Researchers have developed a new class of CBD-like compounds that are even more effective in treating epilepsy and promote brain cell development. But instead of extracting cannabis from the plant, the scientists conducting the federally funded research used a common household spice: caraway seeds.
Psychology students and faculty at the University of Nevada, Las Vegas (UNLV) took the non-cannabis spice — commonly found in breads, stews, cheeses and more — and genetically engineered it to create compounds that resemble the molecular structure of the non-toxic CBD.
While this is a scientific feat in itself, the researchers are particularly pleased that these compounds, which have been shown to have a “bigger hole” than the natural cannabidiol found in the cannabis plant itself, provide a “bigger hole” using the hemp plant’s CBD.
“These fully synthetic compounds, made from a safe plant extract and free of THC, not only prevented seizures and reduced seizure-related deaths, but also promoted healthier brain cell development without the sedative side effects of current treatments,” Dustin Hines, study author and professor of neuroscience at UNLV, said in a press release.
“Childhood seizure disorders are often resistant to available medications, and both seizures and current first-line therapies can have a significant impact on brain development, cognition and quality of life, making this finding particularly promising,” he said. he said.
The to analyzePublished in the journal Neuropsychopharmacology late last month, it found that CBD synthesized from the seeds of cabbage, also known as meridian fennel, “significantly reduces seizure-related mortality in both C57Bl6 adults and a mouse model of developing epilepsy, supporting its potential for further preclinical and clinical development.”
The research was supported by grants from the National Institutes of Health (NIH), through NIH component agencies, the National Institute of General Medical Sciences and the National Institute of Neurological Disorders and Stroke.
As the authors emphasize, this is only the beginning of research into the medical potential of these new compounds, and they hope to develop new anti-epileptic therapeutics. There is currently one Food and Drug Administration (FDA)-approved CBD prescription drug, Epidiolex, derived from cannabis.
“The advancement of this new class of therapeutics holds great promise for patients who have exhausted existing treatment options due to debilitating side effects or lack of response to currently available therapies,” said Adriana Carrillo, a UNLV student who participated in the study.
“It’s exciting to help build the foundation for future treatment options that may one day provide safer and more effective options for families,” she said.
He also offered a tip for the curious: Caraway seeds don’t contain CBD on their own, so don’t expect to reap the benefits just by loading up on the spice, as the seeds are “just the scaffolding.”
Marijuana Moment is made possible with the help of readers. If you rely on our pro-cannabis journalism to stay informed, consider a monthly Patreon pledge.
GeoCue welcomes MOST Robotics to its global distribution network. Based in Germany and serving customers throughout Germany, Austria and Switzerland, MOST Robotics will offer TrueView GO LiDAR solutions and LP360 software, from GeoCue, to surveying, construction, forestry, agricultural and industrial inspection professionals looking for a complete and reliable workflow from data capture to delivery.
Founded in 2021 by Valentin Möller and Lennart Stollberg, MOST Robotics builds on deep UAV experience since 2015, offering integrated turnkey drone and sensor solutions, supported by technical consulting and first-class customer support. Their team works closely with end users to ensure technology works in real-world conditions, from flight planning to endpoint cloud processing, a full-service company for individual solutions.
MOST Robotics is expanding its portfolio of handheld SLAM LiDAR and LP360 software to directly respond to customer needs, especially for projects where flight restrictions, dense vegetation or indoor environments make aerial collection difficult. With TrueView GO and LP360, customers can complement drone surveys with ground-based SLAM capture, process aerial LiDAR and produce high-quality photogrammetric output. This approach supports rapid and accurate classification of large data sets and the creation of highly accurate digital terrain models, helping to reduce office processing time while improving the final quality of delivery.
Valentin Möller, CEO of MOST Robotics, commented: “GeoCue makes UAV LiDAR and SLAM bridges in a way that matches how our customers work in the real world. We spend a lot of time in the field with customers, which gives us practical feedback and clear ideas on what needs to be improved. GeoCue is open to this kind of input, and we’re excited to help shape each of our customers’ missions.”
