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Does A Medical Setting Affect Psychedelic Treatment?

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As psychedelics gain acceptance quickly, laws in different states are changing to accommodate their possession and use. So far though, the only states to legalize have done so with an allowance for use in a medical/supervised setting. How useful is this medical setting to psychedelic treatment, and can it get in the way?

What is a medical setting?

When it comes to using psychedelics, there are no specific rules for what will lead to a good trip, and what will bring on a bad one. Though this can do with individual reaction to the drug, it also has to do with outside factors that can impact our individual reaction. We’re often told ‘set and setting’ play a big role in a trip going smoothly, and this can encompass different factors.

‘Set and setting’ refers to the place you’re having the experience, and the environment around. You could be in the woods, or on the beach, or at a dance club, or alone with your partner. The environment around might include the other people you’re interacting with, how crowded it is, if other people are also having the same experience, if you’re doing something organized or on your own, lighting and sound, and even the weather around you.

A medical setting is another type of setting, but until recently, it wasn’t associated with taking a psychedelic drug, or hallucinogen of any kind. However, as research amps up, and legalizations roll in, that idea of a medical, or supervised setting, becomes that much more important, as it’s the only setting legally available to use the compounds in question.


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A medical setting is not one specific thing. Also referred to as a ‘healthcare setting,’ and expanding into ‘supervised setting’, this term encompasses: “acute care hospitals, urgent care centers, rehabilitation centers, nursing homes and other long-term care facilities, specialized outpatient services (e.g., hemodialysis, dentistry, podiatry, chemotherapy, endoscopy, and pain management clinics), and outpatient surgery centers. In addition, some healthcare services are provided in private offices or homes.”

The last one is important, because it reminds us that our own home can be a medical setting under the right conditions; which is the medical setting most people should automatically be the most comfortable with. And when it comes to ketamine, it is offered by many clinics as an at-home treatment which both cuts costs, as well as gets away from the medical setting that not everyone is comfortable with.

In reality, both current psychedelics legalizations aren’t for medical use, and the legislation uses the term ‘service center’ instead. Considering it’s a formal setting, with a person watching over, it represents essentially the same thing. Perhaps its not so much about a ‘medical setting’ as a ‘controlled setting’, but the same idea of how it can affect a trip, applies. It seems Colorado might understand this a bit better, allowing for treatment outside of authorized service centers, but what this actually entails is not entirely clear.

Does being in a medical setting affect a psychedelic trip?

There isn’t one specific answer to this, and not everyone has the same requirements. For some people, the experience won’t differ greatly depending on set and setting, and for some people it will make all the difference. For everyone in between, well its hard to say. Plenty of trials for psychedelic medications have gone on at this point, and for those, we only get the results of the medical setting. Is it possible that results might have differed if the trials were run in a more familiar, or chosen, surrounding?

I came across an interesting statement when researching the Salvia divinorum plant, and the different ways that users describe the experience. Found in a Wired magazine article, and written by Daniel Oberhaus in 2020, the article details the writer’s own experience as a part of a research study into how the compound salvinorin A affects the brain during use. The trial took place at Johns Hopkins University in Baltimore, a research hospital, and involved being hooked up to an fMRI machine.

Per Oberhaus, “I had just inhaled an unspecified dose of the pure crystalline substance from a hose attached to what one of the researchers characterized as an ‘FDA-approved crack pipe.’” He continued, “My psychedelic experience in the fMRI machine was markedly less otherworldly. On the second round, I saw some colorful pinwheels and felt as though my body had merged with the machine. But I didn’t enter another dimension or dissolve into pure being”.

How much does set and setting affect psychedelic experience
How much does set and setting affect psychedelic experience

What are his thoughts as to why his experience in the trial differed from his experience using salvia illicitly, outside of a hospital setting? “This may have been because I received a lower dose. Or it may have been because it’s harder to give in to the experience when you’re inside a giant machine making a racket while it soaks your head in a powerful magnetic field.”

Being in an fMRI machine is much more extreme than simply sitting in a doctor’s office. But consider that most people who do ketamine illicitly, do it by snorting the drug; and one of the more common medical techniques is hooking someone up to an IV. The idea still resonates. Neither being stuck in a tube, or hooked up to an IV in a doctor’s office will likely be the chosen set and setting for many people. And no matter how comfortable you try to make a doctor’s office, it might still have the ability to change the experience.

Tack onto that the cost of the treatments, and this could make patients apprehensive about the outcome of their treatment, which could also affect experience. When getting a service is so expensive, you can’t mess around with it, and for people scraping to make this happen, there’s increased pressure to ‘get it right’. A less controlled environment could pose cost reduction ability, and make users more comfortable about what they’re spending.

