demand, minimize excess inventory, and streamline distribution processes. This enhanced visibility and control over the supply chain empower cannabis businesses to make data-driven decisions and improve operational efficiency.

Moreover, predictive analytics can anticipate customer demand and optimize inventory management, ensuring that products are available when and where they are needed.

As AI continues to evolve, its impact on the cannabis industry is expected to grow, driving innovation, efficiency, and quality across all aspects of the sector. However, challenges such as high implementation costs for smaller companies and data privacy concerns will need to be addressed to fully realize AI’s potential in this rapidly growing industry. Also, the Chinese government have a worse aversion to cannabis than most companies, and it could impact customer perception in the future.

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Cannabis

The Best Marijuana Strains For Your Chinese Zodiac Sign

Published

2 days ago

January 29, 2025

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As we start the year of the snake – are you curious what cannabis strain is best for your sign?

Lunar New Year is a significant cultural festival celebrated by many Asian countries marking the beginning of a new year based on lunar or lunisolar calendars. It typically begins with the first new moon of the lunar calendar and lasts for 15 days, ending with the Lantern Festival. It is most important festival of the year for many Asian cultures. This year is the year of the snake! But why not skip the tradition of the red envelope and go straight for the green! Here are the best marijuana strains for your Chinese Zodiac sign.

Cannabis enthusiasts and astrology buffs alike have found an intriguing intersection between the lunar zodiac and marijuana strains. This fusion of ancient wisdom and modern horticulture has given rise to a unique way of selecting and experiencing cannabis based on one’s astrological sign.

Each zodiac sign is believed to have distinct traits that can be complemented by specific cannabis strains1. For instance, the bold and energetic Aries might find harmony with sativa-dominant strains like Green Crack or Jack Herer, which provide an uplifting and energizing experience13. In contrast, the grounded and sensual Taurus may prefer indica-leaning strains such as Grandaddy Purple or Northern Lights, known for their relaxing and indulgent effects. Here is what is best for you.

Rat: Known for intelligence and adaptability. Strain: Green Crack – energizing and mentally stimulating

Ox: Diligent and strong. Strain: OG Kush – relaxing and stress-relieving, perfect after a hard day’s work

Tiger: Brave and confident. Strain: Sour Diesel – energizing and confidence-boosting

Rabbit: Gentle and elegant. Strain: Harlequin – calming with high CBD content for anxiety relief

Dragon: Charismatic and energetic. Strain: Durban Poison – uplifting and creative

Snake: Wise and enigmatic. Strain: Girl Scout Cookies – balanced hybrid for introspection

Horse: Energetic and free-spirited. Strain: Jack Herer – energizing sativa for adventure

Goat: Mild-mannered and creative. Strain: Blue Dream – relaxing yet creative-enhancing

Monkey: Clever and playful. Strain: Trainwreck – euphoric and sociable

Rooster: Observant and hardworking. Strain: Skywalker OG – relaxing without impairing productivity

Dog: Loyal and honest. Strain: ACDC – high CBD strain for gentle relaxation

Pig: Easy-going and generous. Strain: Purple Punch – deeply relaxing and comforting1.

The connection between astrology and cannabis extends beyond strain selection and cultivation. In some spiritual practices, such as Hoodoo, certain plants and animals associated with zodiac signs are believed to have magical properties6. This cultural overlap highlights the diverse ways in which astrology and plant medicine intersect across different traditions.

While often referred to as “Chinese New Year” in the United States, the term “Lunar New Year” is preferred by many Asian communities to recognize the broader cultural significance of the celebration

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