Connect with us

Cannabis News

Cannabis and Antibiotics – What is the Deal, Can You Smoke Pot While Using Antibiotics?



Experts weigh in on the question of whether it’s okay to indulge in cannabis while on antibiotics. As we all know, alcohol consumption is a no-no while on medication. But what about cannabis use on medication?


It is crucial to be mindful of drug interactions! There’s the need to be vigilant of your consumption when taking medication. Combining certain substances can result in adverse reactions or heightened effects.


Fighting bacterial infections requires antibiotics, but with these prescriptions come strict guidelines. A crucial yet often overlooked question remains: is it safe to spark up while on antibiotics?


Canada’s Medicinal Cannabis Resource Centre Inc., Terry Roycroft, is the Canadian expert on the matter and canaanswer the burning question. With over a decade of research and study on marijuana, Roycroft and the MCRCI team work closely with doctors who specialize in the medical use of cannabis.


Fortunately, according to the expert, smoking marijuana while on antibiotics may not be as harmful as previously believed.


Can you smoke weed on antibiotics?

Antibiotics are a go-to for combating bacterial diseases, either by eliminating the bacteria or hindering its expansion. Unfortunately, some bacteria have developed antibiotic immunity, making treatment more challenging.


As for using cannabis while on antibiotics, it’s not a straightforward answer. Due to the federal ban on marijuana, thorough studies examining the interaction between antibiotics and cannabis are limited, making it difficult to determine their effects together.



How Dangerous are Interactions?

As Roycroft explains, everyday substances can interact with medication, citing caffeine as an example, with 82 recorded interactions, some of which are moderate to severe.


The UK’s National Health Service advises caution when consuming alcohol while on antibiotics, with only two medications – metronidazole and tinidazole – requiring complete abstinence. Even seemingly harmless fruits like grapefruit can negatively interact with antibiotics.


Grapefruit’s impact on drug metabolism, including antibiotics used to treat infections, led experts to use it as a benchmark for studying the interactions of cannabis. Roycroft notes that this fruit can interfere with the effectiveness of several medications.


Contrary to popular belief, cannabis has very few interactions with antibiotics, says Roycroft, noting that antibiotics aren’t even listed as contraindicators with the plant. The few interactions that have been identified are mild, and doctors are even exploring the possibility of enhancing the efficacy of antibiotics with the addition of marijuana.


Roycroft shares how combining cannabis and antibiotics can lead to positive results. When treating patients on pain medication, the introduction of cannabis often halves the dose of antibiotics while achieving the same benefits and reactions as with a total quantity.


While interactions between antibiotics and marijuana are mild, they can still be felt by those who choose to mix the two. Jessie Gill, a medical nurse specializing in medical marijuana, warns that some macrolide antibiotics like troleandomycin may interact with cannabis.


Gill warns that marijuana’s inhibition of cytochrome p450, a liver enzyme utilized by several medications, including antibiotics, can amplify the effects of the medication and raise the risk of experiencing side effects and adverse reactions. In her words on Quora, ‘Marijuana inhibits a specific enzyme in the liver, cytochrome p450. This enzyme is used by many medications, including some antibiotics, meaning the effect of the medication will be increased, and the risk of experiencing side effects and adverse reactions will be higher.


What about consuming CBD?

Surprisingly, studies reveal that CBD may possess antibiotic properties. According to Newsweek, Australian scientists discovered that cannabidiol effectively killed several strains of bacteria, including those resistant to traditional antibiotics. Although the findings are intriguing, there’s still a long road ahead before CBD can fully replace antibiotics.


The senior research chemist at the Centre for Superbug Solutions, Mark Blaskovich, remains cautious about the findings. Telling Newsweek, ‘We still don’t understand how it works, and it may have a distinct mode of action against bacteria resistant to other antibiotics, but we just don’t know yet.


Blaskovich adds that so far, research has only demonstrated its effectiveness on skin surfaces. Still, for it to be precious, we need to prove it can treat systemic infections such as pneumonia or complicated tissue infections that require oral or IV dosing. Unfortunately, early studies have yet to show promising results in these more challenging scenarios.