My own experience in a medical setting for psychedelic treatment

On this particular topic, I can throw in my own opinion, as I did receive ketamine treatments in a doctor’s office, as well as having previously used the drug on my own illicitly. I’ll take a second to remind that ketamine is a dissociative hallucinogen, not a psychedelic. It is used for therapy in a similar way to psychedelics, and is currently the only legal way to get such treatment, as neither state thus far that legalized any form of a hallucinogen, started services yet.

I ended up in the office of a psychiatrist in Guadalajara, Mexico, which is one of the only places in Mexico that provides ketamine treatments. Most of the doctor’s business is for pain. I went because of sleep issues, which falls under psychiatric. There are very few people who do this there. As such, the procedure isn’t established like it is in American facilities; and from the beginning I was left to feel like not everything was being covered. I made the most of the experience, but looking back I can see how badly it went.

I was hooked up to an IV, and I sat in a comfortable enough place, but was it really? It was a kind of cold office, with no blanket offered, dim lighting, and no window. I was on a couch facing a desk, with very little around me. Sure, it was okay, but I wasn’t super comfortable. Nor did I like having an IV hooked up to me, or seeing the blood squirt out when they had a hard time getting my vein (both times!) I left with blood stains on my pants the second time. I didn’t enjoy the actual drug experience at all; it left me feeling queasy, shaky, and incredibly anxious. And while this could represent my own personal reaction to ketamine, there’s a problem here…

IV ketamine treatment in medical setting
IV ketamine treatment in medical setting

I did ketamine plenty illicitly. I used to do lines with an ex-boyfriend frequently enough to have a great idea how the drug affects me. I liked it back then. Not my favorite of all drug experiences, but very interesting. I used to feel like I was floating, disconnected, like my brain was pulling in different directions. But not bad. And at no point with the anxiety and discomfort I suffered in the doctor’s office. An anxiety so bad the doctor did not push me for another appointment (or even contact me again for follow-up…I would never got back to that provider).

The experiences were so wildly different, that it makes me wonder how much of my negative experience in the medical setting with the psychedelic-like drug, was related to being in that setting, rather than a place I am more comfortable with. My experience gives a huge amount of credence to the idea of at-home ketamine therapy, and the ability to do the treatment in the comfort and privacy of your chosen location. Perhaps under other circumstances, I would not have been a non-responder.

Conclusion

It’s not for me to say what works for other people. But when it comes to expensive treatments, or ‘services’, how many people want to pay out for something that isn’t what they’re looking for? And how much do we damage our own understanding of the usefulness of something, when the controls for use are so extreme? It’s not like these drugs are used illicitly in a medical setting; and people turn out just fine when using a psychedelic on their own, or in a less restrictive way. Maybe that’s something that should be remembered.

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2025

The Best Cocktails To Get You Through The Week

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The new year is starting with a bang – here are some cocktails to take off the edge.

The new year is coming in hot – back to work policies, the LA fires, snowstorms and just having to work is killing the 2025 start buzz.  Now drinking your problems away isn’t a good or healthy solution, but sometimes a nip of something does help. January is already known as a bit of depressing month due to the post-holiday blues, cold weather, shorter daylight hours, and the potential for increased financial stress after the holiday spree. Here are the best cocktails to get you through the week.

RELATED: Fitting Marijuana Into Your Winter Arc Routine

Paloma

What better way to start the year with a semi healthy drink. The Paloma with tequila and juice is somewhat healthy. Good tequila is low calorie, low body impact coupled with a big dose of vitamin C helps make the dark days a little brighter.

Ingredients

  • 2 ounces tequila
  • 1/2 ounce lime juice, freshly squeezed
  • 4 ounces Grapefruit soda, chilled, to top
  • Pinch of salt
  • Garnish: lime wheel

Create

  1. Add the tequila, lime juice, and pinch of salt to the glass, and fill with ice.
  2. Top with grapefruit soda, and stir briefly and gently to combine.
  3. Garnish with a lime wheel.

The Spaghett

While beer drinking is down as people switch to California sober, it is still highly popular. Why  now merge it with a favorite (Aperol Spritz and beer) for a refreshing and low alcohol treat?  Try it, you will like it.

Ingredients

  • 12 ounces light beer, such as Miller High Life
  • 1 ounce Campari

Create

  1. Take a big sip of chilled beer, about 1 ounce
  2. Pour campari into beer bottle
  3. Enjoy

Cucumber Cleanse

While friends talk about Dry January, Damp January, winter arc, and more – you can brag you are doing a cleanse. The lemon and cayenne juice cleanse is popular, you are just adding a lpersonal twist so it fits into happy hour or a tailgate. For the ginger syrup add 4 oz peeled while making simply syrup ginger and let it steep for 30 minutes.  Strain and use.

