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CBG Vs. CBN: Which One Is Best For Sleep, Anxiety, And Pain Management?

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In recent years, CBD has become popular for those seeking natural solutions for various health concerns, such as stress and anxiety reduction, pain management, and improved sleep. CBD is just one of the many cannabinoids found in the cannabis plant, along with THC and other lesser-known cannabinoids like CBG and CBN.

CBG and CBN are non-psychoactive cannabinoids that are believed to offer a range of health benefits. Although not as widely recognized as CBD or THC, these cannabinoids are slowly gaining attention for their potential daily and long-term health benefits.

This guide delves into the differences between CBG and CBN, their potential effects, and their legal status. By the end, you will have a clearer understanding of these two cannabinoids, allowing you to decide which is right.

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What Is CBG?

CBG, a minor cannabinoid found in the hemp plant, boasts a range of potential health benefits, including reducing inflammation, providing pain relief, and aiding in chronic illnesses. Despite being present in trace amounts, it is referred to as the “mother cannabinoid” as it is the starting point for other cannabinoids like CBD and THC.

What Is CBN?

On the other hand, CBN is a unique cannabinoid that is formed through the exposure of THC to heat, light, or pressure. Unlike CBD and CBG, it is not naturally present in the plant but is a byproduct of the activation process.

RELATED: Is CBN The Fountain Of Youth? Here’s What A Recent Study Found

While CBG has an energizing effect, boosts mood, and is stimulating, CBN is primarily used as a natural sleep aid and has shown promise in easing anxiety.

Extraction Process of CBG and CBN

CBG and CBN are not commonly found in large quantities in the cannabis plant, so specialized extraction methods are needed to isolate these valuable cannabinoids.

Cannovia only uses supercritical CO2 extraction, considered the best method for extracting CBD, CBG, and other cannabinoids. This method uses carbon dioxide as a solvent, making it safer and more efficient to extract cannabinoids without any toxic chemicals or residues left behind.

RELATED: CBG Mania: What Are the Best Ways To Use And Consume CBG?

In comparison, other extraction methods, such as ethanol and steam distillation, can leave behind harmful impurities and contaminants, affecting the quality of the product. CO2 extraction, on the other hand, can extract a broader range of cannabinoids and terpenes, making the final product more potent and providing a more comprehensive range of health benefits.

For the highest quality CBD, CBG, CBN, or other cannabinoid products, look for those extracted using a CO2 extraction. This method guarantees a safe, pure, and potent product that benefits you and your loved ones.

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Possible Medical Application of CBG and CBN

CBG and CBN are on the radar for their potential medical benefits. CBG may help treat neurological disorders, relieve pain, regulate hormones, combat bacteria, treat skin conditions, and more. There is also early evidence of CBG’s anticonvulsant properties and potential to reduce seizures.

On the other hand, CBN is being explored for its pain-relieving effects, anti-inflammatory properties, and ability to protect the nervous system, increase appetite, and assist with sleep. Despite anecdotal evidence of CBN’s popularity as a sleep aid, more research is necessary to understand its potential fully.

Dosage Requirement

Finding the perfect dose for CBN and CBG can be a journey of discovery. It’s always best to start with the product’s recommended dose and adjust accordingly to achieve the desired outcome.

Remember, starting low and gradually increasing your dose is essential to find what works best for your needs. Factors such as your body weight, metabolism, and desired result can impact your optimal amount. Take your time, listen to your body, and find the right balance.

Do CBG and CBN Have Any Psychoactive Effects?

Unlike THC, the primary psychoactive cannabinoid found in the cannabis plant, CBD, CBG, and CBN are considered non-psychoactive and do not alter the mental state or produce a high. However, individual reactions to these cannabinoids may vary, so it’s essential to be aware of any changes you may experience when using cannabis products.

Availability of CBN and CBG Products

Finding CBG and CBN on their own can be challenging, as they are found in smaller amounts in the cannabis plant. Fortunately, these non-psychoactive cannabinoids can often be discovered in full-spectrum CBD products, such as oils, tinctures, and topicals.

When looking for high-quality CBD products, it’s crucial to remember that they contain small amounts of CBG and CBN alongside CBD and other cannabinoids.

RELATED: CBD, CBDa & CBGa: What’s The Difference?