So, Should You Use Cannabis While on Antibiotics?

According to Roycroft, there is little to worry about when it comes to mixing cannabis with antibiotics. Although, some individuals may feel heightened side effects from the medication. The Medicinal Cannabis Resource Centre Inc. has patients who use both, and they do not advise stopping their cannabis consumption.


It’s up to the individual to determine if they want to mix cannabis with antibiotics, and consulting a medical professional is always a safe bet. However, using grapefruit as a benchmark can help determine if there could be any potential conflicts with medications. If there’s a warning against consuming grapefruit with your antibiotics, it may be best to avoid combining the two with cannabis. Of course, getting an expert opinion from your doctor is always a wise choice.



It is evident that the relationship between cannabis and antibiotics is not as severe as one might expect. Although some mild interactions have been reported, it is generally considered safe to use both substances together. However, as with any medication, it is always best to consult a healthcare professional to ensure you receive the best possible advice tailored to your needs.


Ultimately, the Medicinal Cannabis Resource Centre Inc. would not tell their patients to stop using cannabis while taking antibiotics. If you are still concerned about mixing the two, you should speak with a healthcare professional. They may use grapefruit as a guide, as there are contraindications between grapefruit and certain medications.


In the end, whether it is cannabis and antibiotics or any other combination of substances, it is always best to avoid caution and consult with a medical professional. They can help guide you in making the best decisions for your health and well-being.





Source link

Cannabis News

What is Cannabis Poisoning? – CNN Makes Up a New Reefer Madness Term




cannabis poisoning

What is Cannabis Poisoning? – CNN Makes Up a New Reefer Madness Term No One Ever Heard of Before!


What is a poison? According to

a substance that is capable of causing the illness or death of a living organism when introduced or absorbed.

“he killed himself with poison”.


The Mayo Clinic defines poisoning as:

Poisoning is injury or death due to swallowing, inhaling, touching or injecting various drugs, chemicals, venoms or gases. Many substances — such as drugs and carbon monoxide — are poisonous only in higher concentrations or dosages. And others — such as cleaners — are dangerous only if ingested. Children are particularly sensitive to even small amounts of certain drugs and chemicals.


CNN recently upped their anti-pot rhetoric by claiming a new term, “cannabis poisoning”, have tripled in older adults, in this case, in Canada.


Since no one has ever died from cannabis, as in an overdose or ingesting too much, CNN must be referring to the “injury” part of the poisoning definition that the Mayo Clinic describes.


What injuries has cannabis caused in the human body to be classified as poisoning.  Greening Out, a common term for ingesting too much THC that leads to paranoia, possible hallucinating, and a great night sleep, is as far a stretch from “poisoning” as the cannabis industry gets. Yes, people using cannabis can do acts under the aspis of being “high”, walking into walls, falling down stairs, etc. that can cause injury, but that would be injuries under the influence, not poisoning injuries.


CHS, or cannabinoid hyperemesis syndrome, is a longer-term reaction that a small percentage of habitual cannabis users can develop when their bodies have large amounts of THC in their liver and kidneys to flush. Usually taking a 10-day break, or up to a month, can solve most CHS issues.


These would be considered a toxicity problem, not a poison problem.


CNN, notoriously famous for anti-cannabis, clickbait headlines and brash statements about the “dangers” of cannabis, hit a new low with creating a new term, “cannabis poisoning”. It is a misleading term medically to say the least, let alone the implication that a serious poisoning of weed could lead to death or serious injury.  Neither of which has ever happened in 5,000 years of humans using the cannabis plant.





Source link

Continue Reading

Cannabis News

The 3 Biggest Winners from Rescheduling Cannabis?




tax money weed

President Joe Biden’s support of the administration’s decision to reschedule cannabis from Schedule I to Schedule III is likely to result in considerable financial benefits for large, legal cannabis businesses and the illicit market. This action may lessen the restrictions imposed by IRS tax regulation 280E, which has banned cannabis businesses from deducting standard business expenditures. Which cannabis firms will gain the most from this change?


