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UC Davis Launches Institute for Psychedelics and Neurotherapeutics

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University of California, Davis announced This week, “Advancing basic knowledge of the mechanisms of psychedelics and translating them into safe and effective treatments for diseases such as depression, post-traumatic stress disorder, addiction, Alzheimer’s disease and Parkinson’s disease. We are launching a new laboratory aimed at other people.

Called “The Institute for Psychedelics and Neurotherapeutics,” it “brings together scientists from different disciplines and partners with the pharmaceutical industry to ensure that important discoveries lead to new drugs for patients,” the university said in a statement. said the institute was “specially designed to foster collaboration across the campus.”

The institute will be “partially funded by donations of approximately $5 million from the Deans of the Arts and Sciences and the School of Medicine, the Vice Chancellor for Research, and the President’s Office,” the school said, adding that the funding will be in the same areas of study. Be distinguished from other centers involved.

“It’s also notable that the UC Davis Institute is supported by a large amount of the university’s funding, while other psychedelic science centers have formed around the country with donations from philanthropists,” the university said. says.

“Another unique feature of the UC Davis Institute is its focus on chemistry and the development of new neurotherapeutics,” the university said.

David E. Olson, associate professor in the Department of Chemistry and Department of Biochemistry and Molecular Medicine at the University of California, Davis, was appointed as the founder of the new laboratory.

“There are many therapeutic possibilities for psychedelics, but we can do better,” Olson said. The group published a paper three years ago. according to the university.

In Olson’s view, the university believes that “novel molecules tailored to specific disease indications will overcome many of the challenges traditional psychedelics currently face in terms of safety, scalability, and intellectual property.” By solving the problem, we could offer substantial benefits and open the door to industry partnerships.”

“Psychedelics have the unique ability to bring about long-lasting changes in the brain that are relevant to treatment of various conditions,” said Olson. “If we can take advantage of these beneficial properties while designing molecules that are safer and more scalable, we can help a lot of people.”

John A. Gray, Associate Professor in the Department of Neurology, will serve as Associate Director. Olson and Gray authored a study in 2018 that “demonstrates that psychedelics promote neural plasticity, the growth of new neurons and the formation of neural connections.”

“Neural atrophy is an important factor underlying many diseases, and the ability of hallucinogens to promote neuronal growth and new connections in the brain may have broad therapeutic implications.

The university said the institute “will draw on the extraordinary breadth of expertise of the UC Davis neuroscience community, which includes approximately 300 faculty members in centers, laboratories, and departments across the Davis and Sacramento campuses.” “is working on all aspects of psychedelic science, from molecules and cells to human clinical trials.”

“Combining the pioneering basic research team at the University of California, Davis, world-class neuroscientists, and the considerable expertise of a nationally recognized medical center is a breakthrough in helping patients locally and around the world. It’s a formula of success that we believe will lead to significant discoveries,” said Susan Mullin, dean of the School of Medicine, in a statement this week.



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Psychedelics

Lykos In Patent Mode On MDMA

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We don’t believe in taking out IP on MDMA

We don’t believe in taking out IP on MDMA

We don’t believe in taking out IP on MDMA

We don’t believe in taking out IP on MDMA

oh actually we do

 

 

Double Blind

In a shocking move that contradicts its previous stance on intellectual property, Lykos Therapeutics (formerly known as MAPS PBC) — the organization leading the movement to legalize MDMAassisted therapy — has filed multiple patent applications for specific forms and formulations of MDMA. Prior to this revelation, which was first reported on by Psychedelic Alpha, Lykos had long been praised in the psychedelic community and media for its “altruistic stance” in not seeking patent protections as part of its strategy, instead choosing to publish its research findings in scientific literature.