  • 2 ounces Absolut vodka
  • 3/4 ounce fresh cucumber juice
  • 1/2 ounce fresh lemon juice
  • 1/4 ounce ginger syrup
  • 1/4 ounce honey
  • 1 egg white
  • Dash of ground cayenne

Create

  1. Add all ingredients into a shaker and dry-shake (without ice) until frothy
  2. Add ice and shake again until well-chilled
  3. Strain into a cocktail glass
  4. Garnish with a sprinkle of ground cayenne

RELATED: Rainy Weather Cocktails

Dirty Shirley

Like the actress, the Shirley Temple cocktail was sweet, wholesome and popular.  But why not have the adult version of the beverage to start the year out breaking the norms?

Ingredients

  • 2 ozs gin
  • 1/2 oz orange juice
  • 1/2 oz lemon juice
  • 1 teaspoon grenadine
  • Orange slice

Create

  1. Combine all ingredients in a shake with ice
  2. Shake vigorously
  3. Strain into martini glass
  4. Garnish orange slice

 



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ABC Fine Wine &. Spritis

DoorDash Will Bring You THC

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DoorDash announced they will be delivering hemp THC and CBD!

In exciting news to every busy or lazy person out there, DoorDash will bring you THC. Yes, the popular food delivery platform, has expanded its offerings to include hemp-derived products in select markets, marking a significant shift in the on-demand delivery landscape. As of January 9, 2025, customers of legal age can now order a variety of hemp-derived THC and CBD products directly to their doorstep. Hemp is gaining in popularity and starting to pop up in liquor and convenience stores.

RELATED: Marijuana Users Gain Less Weight Than Non-Users

This new category includes items such as gummies, drinks, mints, chocolates, and honey sticks, all containing no more than 0.3% Delta-9 THC on a dry weight basis. The move comes in response to growing consumer demand for these products, with nearly 75% of adults aged 21-65 considering incorporating THC/ CBD products into their routine for relaxation and stress relief.

Photo by manish panghal via Unsplash

To access these products, eligible customers can simply select the CBD/THC tab in the DoorDash app, where they can browse and order from a selection of hemp-derived beverages, topicals, and edibles.

The company has implemented multiple safeguards, including electronic ID verification, to ensure that only customers of legal age can purchase these products. DoorDash is offering these products through various channels, including their own fulfillment platform, DashMart, as well as partnering with retailers like Total Wine & More and ABC Fine Wine & Spirits. This expansion allows DoorDash to tap into a growing market while providing consumers with convenient access to products they desire for relaxation and enjoyment.

This move by DoorDash reflects a broader trend in the delivery industry, as companies explore new product categories to meet evolving consumer preferences. However, it’s crucial to understand that these products have not been evaluated by the Food and Drug Administration for safety or efficacy.

As the market for hemp-derived products continues to grow, DoorDash’s entry into this space could potentially reshape the landscape of on-demand delivery services. It remains to be seen how this new offering will impact the company’s business and consumer behavior in the long term.

It’s important to note that while DoorDash is expanding into hemp-derived products, they are not delivering marijuana. The company is operating within the legal framework of the 2018 Farm Bill, which legalized hemp-derived products containing no more than 0.3% Delta-9 THC. Several key marijuana beverage and edible companies like Wana Brands have rolled out hemp products to expand their selection and to available in most states.



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Cannabis

Greenland And Cannabis

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People are chatting about the country right now, but what Greenland and cannabis? It is the world’s largest island and ruled by the Danish King. It is a self-governing territory of Denmark, but remains politically tied to the European country especially around currency, defense and foreign affairs. In Denmark, recreational use of cannabis is illegal, but medical use is permitted through a pilot program that began in 2018. The sale and use of cannabis is also tolerated in the Freetown Christiania neighborhood of Copenhagen.  The government revealed they could be open to expanding into a legal market in late 2023.

RELATED: Cannabis Can Help With Holiday Stomach Issues

Greenland is part of a European monarchy but is closer to North America.  Their nearest neighbors to the west of them, Canada and the United States both have some form of legal marijuana for over 50% of their population. But there is a tough history with Greenland and cannabis. Currently, cannabis is illegal on the island and less than 20% of the country consumes.  Excessive alcohol use is a big concern in the country.

icebergs on body of water under blue and white sky at daytime

Greenland has had an issue with marijuana use abuse with young people and recently announced a bold move towards a progressive drug policy. They are Greenland is exploring innovative approaches to address youth cannabis use, signaling a potential shift towards more comprehensive strategies. This Arctic nation, known for its breathtaking landscapes and rich cultural heritage, is now gaining attention for its forward-thinking approach.

Greenland’s government agency Allorfik has commissioned a groundbreaking project to explore effective service delivery models for combating youth cannabis use. This initiative demonstrates Greenland’s commitment to evidence-based solutions and public health-oriented approaches, rather than punitive measures that have proven ineffective in many parts of the world.

RELATED: The Most Popular Marijuana Flavors

Greenland’s efforts align with a growing global trend towards more nuanced and health-focused cannabis policies. As many countries and move towards legalization or decriminalization, there’s an increasing recognition of the need for thoughtful regulation and public health measures.



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