The illicit market will get a huge boost by removing the punshiments associated with getting caught dealing or transporting a Schedule 1 drug.  Now that the fines, prison sentences, and desire to enforce Schedule 3 crimes is lessened, look for the illicit market to boom across America.  It is estimated that the illegal cannabis market is 3x the size of the legal US market as of 2024, so look for that multiple to expand if Schedule 3 is enacted.  Removing a negative incentive in economics always leads to predictable action.


In the legal market, the largest MSOS, or those that paid the most taxes, have the most to gain by a repeal of the 280E tax code and future tax credit or refunds coming their way


Industry Leaders in Tax Payments


Rescheduling cannabis will abolish the onerous 280E tax law, potentially freeing up more than a billion dollars in tax savings for the business. Curaleaf (OTC: CURLF) and Trulieve (OTC: TCNNF), both of which make considerable tax payments, are among the firms most likely to profit. Repealing 280E limits would allow these businesses to deduct typical business costs, greatly improving their financial situation.

Truelive alone stands to get $113,000,000 in tax refunds and savings!

Senior analyst Pablo Zuanic of Zuanic & Associates believes that these tax reductions may result in improved cash flows, allowing these businesses to reinvest in development and growth. In the quickly changing cannabis market, having this kind of financial flexibility is essential for keeping a competitive advantage and encouraging creativity.


Zuanic has consistently highlighted the disparity between current market valuations and the potential upside, particularly if federal legalization occurs. He emphasizes that immediate cash flow improvements could lead to substantial revaluation of these companies. By enabling the deduction of ordinary business expenses, the financial statements of these companies would more accurately reflect their true profitability, attracting more investors and boosting market confidence.


The potential tax savings are a temporary relief and a game-changer for the industry. Analysts believe that the improved cash flow could result in substantial revaluations of cannabis companies. For Curaleaf and Trulieve, this change would mean their financial statements would better represent their actual profitability, leading to increased investments and further expansion opportunities.


Curaleaf’s Financial Outlook


Beacon Securities’ Russell Stanley sheds light on Curaleaf’s financial landscape, highlighting the company’s adept management of operating cash flow. This proficiency facilitated a successful debt repurchase post-quarter, significantly enhancing its financial stability. With the anticipated rescheduling of cannabis and the potential enactment of the SAFER Banking Act, Curaleaf stands to benefit from a transformed financial environment, potentially witnessing a substantial surge in its operating cash flow by up to 92% and free cash flow by 188%.


Wedbush Securities recently released a report on Curaleaf, elevating the stock’s 12-month price target from $6.00 to $7.00 while maintaining a buy recommendation. The report underscores Curaleaf’s commendable performance in key domestic markets like Connecticut, Arizona, Maryland, and New York. Projections indicate a revenue uptick to $1.50 billion by 2025, coupled with improvements in overall profitability. This optimistic forecast reflects the company’s robust financial position and its strategic market presence.


Proactive debt management techniques and well-thought-out market positioning highlight Curaleaf’s potential for long-term development and financial success in the changing cannabis industry. Curaleaf is in a strong position to benefit from the rescheduling of banking and cannabis legislation, which may lower regulatory obstacles and further establish the company’s leadership in the cannabis market.


Unlocking Trulieve’s Growth Potential


Trulieve’s Growth Trajectory


Trulieve’s growth trajectory is drawing attention, particularly from Needham’s Matt McGinley, who emphasizes the company’s operational efficiency. McGinley points out that Trulieve has achieved its highest gross margin and EBITDA rates observed in over two years, indicating strong operational performance. This efficiency positions Trulieve favorably for capitalizing on emerging opportunities in the cannabis market.


Key legislative advancements in pivotal markets such as Florida and Pennsylvania present significant growth potential for Trulieve. As these markets potentially transition to adult-use cannabis, Trulieve stands to benefit from increased demand and expanded market reach. Leveraging its operational efficiency and established market presence, Trulieve is poised to capitalize on these legislative shifts to drive revenue growth and enhance shareholder value.


Trulieve is positioned to be a major participant in the growth of the cannabis sector due to its strategic focus on operational excellence and its flexibility in responding to changing regulatory environments. Trulieve is in an excellent position to maintain its growth trajectory and establish itself as a top cannabis supplier, thanks to encouraging legislative changes and a proven track record of high performance.


