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Can I Try Shrooms, Mom? – How to Talk to Your Kids about Psychedelics

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It could get into the hands of underage kids, which is why it’s up to parents to educate children on the use of psychedelics. The risk for kids accidentally being exposed to psychedelics is also largely because more parents are microdosing mushrooms and other psychedelic drugs – after all, we need to heal ourselves too. Teenagers may also be experimenting with mushrooms in place of marijuana or alcohol. While mushrooms are safer choices, it’s still not



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The Billion Dollar Psilocybin Patent Race

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Psychedelics Pending Patents: Can A Company Own Psilocybin Forever and Ever?

 

An interesting money grab is taking place in the psychedelics space as Cannabis.net first hinted at during their review of the Benzinga Psychedelics Conference in Miami.  They covered the general subject of how companies can make money in mushroooms and what is the homerun, retirement type money grab going on.  The subject is covered here in the article:

But wait, how is anyone going to get rich in psychedelics to begin with?  The big homerun pitch is in the creation of as many novel molecules as a company can create and then get a patent on them as soon as possible.  There are thousands of patents being sent in by early state psychedelic companies as part of a “molecule land grab” if you will, being that if you own the patent on XYZ novel molecule, and it later helps to reverse dementia in seniors, guess what?  You just bought yourself an island.

Smart money is setting up their companies in this manner in order to someday, fingers crossed, be bought by Big Pharma.  An IPO or sale to Big Pharma is the homerun, so having IP (intellectual property) many at experts feel is the key to a big payday down the road.  If your company has a patent on 4,000 novel molecules that need research, the odds are better one of them turns out to be medically miraculous, as opposed to a company that may have 500 novel molecule patents. These novel molecules, many with no research being done on them, are like little lottery tickets for these very small psychedelics companies. Enveric Biosciences is publicly traded and is aggressive in following this model.  Psychedelics also has an ETF, from AdvisorShares, the symbol is PSIL, for psilocybin.

 

Well, it seems that companies are trying to go for the trillion dollar home run itself, psilocybin!

 

The real crystal structures of medicinal psilocybin were revealed on December 20, 2021, thanks to ground-breaking research carried out by the Usona Institute, a 501(c)(3) non-profit medical research organization with its headquarters located in Madison, Wisconsin. This finding represents an important understanding of the innate traits of the plant’s polymorphs that had remained hidden up to this point.

 

However, this revelation has sparked a contentious debate within the psychedelics sector regarding the pursuit of synthetic psilocybin patents by Compass Pathways (NASDAQ: CMPS), a prominent player in psychedelics product development. They claim to have discovered essentially the same polymorph that the Usona research has now documented.

 

The recent study from the Usona Institute elucidated the experimental hurdles encountered in unraveling the crystallographic mystery of synthetic psilocybin, shedding light on the polymorphs, distinct crystalline structures naturally arising from synthetic psilocybin production.

 

Usona asserts that their study unequivocally demonstrates the recurrent occurrence of three psilocybin polymorphs resulting from the well-established crystallization process. These polymorphs have reportedly manifested across numerous instances in the history of psilocybin synthesis dating back to 1959.

 

In essence, the study posits that there are no groundbreaking findings to be gleaned from this research.

 

However, Compass Pathways holds a divergent viewpoint. The company claims to have pioneered polymorph A, the crystalline form of psilocybin utilized in their synthesized formulations, and is seeking to patent it. Yet, experts caution against hasty conclusions.

 

Navigating the Patent Dilemma

 

According to the Usona team of chemists and collaborating crystallographers, they have successfully deciphered crucial psilocybin crystal structures by analyzing powder X-ray diffraction (PXRD) data collected at the Advanced Photon Source synchrotron at Argonne National Laboratory.

 

During the course of Usona’s process-scale crystallographic investigation, three distinct crystalline forms of psilocybin were consistently observed: hydrate A, polymorph A, and polymorph B. While the crystal structure of hydrate A had previously been resolved using X-ray diffraction, Usona’s study introduces novel solutions for the crystal structures of the two anhydrates, polymorphs A and B, which were previously unidentified despite being part of the crystalline structure reported in the 1970s.

 

Dr. Alexander Sherwood, the lead author of the study and a medicinal chemist at Usona, emphasized that their approach involved piecing together available clues to construct a comprehensive understanding of the three psilocybin polymorphs. He stated, “The process of isolating and crystallizing pure psilocybin has been consistently replicated since its initial report in 1959, and various historical indicators pointed towards the existence of three psilocybin polymorphs resulting from this process.” Sherwood added, “The crystal structure solutions effectively amalgamated all historical evidence and data with precision and sophistication. By consolidating this information, a coherent and compelling narrative emerged regarding psilocybin crystallization.”