MAPS’s anti-patent stance, which intended to prevent MDMA from being monopolized, stood in stark contrast to the aggressive patent strategies of competitors like Compass Pathways and Atai Life Sciences. Rick Doblins, the founder of MAPS, had been analyzing the non-patentable status of MDMA since the late ‘80s, and in an article titled “MDMA Patentability and Orphan Drug Designation,” published in 1992, he wrote:

“It could be a major setback if MAPS funded MDMA research and secured approval for its medical use only to have someone else control it through an inexpensively obtained use patent.”

Read more

Lykos Therapeutics Quietly Moves to Patent MDMA

 



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Press Release: PsychedelicNewsWire Named Official Media Sponsor of the 4th Annual Psychedelic Therapeutics and Drug Development Conference

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LOS ANGELES, May 17, 2024 (GLOBE NEWSWIRE) — PsychedelicNewsWire (“PNW”), a specialized communications platform for the psychedelics sector and one of the 60+ brands powered by IBN (“InvestorBrandNetwork”), is pleased to announce that it will be the Official Media Sponsor for the 4th Annual Psychedelic Therapeutics and Drug Development Conference (“the conference”), an industry flagship event dedicated to research and development of psychedelics in the healthcare space hosted by Arrowhead SciTech Conferences & Events (“Arrowhead”). The event will be held at the iconic Revere Hotel Boston Common, 200 Stuart Street, Boston, MA 02116 on 23-24 May 2024



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individualized treatment

Risks of Psychedelics for People with Personality Disorders

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While psychedelics have shown promise in treating certain mental health conditions, a recent study suggests they may pose risks for individuals with personality disorders. The findings underscore the importance of careful screening and personalized approaches in psychedelic-assisted therapy.

Navigating the Psychedelic Landscape: Potential Risks for Individuals with Personality Disorders

Psychedelics, including substances like psilocybin and LSD, have gained significant traction in recent years for their potential therapeutic benefits in treating mental health conditions such as depression, anxiety, and PTSD. However, a recent publication in the Journal of Psychopharmacology has raised concerns about the suitability of these substances for individuals with personality disorders.

The study surveyed individuals who had used psychedelics and who were also diagnosed with personality disorders. A considerable number of respondents reported negative and persistent psychological impacts following their psychedelic experiences. Notably, these included heightened anxiety, paranoia, mood instability, and an exacerbation of existing personality disorder symptoms.

Researchers suggest that the vulnerability of individuals with personality disorders to the adverse effects of psychedelics may stem from pre-existing challenges in emotional regulation, self-identity, and interpersonal relationships. The profound and introspective nature of psychedelic experiences can intensify these issues, potentially leading to psychological distress and symptom aggravation.

This research highlights the critical need for thorough screening and assessment in the context of psychedelic-assisted therapy. It suggests that individuals with personality disorders might require tailored therapeutic approaches and robust support systems to navigate potential risks and to secure safe and positive outcomes.

Why It Matters

The burgeoning interest in psychedelic therapy underscores the necessity to discern both the potential benefits and risks across different demographic groups. This study contributes valuable insights, particularly for clinicians and researchers, stressing the importance of personalized treatment plans and the cautious consideration of individual vulnerabilities when administering psychedelic-assisted therapy.

Potential Implications

The findings from this study emphasize the need for ethical and responsible practices within the field of psychedelic-assisted therapy. There is a pressing requirement for the development of detailed screening protocols that can identify individuals who may be more susceptible to the adverse effects of psychedelics. Furthermore, crafting specialized therapeutic strategies that cater specifically to the needs of individuals with personality disorders is essential for ensuring their safety and overall well-being during and after undergoing psychedelic experiences.

The Bigger Picture

The debate surrounding the therapeutic use of psychedelics is complex, with various factors influencing the suitability of these treatments for different individuals. While there are promising results in general populations, the nuanced needs and potential vulnerabilities of those with personality disorders require careful consideration to prevent harm and maximize therapeutic outcomes. This necessitates ongoing research, improved clinical protocols, and a commitment to patient-centered care in the burgeoning field of psychedelic medicine.

Source: Science Alert



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