Analysts’ Industry Impact Assessment


Viridian Capital Advisors offers insights into the industry impact, noting that ten MSOs exceeded EBITDA estimates by $37 million in the first quarter of 2024. This performance suggests that initial projections may have been conservative, indicating a positive trend for cannabis companies. Analysts from Viridian specifically highlight Curaleaf and Trulieve, among others, as poised to benefit from the financial changes resulting from the removal of 280E tax restrictions.


The long-term outlook for the cannabis industry remains bullish, with potential federal legalization driving substantial valuation growth. Pablo Zuanic from Zuanic & Associates suggests that the US market alone could justify over $110 billion in valuations by 2030 assuming federal legalization. The removal of tax restrictions would directly impact bottom lines, potentially leading to significant valuation increases for many cannabis stocks.


All things considered, the possible repeal of the 280E tax laws offers cannabis businesses a big chance to improve their financial standing and market value. As analysts speculate that early projections may have overestimated the sector’s potential, businesses like Curaleaf and Trulieve might gain from more cash flow and better profitability, setting them up for long-term success in the changing cannabis market environment.


Bottom Line


The impending rescheduling of cannabis and the potential repeal of IRS tax regulation 280E offer a substantial opportunity for cannabis companies to strengthen their financial positions and market appeal. Industry leaders such as Curaleaf and Trulieve stand to benefit significantly, with projected increases in cash flow and profitability paving the way for sustained growth. Analysts anticipate a positive market response, with potential valuation growth and a bullish outlook for the long-term trajectory of the cannabis industry. These regulatory changes mark a pivotal moment, allowing businesses to capitalize on newfound financial flexibility and attract investor confidence. As the sector continues to evolve, Curaleaf, Trulieve, and other key players are positioned to thrive, driving innovation and shaping the future of the cannabis market.





Source link

Continue Reading

Cannabis News

How Potent is Illegal Weed




potency of street weed

The average THC potency of illegal weed is only 16%, same as legal cannabis says DEA?

In the ever-changing landscape of cannabis, a striking revelation has come from the U.S. Drug Enforcement Administration (DEA). A recent statement established that the average potency of illicit marijuana flower stands at a industry standard of 16%. Understanding the implications of such a percentage requires a deeper dive into the realm of cannabinoids, particularly THC (tetrahydrocannabinol).


 The Evolution of THC Potency

THC is the main psychoactive compound in marijuana, responsible for the “high” that users experience. The potency of marijuana, measured by its THC content, has dramatically increased over the past few decades. To understand the context:


  • 1980s:The average THC content of seized marijuana was below 4%.

  • 1990s: This figure began to climb, reaching around 5-6%.

  • 2000s: Potency continued to increase, hitting approximately 10-12%.

  • 2020s: Current reports indicate an average of 16%, with some samples even exceeding 30%.


This increase is primarily due to advanced cultivation techniques, genetic selection, and the growing demand for stronger marijuana.


Factors Contributing to Increased THC Potency

Several factors have contributed to the rising THC levels in illicit marijuana:


  • Selective Breeding: Growers have increasingly focused on breeding strains with higher THC content to meet market demand.

  • Advanced Cultivation Techniques: Techniques such as hydroponics, controlled environments, and optimized nutrient delivery have enabled the production of more potent marijuana.

  • Genetic Modification: Some strains have been genetically modified to enhance THC production.


Public Health Implications


The rise in THC potency has several significant public health implications:

  • Increased Risk of Negative Effects

  • Heightened Anxiety and Paranoia: Elevated THC levels can induce intense anxiety and paranoia, especially in inexperienced users or individuals with existing mental health issues.

  • Acute Psychosis: The likelihood of encountering psychotic episodes rises significantly with higher doses of THC.

  • Cognitive Decline: Prolonged use of marijuana with high THC content can result in enduring cognitive impairments, particularly impacting memory and learning abilities.



  • Adolescents: Young users are more susceptible to the negative effects of high-THC marijuana, including impacts on brain development.