 

And Then An Unexpected Turn

 

The release of fresh information from a nonprofit dedicated to furthering our knowledge of psilocybin has provoked a dispute between corporations hoping to profit from new discoveries by obtaining patent protection and traditionalists who oppose psilocybin’s patenting.

 

Open Compass Pathways. COMP 360 is a synthetic psilocybin formulation made using crystalline psilocybin, created by this business. Compass Pathways received its fifth U.S. patent (U.S. Patent No. 11,180,517) from the U.S. invention and Trademark Office (USPTO) in November 2021. The invention covers crystalline psilocybin therapy approaches for treatment-resistant depression (TRD).

 

However, a petition filed on December 15 aims to challenge the patent granted on March 16, 2021. Further petitions challenging Compass’s patents are anticipated from Freedom to Operate (FTO), a non-profit organization dedicated to combating erroneous and unjustly issued patents in support of scientific advancement and education.

 

The December 15 FTO petition cited expert declarations from Dr. Sven Lidin (Dean at Lund University in Sweden) and Dr. James Kaduk (Professor of Chemistry at Illinois Tech and contributor to the Usona study). They assert that “Polymorph A” is merely a blend of known psilocybin polymorphs, rendering Compass’s patent invalid for claiming a non-existent polymorph.

 

This development raises questions about whether Compass can legitimately claim to have identified a new crystalline structure—a purported novel variant as mentioned in their patent application—for their synthetic psilocybin. Does the revelation by Usona and the contentions in the petition now nullify Compass Pathway’s patents on synthetic psilocybin?

 

Usona researchers also touched upon this matter in their study, recommending revisions to characterizations in recently granted patents that incorrectly depict crystalline psilocybin as a single-phase “isostructural variant.”

 

Simply put, the legitimacy of Compass’s patents utilizing crystalline psilocybin is up for debate—potentially rendering them invalid.

 

Yet, the clash between the Usona Institute and Compass Pathways underscores a broader issue between non-profit organizations in the psychedelics realm, such as Usona, focused on developing and enhancing therapeutic solutions for human ailments, and for-profit entities like Compass, aiming to establish control over the access and utilization of a natural substance.

 

This conflict raises pertinent questions for the psychedelics community: Who should have the authority to commercialize and regulate psilocybin? Or, perhaps more fundamentally, should such commercialization even be pursued?

 

The proliferation of patent applications has prompted the UC Berkeley Center for the Science of Psychedelics to launch a patent tracker. This initiative aims to monitor the progress of patent applications through the U.S. Patent and Trademark Office’s review process. The center highlights that a range of entities, including nonprofits, pharmaceutical firms, startups, and academic institutions, are vying to patent specific psychedelic compounds and formulations.

 

Carey Turnbull, the founder and director of FTO, articulates a nuanced perspective in a letter, stating, “No one disputes Compass’s role in manufacturing and distributing psilocybin for medical purposes, including myself. However, Compass’s efforts to monopolize psilocybin production and distribution raise concerns.” He adds, “(Compass) is seeking patents for inventions they did not create. While patents are an integral aspect of the system, the pursuit of patents that appropriate existing knowledge and then restrict its use represents a misuse of the system.”

 

Bottom Line

The clash over psilocybin patents epitomizes a broader ideological conflict within the psychedelics community, raising profound questions about ownership, commercialization, and ethical stewardship. As the debate intensifies and legal challenges unfold, it becomes increasingly clear that the future of psilocybin lies at the intersection of scientific innovation, corporate interests, and societal values. The outcome of this dispute will not only shape the landscape of psychedelic research and development but also have far-reaching implications for the accessibility and regulation of these substances. As stakeholders navigate these complex issues, it is imperative to prioritize transparency, collaboration, and the collective pursuit of knowledge for the betterment of humanity.

 

WHAT IS PSYCHEDELICS ALL ABOUT RIGHT NOW, READ ON…

BENZINGA PSYCHEDELICS

BENZINGA PSYCHEDELICS SHOW – IS THIS WEED 2.0?

 



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Your Dream Smoke Sesh Partner? Senator Warren Picked The Rock, Who Do You Got, Snoop? Musk? Rogen?

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Senator Warren Says Dwayne The Rock Johnson as Her Dream Smoke Sesh Partner, Who Are You Taking?

Senator Elizabeth Warren disclosed on Monday that her ultimate pick for a smoking buddy would be none other than Dwayne “The Rock” Johnson. The revelation came during a conversation with Jon Favreau, a former speechwriter for President Barack Obama and the host of “Pod Save America,” who presented Warren with a range of politician and celebrity options for her ideal smoking companions.