However, the availability of CBG and CBN products may not be as readily accessible as CBD products and can sometimes come at a premium price. It’s essential to research and invest in a trustworthy CBD brand that offers pure, high-quality CBD products to ensure you get the most out of your wellness journey.

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Legality of CBG and CBN in the US

CBG and CBN are not categorized as controlled substances in the United States, making them legal for sale and possession in most locations. This differs from THC, a Schedule I drug that is against federal law.

RELATED: Is CBN A Controlled Substance? Yes. No. Maybe.

It’s crucial to remember that the legality of cannabinoids can vary by state, so it’s always wise to check the regulations in your area before using or purchasing CBG or CBN products.

Will CBN and CBG Show Up on a Drug Screening?

It’s important to know that drug tests look for specific substances in your body. However, the good news for those who take CBG or CBN – these cannabinoids are not usually tested for in drug tests. This is because they are not considered controlled substances and are not known to cause psychoactive effects. So, you can feel confident that taking CBG or CBN won’t impact your drug test results.

CBG Vs. CBN: Which Is Better?

Determining which cannabinoid is best is a highly personal decision, as the effectiveness of each varies from person to person. CBG may be an excellent choice for boosting energy levels, improving gut health, and reducing inflammation. On the other hand, those seeking relief from anxiety and pain, as well as better sleep, may find CBN to be the most beneficial. Ultimately, the right choice will depend on individual goals and needs.

Conclusion

CBG and CBN are promising non-psychoactive cannabinoids starting to gain recognition for their potential health benefits. Whether you’re seeking relief from pain, anxiety, or sleep issues, these cannabinoids may have something to offer. However, as with any supplement, it’s essential to research, choose high-quality products, and talk to your doctor before using CBG or CBN. With the right approach, these natural compounds may help you achieve your health and wellness goals and be a step toward a happier, healthier you.

This article originally appeared on Cannabis.net and has been reposted with permission.



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LSD Effective in Treating Anxiety, Phase II Clinical Trial Shows

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A new drug known as MM-120, which is a more pharmacologically optimized form of popular psychedelic lysergic acid diethylamide (LSD), just entered phase II clinical trials for the treatment of generalized anxiety disorder (GAD) and other mental health disorders.  

What is LSD? 

LSD is a potent hallucinogenic which belongs to a class of drugs called ergolines (more specifically, LSD is an ergoline-based tryptamine compound), meaning it’s derived from the ergot fungus. Despite this, it still requires a lot of human processing to become LSD, so it’s not considered a natural entheogen like psilocybin or mescaline. LSD was first synthesized by Swiss chemist Albert Hoffman in 1938, but it wasn’t until 1943 that its effects were fully realized when Hoffman accidentally ingested a small amount from his lab.  

As a psychedelic, standard effects include various sensory hallucinations (visual, auditory, sensory, olfactory, etc.), as well as altered perception, feelings, and thoughts. Something that makes LSD unique is the duration and intensity of the hallucinogenic trip, which often ranges from 6 to 12 hours but has been reported to last even longer. This could be due to the way the drug binds to receptors in the brain. 

Like other tryptamines, LSD interacts with serotonin receptors, in particular, receptor 5-HT2AR. Something interesting that happens when LSD binds to 5-HT2AR, is that the receptor closes over the molecule, preventing it from leaving the brain quickly. This could explain why the effects of LSD seem to last after it has left the bloodstream.  

From this point, the serotonin receptor will activate two signaling pathways between the cells, via G-proteins and β-arrestins. LSD function primary through the latter, but that’s not always the case. Overall, ergoline compounds can be a bit mysterious in their processes, because different subgroups can have different effects on serotonin receptors. Add to that, newer research found that ergoline compounds can actually modify the structure of the receptors they interact with, in order to activate different effects.  

MM-120 clinical trials  

MM-120 (lysergide d-tartrate) is a new drug developed by MindMed, a biotech company the focuses on psychedelic-based medications. This drug is a “new and improved” version of LSD that is currently undergoing clinical trials for the treatment of generalized anxiety disorder (GAD). The most recent results from phase II of testing found that the drug candidate, particularly at the 100 µg dose, “demonstrated effectiveness, significantly reducing anxiety symptoms.” 

MindMed logo (source: www.mindmed.co)

Dr. Daniel Karlin, chief medical officer of MindMed, explained the key findings in an interview with Medical News Today: “MindMed conducted this study with participation from 198 patients, all of whom suffered with a primary psychiatric diagnosis of generalized anxiety disorder (GAD), across 20 clinical sites in the United States.” 