  • Individuals with Mental Health Issues: Those with pre-existing mental health conditions may experience exacerbated symptoms.


  Regulatory and Law Enforcement Challenges

The DEA’s report underscores significant obstacles faced by law enforcement and regulatory agencies:

  • Persistent Black Market: Despite legalization in several states, the black market for marijuana persists, often offering more potent products than those available in legal dispensaries.

  • Ensuring Consumer Safety: The unregulated nature of black market products results in unpredictable potency and potential contamination with harmful substances.


To address these issues, regulatory bodies need to:


  • Implement Stricter Controls: Introduce more stringent regulations for marijuana potency in both legal and illegal markets.

  • Increase Monitoring and Enforcement: Enhance efforts to monitor and dismantle illegal growing operations.

  • Educating Consumers: Consumer education is crucial in mitigating the risks associated with high-THC marijuana

  • Public Awareness Campaigns: Launch campaigns to inform the public about the potential dangers of high-THC marijuana.

  • Educational Programs: Develop programs targeted at specific groups, such as adolescents, to educate them about the risks.


Key points to emphasize in these programs include:


  • Understanding THC Levels: Educate consumers on how to read and understand THC levels on product labels.

  • Recognizing Symptoms of Overconsumption: Teach users how to recognize signs of overconsumption and what to do if they experience adverse effects.

  • Safe Consumption Practices: Promote safe consumption practices, including starting with low doses and waiting to see the effects before consuming more.

 Future Trends and Research

Ongoing research and monitoring are essential to adapt to the evolving marijuana market:

  • Long-term Health Effects: Conduct studies to understand the long-term health effects of high-THC marijuana use.

  • Impact on Mental Health: Investigate the relationship between high-THC marijuana use and mental health conditions.

  • Comparative Studies: Compare the effects of high-THC marijuana with other forms, such as CBD-dominant strains, to provide a comprehensive understanding of marijuana’s impact.

Potential Solutions and Innovations

To address the challenges posed by high-THC marijuana, several solutions and innovations can be explored:

  • Development of Low-THC Strains: Encourage the development and use of low-THC, high-CBD strains that provide therapeutic benefits without strong psychoactive effects.

  • Improved Testing Methods: Invest in better testing methods to accurately measure THC content and detect contaminants.

  • Policy Reform: Advocate for policy reforms that support research and responsible use, including:

  • Incentives for Low-THC Products: Provide incentives for the production and sale of low-THC products.

  • Support for Medical Marijuana Research: Increase funding and support for research into the medical uses of marijuana.

Industrial and Economic Implications

The rise in THC potency also has significant industrial and economic implications:


The marijuana industry has become a significant economic driver in states where it is legal, contributing to tax revenues and job creation.

However, the black market remains a substantial challenge:

  • Revenue Losses: Illegal sales undermine tax revenues that could be used for public health and safety programs.

  • Market Competition: Legal businesses face unfair competition from black market operators who do not adhere to regulatory standards.

Engaging Stakeholders and Community

A critical aspect of addressing the challenges associated with high-THC marijuana is engaging with and gaining the support of local communities, policymakers, and industry leaders. The Ohio company has launched outreach programs to educate stakeholders about the benefits of bioplastics and the specific advantages of using hemp as a raw material.

Community involvement is crucial, especially in providing local farmers with the tools and knowledge needed to transition to hemp cultivation. Through:


  • Training Sessions

  • Pilot Programs

The company aims to build a robust local supply chain that can sustainably support large-scale bioplastic production.


In conclusion, the DEA’s report on the average THC potency of illicit marijuana flower reaching 16% highlights the significant changes in the marijuana landscape over recent decades. This increase poses new challenges for public health, regulation, and consumer safety. Addressing these challenges requires a multi-faceted approach involving education, regulatory reforms, technological advancements, and community engagement. By fostering a comprehensive understanding of the risks and benefits associated with high-THC marijuana, stakeholders can work together to ensure that the benefits of marijuana legalization are maximized while minimizing potential harms. This approach promises a healthier, safer future for all users and communities involved.





Source link

Continue Reading


Copyright © 2021 The Art of MaryJane Media