 

Warren’s enthusiasm was palpable when The Rock was proposed as a potential addition to her hypothetical “dream blunt rotation.” “Oh, The Rock! Oh, I’m stopping there,” Warren exclaimed. “I’m just choosing The Rock four times.”

 

In opting for the former wrestler turned Hollywood star, Warren passed over a slew of notable figures including President Biden, Vice President Kamala Harris, Senator Bernie Sanders, Treasury Secretary Janet Yellen, Senator Ed Markey, former House Speaker Nancy Pelosi, and Senator Chuck Schumer. She also declined the company of pop sensation Taylor Swift and rapper Snoop Dogg.

 

Despite the growing legalization of marijuana in several states, Warren was quick to clarify that her choices were not based on drug preferences. “These are people you’d go get pedicures with. This is what you’re telling me? I just want to make sure I’m following this,” she remarked to Favreau.

 

However, when pressed to assemble a “nightmare blunt rotation” from a list including Elon Musk, Senator Ted Cruz, Senator Mitch McConnell, Federal Reserve Chairman Jerome Powell, and Facebook founder Mark Zuckerberg, Warren demurred. “I’m starting to feel a little sick,” she joked. “That is really awful to contemplate.”

 

“Exploring Alternative Smoking Companions: A Diverse Selection to Consider”

 

The options for selecting a smoking partner are as endless as the types of cannabis available. People could be drawn to the easygoing charm of Seth Rogen among the plethora of alternatives, as his passion for cannabis is widely known, both on and off-screen. With his lighthearted humor and laid-back style, Rogen guarantees a fun and unforgettable smoking session full of smiles and positive energy.

 

For those seeking a spiritual and iconic experience, the legendary Bob Marley, if he were alive today, would undoubtedly be a top choice. Marley’s connection to cannabis was deeply rooted in his Rastafarian beliefs, and sharing a joint with him would be akin to communing with a cultural icon and musical legend. His presence would infuse the moment with a sense of reverence and cultural significance, making it an unforgettable experience for any cannabis enthusiast.

 

On the other hand, it’s impossible to overlook the appeal of smoking alongside cannabis culture pioneers like Snoop Dogg or Cheech and Chong. It would be like walking into a time capsule of cannabis history to share a smoke with these legends, who have long been associated with cannabis activism and the counterculture. An insightful and enjoyable smoking session full of tales and mutual admiration for the herb would surely result from their stories, humor, and enthusiasm for the plant.

 

In contrast to the countercultural cannabis heroes, the involvement of tech titans Elon Musk and Jeff Bezos brings a new depth to the discussion. Musk, known for his inventive projects and eccentric nature, is expected to add a thought-provoking and intellectually challenging component to the smoking experience. His ambitious ideas and forward-thinking attitude might spark exciting talks about the future of technology, space exploration, and more. Similarly, Jeff Bezos, with his entrepreneurial skills and huge fortune, might provide insights into business tactics and the nexus of commerce and cannabis. While their viewpoints may differ from the norm in cannabis culture, their presence would surely contribute to a varied and thought-provoking smoking session.

 

The Significance of Personal Connection in Choosing Smoking Companions

 

When selecting a smoking companion, whether real or hypothetical, the decision often extends beyond mere celebrity status or cultural significance. Instead, it reflects a deeper desire for personal connection and shared experiences that transcend the act of smoking itself.

 

Senator Elizabeth Warren’s decision to choose Dwayne “The Rock” Johnson as her perfect smoking partner is a powerful example of the value of a close relationship and mutual respect. Warren prioritizes true companionship and common interests over her fellow politicians and celebrities, as seen by her passionate endorsement of The Rock.

 

In the larger cannabis community, smoking sessions are seen as a chance for socializing and relationship development. This emphasis on interpersonal connection is prevalent. Smoking together creates a sense of oneness and understanding, whether it’s between strangers who bond over common hobbies or between old friends reminiscing over shared experiences.

 

Furthermore, Warren’s clarification that her choices were not based on drug preferences highlights the distinction between recreational activities and genuine companionship. In her view, the ideal smoking companion is someone with whom she can share laughter, meaningful conversation, and perhaps even a pedicure – activities that transcend the mere act of smoking and emphasize the importance of interpersonal connection.

 

In a world where technology and distance are playing a bigger role in facilitating social relationships, sharing a joint with a close friend provides a unique opportunity for real human connection. The importance of interpersonal connection when selecting smoking partners cannot be emphasized, whether it is by bonding over common experiences or having thought-provoking talks.