Samuel Flick, GeoCue’s European Sales Manager, added: “We are delighted to welcome MOST Robotics to the GeoCue distribution network. Their technical depth and customer-first approach make them a strong partner as we continue to grow the LiDAR market in Europe. We look forward to supporting their team as they expand access to the TrueView product line, including aerial, handheld and LiDAR 360 mobile device software.”
USDA’s Animal and Plant Health Inspection Service (APHIS) recently issued regulatory status review responses for two new gene-edited hemp varieties, determining that they are not subject to federal regulation under 7 CFR part 340. Developed by researchers at the University of Wisconsin-Madison, these gene-edited plants have been found to have no increased risk of plant pests compared to conventional hemp. This federal clearance marks an important milestone in easing the path from laboratory to commercial cultivation of precision-bred industrial crops.
Badger PMR (Dust Resistant) has full dust resistance, and Badger Zero (Cannabinoid Free) is cannabinoid free. The main innovation involves the creation of hemp varieties that are unable to produce THC (tetrahydrocannabinol), the psychoactive compound found in cannabis. Using CRISPR gene-editing technology to turn off specific genes responsible for THC production, the UW-Madison team has solved a major hurdle for the industry. This genetic certainty prevents crops from being “hot” — the term used when THC levels accidentally exceed the legal limit of 0.3 percent — which previously forced farmers to destroy entire fields to comply with federal law.
Beyond THC removal, researchers have also engineered varieties with higher concentrations of CBG (cannabigerol), a non-psychoactive cannabinoid valued for its potential therapeutic benefits. These advances are expected to stabilize the hemp market, providing growers with reliable, high-value and legal-compliant varieties. With the regulatory green light from the USDA, these precision-bred hemp lines are poised to revitalize the industry, providing a safer and more profitable future for farmers across the United States.
For more information: International Service for the Acquisition of Agricultural Biotechnology Applications Email: (email protected) isaaa.org/default.asp
Kentucky’s governor is urging lawmakers to give more patients legal access to medical marijuana, announcing that cannabis gummies can now be purchased at state-licensed dispensaries.
Gov. Andy Beshear (D) said Thursday that his administration has sent a letter urging legislative leadership to pass a bill that lists ALS, Parkinson’s disease, Crohn’s disease, sickle cell anemia, fibromyalgia, glaucoma, terminal illnesses and other conditions as conditions for medical cannabis.
“In most other states that have a medical marijuana program, these are conditions that are covered, and conditions that are deemed appropriate by our board of physicians and counselors,” he said. “Expanding the list could help the approximately 430,000 Kentuckians who currently lack access but face these challenges.”
The governor said state officials are “making great strides” in expanding the medical marijuana program to “increase access for those who are already eligible.”
“We currently have 510 registered professionals and over 18,500 approved cards, and those numbers continue to grow,” Beshear said, adding that regulators are making “steady progress” in accepting businesses at every step of the cannabis supply chain.
“As the supply chain expands, patients are starting to see more options online,” he said. “We can announce that gummies are on the market in Kentucky and showing progress in communities across Kentucky.”
The governor, who has long championed cannabis reform, he anticipated a market launch that monthwhile claiming that medical marijuana will help thousands of patients find an alternative to opioids for pain management.
Beshear previously acknowledged that “it’s taken longer than we would have liked” to sustain the industry since he signed off on legalizing medical marijuana in 2023.
Beshear announced separately that in May the state launched a new online directory that allows people to see where medicinal cannabis will open next to them
Meanwhile, the governors sent a letter to Kentucky’s congressional delegation last yearurging them to “take decisive action to protect the constitutional rights of our law-abiding medical cannabis patients” by repealing the federal ban on possession of firearms by marijuana users.
The federal Bureau of Alcohol, Tobacco, Firearms and Explosives (ATF) warned Kentucky residents that in 2024, if they choose to participate in the state’s medical marijuana program, they will be prohibited from buying or possessing firearms under federal law.
Marihuana Moment is made possible with the help of readers. If you rely on our pro-cannabis journalism to stay informed, consider a monthly Patreon pledge.