“Participants were divided into 5 study arms; each arm received a single dose of a lysergide-based drug candidate, called MM-120 (lysergide d-tartrate), or a placebo,” Dr. Karlin continued. “Among the four groups that received a dose of MM-120, doses were 25, 50, 100, or 200 µg of MM-120. Importantly, no form of additional therapy was given to any participant. The study design evaluated the stand-alone effects of the drug candidate, MM-120,” he added. 

Karlin continued: “The data available to us at this time show that patients experienced meaningful and lasting symptom reduction. Four weeks following a single dose of MM-120, 78% of participants who received either a 100 or 200 µg dose measured as having a clinically significant response to the drug. 50% of participants who received the 100 µg dose were considered to be in clinical remission at Week 4, meaning that the patient no longer suffered from clinically significant symptoms of GAD.”  

Psychedelics for mental health disorders  

Over the years, psychedelics have proven themselves to be one of the most successful treatment options for many different mental health disorders. An overwhelming 82% percent of Americans are in favor of accelerating research on this front, but federal regulations have really been a stick in the wheel of progress here. Given the introspective and sentient nature of psychedelics, it makes sense that using them therapeutically can help a person be more honest, open, and transparent.  

Although discussion of using psychedelics therapeutically is pretty fresh for most of us, many cultures have been utilizing entheogens medicinally and in religious rituals for thousands of years. Even scientists in United States and Europe were conducting research on psychedelic compounds for the treatment of mental illnesses, and it all really began to gain traction throughout the 1940s and 1950s. 

In 1943, Swiss-chemist Albert Hofmann first synthesized lysergic acid diethylamide and by the early 1950s, psychiatrist Humphry Osmond had already pioneered a treatment regimen using LSD to cure alcoholism and other mental disorders; with relative success might I add. Osmond is the one who coined the term ‘psychedelic’, meaning ‘mind manifesting’. He also oversaw author Aldous Huxley’s infamous, therapeutic mescaline trip in 1953.  

Psychedelics have been proven effective in treating various mental health disorders

Numerous psychedelic studies were in the works during that time, but all that research was derailed for social and political reasons when entheogenic compounds were banned at the start of the 1970s. Fast forward a few decades, and we are now beginning to see a growing acceptance of these compounds, especially the naturally-derived ones, and thus, an uptick in research. One of the main areas of interest is how psychedelics can help with mental health disorders such as depression, PTSD, and addiction.  

“The evidence suggests mystical experiences help people gain a new perspective on their issues,” said Matthew Johnson, the Susan Hill Ward professor in psychedelics and consciousness at the Johns Hopkins School of Medicine. “We think the long-term biological changes will be similar to those with successful psychotherapy. Essentially, the person has learned something about this problematic behavior in their life and changed their life as a result.” 

Final thoughts 

MM-120 is the closest we’ve ever had to a clinically-proven and FDA-approved LSD-based medication. Phase II trials are currently underway, so it’s well on the path to becoming available via prescriptions in select markets, although it could still be some time before we can expect more widespread use of this drug.

Hello readers. We’re happy to have you with us at Cannadelics.com; a news source here to bring you the best in independent reporting for the growing cannabis and hallucinogen fields. Join us frequently to stay on top of everything, and subscribe to our Cannadelics Weekly Newsletter, for updates straight to your email. Check out some awesome promos for cannabis buds, smoking devices and equipment like vapes, edibles, cannabinoid compounds, amanita mushroom products, and a whole bunch more. Let’s all get stoned together!



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Cannabis and Fitness: Enhancing Your Workout Experience

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In the realm of muscle building, cannabis can complement traditional approaches by addressing key aspects of the process. Cannabis’s pain-relieving properties can alleviate post-exercise soreness, facilitating faster recovery and subsequent workouts. Moreover, cannabis may reduce stress levels, promote better sleep, stimulate appetite, and enhance focus, all of which are conducive to muscle growth and development.



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A Comprehensive Guide to Improving Your Pet’s Wellness

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CBD for Pets: A Comprehensive Guide to Improving Your Pet’s Wellness























Learn about the potential benefits of CBD for pets, the science behind it, and discover how to safely incorporate this natural compound into your pet’s routine for better health and well-being.



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