 

Bottom Line

 

Selecting a smoking companion embodies a deeper yearning for connection and shared moments. Senator Elizabeth Warren’s choice of Dwayne “The Rock” Johnson illustrates the value of genuine camaraderie over superficial fame. This sentiment resonates throughout the cannabis community, where smoking sessions serve as platforms for social bonding and mutual understanding. Whether with icons like Bob Marley, cultural pioneers like Snoop Dogg, or tech titans like Elon Musk, the act of sharing a joint fosters unity and meaningful interaction. Warren’s emphasis on personal connection, rather than drug preferences, underscores the distinction between recreational activities and genuine companionship. It highlights the multifaceted nature of relationships formed over a shared joint, where laughter, conversation, and even mundane activities are cherished. In a world increasingly driven by technology, the significance of interpersonal connection in choosing smoking partners remains paramount. It transforms the smoking experience into a profound celebration of human connection, enriching lives and forging lasting memories within the cannabis community.

 

WHO IS ON THE MT. RUSHMORE OF WEED, READ ON…

MOUNT RUSHMORE OF WEED

WHO IS ON YOUR MT. RUSHMORE OF WEED, DOES SETH ROGEN MAKE IT?



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The One Thing Every Cannabis Consumer Should Know? Reddit Users Give Insider Weed Tips for the Ages!

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What is something every cannabis consumer should know? Reddit Answers!

 

Individual expertise is often lauded as the pinnacle of knowledge, the concept of the “wisdom of crowds” emerges as a fascinating counterpoint, proving that collective intelligence can, in many instances, surpass the insight of any single person. This phenomenon, where group consensus leads to astonishingly accurate judgments, predictions, or solutions, hinges on the diversity of opinions, independence of contributors, and a means of aggregating these varied perspectives into a coherent whole. From predicting election outcomes to estimating the weight of an ox at a county fair, the wisdom of crowds has demonstrated its efficacy time and again, challenging the notion that experts alone hold the keys to knowledge.

 

Cannabis culture, with its rich tapestry of traditions, rituals, and shared experiences, serves as a prime example of this collective wisdom in action. Throughout history, cannabis users have passed down a repository of knowledge, from cultivation tips to consumption etiquette like the emblematic “puff, puff, pass” rule, ensuring that the communal pipe circulates in an orderly fashion. These unwritten rules and shared practices form a body of knowledge that is both practical and profound, embodying the spirit of community and mutual respect that defines cannabis culture.

 

Delving into the digital age, this tradition of shared wisdom has found a new home on platforms like Reddit, where communities of cannabis enthusiasts gather to exchange advice, experiences, and insights. One thread, in particular, stands out as a modern-day gathering around the proverbial campfire: a question posed to the masses, “What is something that you believe every cannabis user should know?” The responses to this inquiry offer a window into the collective psyche of the cannabis community, revealing a blend of humor, caution, and wisdom that can only emerge from a chorus of voices, each contributing their unique perspective to the conversation.

 

This article aims to explore the rich tapestry of advice, tips, and life lessons shared by Reddit’s cannabis community. By examining the most poignant, practical, and sometimes humorous responses, we’ll uncover the essential wisdom that every cannabis consumer, from the novice to the connoisseur, should know. Join us as we navigate through the smoke and mirrors, guided by the collective insight of countless individuals who have traversed the path of cannabis consumption before us.

 

 

The cannabis community is nothing if not generous with its collective knowledge. From age-old adages to modern consumption tips, the shared wisdom among cannabis enthusiasts is a testament to the plant’s communal spirit. A recent dive into a Reddit thread has unearthed some gems of advice that stand out not only for their practicality but for their reflection of the community’s core values. Here are some of the top-voted comments and why they’re crucial for every cannabis user to know:

 

You can use pipe cleaners to clean your pipes.

 

This piece of advice may seem straightforward, yet it’s a game-changer for anyone new to cannabis or those who have been improvising their cleaning methods. Pipe cleaners, originally designed for tobacco pipes, are perfectly sized and flexible enough to navigate the twists and turns of most cannabis pipes, ensuring a thorough clean. Keeping your pipe clean is not just about aesthetics; it’s about health, ensuring each hit is as pure and enjoyable as the first.

 

2When deciding how many edibles…You can always take more, but you can’t take less.

 

Edibles can be a delicious and effective way to consume cannabis, but their delayed onset can catch even experienced users off guard. This advice is a crucial reminder of the importance of dosing cautiously. By starting low and going slow, users can avoid uncomfortable experiences and find the dose that brings them the most pleasure and relief.

 

Stay hydrated.

 

Cottonmouth isn’t just an annoyance; it’s a sign that your body needs hydration. Cannabis can decrease saliva production, leading to dry mouth, which can be mitigated by keeping a bottle of water handy. Staying hydrated enhances the experience, ensuring you’re comfortable and focused on enjoying the high, not distracted by thirst.

 

If you have an underlying mental health disorder, cannabis can negatively amplify the symptoms.

 

Cannabis affects everyone differently, and for those with mental health conditions, it can sometimes exacerbate symptoms. This advice underscores the importance of self-awareness and possibly consulting with a healthcare provider to understand how cannabis interacts with mental health on an individual basis.

 

It affects your memory, as well as your memory.

 

This humorous comment highlights a well-known side effect of cannabis: short-term memory impairment. While usually temporary and often seen as part of the fun, it’s a gentle reminder to be mindful of your consumption, especially if you have responsibilities that require sharp recall.

 

Going for surgery? Tell the Anesthesia doctors that you smoke, and don’t lie about how much you smoke.

 

Cannabis can affect how the body responds to anesthesia, potentially requiring adjustments to dosages. Being honest with medical professionals ensures you receive the safest and most effective care, emphasizing the importance of transparency in all healthcare discussions involving cannabis.

 

It hits some folks very differently than others.

 

Cannabis’s effects can vary widely from person to person due to differences in body chemistry, tolerance, and the strain consumed. This diversity in experiences is a reminder of the subjective nature of cannabis use and the importance of finding what works best for you.

 

Cross joints are not worth the structural effort unless you are doing it for the swag points.

While a cross joint might look cool, thanks to popular culture, the effort to reward ratio is often skewed. This comment humorously points out that simpler methods of consumption are just as effective, if not more so.

 

Weed isn’t a personality.

 

Cannabis culture is rich and diverse, but it’s vital to remember that your worth isn’t tied to your consumption habits. This advice champions authenticity and finding a community that values you for who you are, not just for your shared interest in cannabis.

 

You smell like weed, you’re just smell blind to it

 

Cannabis has a strong, distinctive smell that can linger on clothes and in hair. This practical reminder is crucial for anyone who needs to maintain a certain discretion about their consumption, highlighting the importance of being mindful of your surroundings and the impression you leave.

 

Each of these pieces of advice from Reddit’s cannabis community embodies a blend of practicality, caution, and humor. Together, they form a guidebook for respectful, safe, and enjoyable cannabis consumption, reflecting the collective wisdom that makes the cannabis culture so unique and supportive.

 

 

The collective wisdom shared by the cannabis community on platforms like Reddit isn’t just anecdotal chatter; it’s a profound accumulation of experiences, trials, and errors that have been upvoted into the thousands, sometimes tens of thousands. These numbers are not mere metrics; they represent a communal nod of agreement, an acknowledgment that “Yes, this is the truth as we know it.” The practical tips, cautionary tales, and humorous observations that have resonated most profoundly within this community underscore a deep and nuanced understanding of cannabis and its effects on the body, mind, and social fabric.

 

These top comments, highlighted for their popularity and relevance, serve as guiding lights for anyone navigating the vast and sometimes overwhelming world of cannabis. They paint a picture of a community deeply aware of the plant’s powers and pitfalls. From the importance of starting low and going slow with edibles to the necessity of staying hydrated, these insights underscore the respect and mindfulness with which cannabis should be approached. Moreover, the discussions around mental health and the need for honesty with medical professionals about cannabis use reflect a mature, responsible stance towards consumption that prioritizes safety and health.

 

For newcomers to cannabis, the wisdom encapsulated in these Reddit threads is invaluable. It’s a distillation of countless personal journeys with the plant, offering a roadmap through potential challenges and towards more enriching experiences. If you’re new to cannabis, taking a long, hard think about what’s been written here isn’t just advisable; it’s essential. These insights offer a foundation upon which to build your own relationship with cannabis, informed by the collective experiences of a community that spans the globe.

 

The sticky bottom line is this: the cannabis community’s shared wisdom, as demonstrated in these top comments, reveals a sophisticated, multifaceted relationship with the plant. It’s a relationship characterized by enjoyment, caution, and an ongoing commitment to learning and sharing knowledge. For anyone embarking on their cannabis journey, there’s perhaps no better starting point than the lived experiences of those who have walked the path before. In this community’s wisdom, there’s a wealth of knowledge waiting to be tapped into, ensuring that your journey with cannabis is as safe, enjoyable, and enriching as possible.

 

REDDIT ON CANNABIS, READ ON…

REDDIT CANNABIS TIPS

THE REDDIT GUIDE TO HEALTHY CANNABIS HABITS, READ THIS!

 



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